1YJWD

Crystal structure of quinupristin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords 23S RIBOSOMAL RNA
total genus 18
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2005-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 1yjwD00
1M90F 1VQ8D 1VQ6D 3CCRD 1VQKD 3CC2D 1K73F 5H1SH 1K9MF 3J7ZF 3G6ED 3CF5D 4IO9D 1W2BD 1M1KF 3CCJD 1VQ4D 2NRQA 1VQLD 1Q82F 1YI2D 2QEXD 1VQMD 3CD6D 3CC4D 3PIOD 2PZZA 5DM7D 3CCSD 1VQ7D 2QA4D 3CMAD 3OW2D 1KC8F 3C9GA 5HL7D 3DLLD 3CC7D 3CCMD 4WFAD 4IOCD 5JVHD 3CCQD 4UY8F 1YITD 1S72D 1VQ5D 1MJIA 1KQSD 1JJ2D 4IOAD 2ZJPD 4WFND 3CCLD 1VQPD 3CCUD 1VQOD 1YIJD 4U67D 4WFBD 3CMED 1N8RF 2NWUA 1K8AF 5GAEF 3CCED 1NJIF 3PIPD 3CXCD 2ZJQD 3CCVD 1Q86F 1YJND 2OTJD 3D7AA 3G4SD 4WF9D 3I55D 3CPWD 2WNYA 1IQ4A 2OGKA 2OTLD 1YJWD 3G71D 5MLCG 1YHQD 1KD1F 5DM6D 2ZJRD 1QVGD 1Q7YF 1Q81F 5GADF 4WCED 1VQ9D 1QVFD 5GAHF 5GAGF 3I56D 5JVGD 1VQND 1YJ9D
chains in the Genus database with same CATH superfamily
1M90F 1VQ8D 1VQ6D 3CCRD 1VQKD 3CC2D 1K73F 5H1SH 1K9MF 3J7ZF 3G6ED 3CF5D 4IO9D 1W2BD 1M1KF 3CCJD 1VQ4D 2NRQA 1VQLD 1Q82F 1YI2D 2QEXD 1VQMD 3CD6D 3CC4D 3PIOD 2PZZA 5DM7D 3CCSD 1VQ7D 2QA4D 3CMAD 3OW2D 1KC8F 3C9GA 5HL7D 3DLLD 3CC7D 3CCMD 4WFAD 4IOCD 5JVHD 3CCQD 4UY8F 1YITD 1S72D 1VQ5D 1MJIA 1KQSD 1JJ2D 4IOAD 2ZJPD 4WFND 3CCLD 1VQPD 3CCUD 1VQOD 1YIJD 4U67D 4WFBD 3CMED 1N8RF 2NWUA 1K8AF 5GAEF 3CCED 1NJIF 3PIPD 3CXCD 2ZJQD 3CCVD 1Q86F 1YJND 2OTJD 3D7AA 3G4SD 4WF9D 3I55D 3CPWD 2WNYA 1IQ4A 2OGKA 2OTLD 1YJWD 3G71D 5MLCG 1YHQD 1KD1F 5DM6D 2ZJRD 1QVGD 1Q7YF 1Q81F 5GADF 4WCED 1VQ9D 1QVFD 5GAHF 5GAGF 3I56D 5JVGD 1VQND 1YJ9D
chains in the Genus database with same CATH topology
1M90F 1VQ8D 1VQ6D 3CCRD 1VQKD 3CC2D 1K73F 5H1SH 1K9MF 3J7ZF 3G6ED 3CF5D 4IO9D 1W2BD 1M1KF 3CCJD 1VQ4D 2NRQA 1VQLD 1Q82F 1YI2D 2QEXD 1VQMD 3CD6D 3CC4D 3PIOD 2PZZA 5DM7D 3CCSD 1VQ7D 2QA4D 3CMAD 3OW2D 1KC8F 3C9GA 5HL7D 3DLLD 3CC7D 3CCMD 4WFAD 4IOCD 5JVHD 3CCQD 4UY8F 1YITD 1S72D 1VQ5D 1MJIA 1KQSD 1JJ2D 4IOAD 2ZJPD 4WFND 3CCLD 1VQPD 3CCUD 1VQOD 1YIJD 4U67D 4WFBD 3CMED 1N8RF 2NWUA 1K8AF 5GAEF 3CCED 1NJIF 3PIPD 3CXCD 2ZJQD 3CCVD 1Q86F 1YJND 2OTJD 3D7AA 3G4SD 4WF9D 3I55D 3CPWD 2WNYA 1IQ4A 2OGKA 2OTLD 1YJWD 3G71D 5MLCG 1YHQD 1KD1F 5DM6D 2ZJRD 1QVGD 1Q7YF 1Q81F 5GADF 4WCED 1VQ9D 1QVFD 5GAHF 5GAGF 3I56D 5JVGD 1VQND 1YJ9D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M90 F;  1VQ8 D;  1VQ6 D;  3CCR D;  1VQK D;  3CC2 D;  1K73 F;  5H1S H;  1K9M F;  3J7Z F;  3G6E D;  3CF5 D;  4IO9 D;  1W2B D;  1M1K F;  3CCJ D;  1VQ4 D;  2NRQ A;  1VQL D;  1Q82 F;  1YI2 D;  2QEX D;  1VQM D;  3CD6 D;  3CC4 D;  3PIO D;  2PZZ A;  5DM7 D;  3CCS D;  1VQ7 D;  2QA4 D;  3CMA D;  3OW2 D;  1KC8 F;  3C9G A;  5HL7 D;  3DLL D;  3CC7 D;  3CCM D;  4WFA D;  4IOC D;  5JVH D;  3CCQ D;  4UY8 F;  1YIT D;  1S72 D;  1VQ5 D;  1MJI A;  1KQS D;  1JJ2 D;  4IOA D;  2ZJP D;  4WFN D;  3CCL D;  1VQP D;  3CCU D;  1VQO D;  1YIJ D;  4U67 D;  4WFB D;  3CME D;  1N8R F;  2NWU A;  1K8A F;  5GAE F;  3CCE D;  1NJI F;  3PIP D;  3CXC D;  2ZJQ D;  3CCV D;  1Q86 F;  1YJN D;  2OTJ D;  3D7A A;  3G4S D;  4WF9 D;  3I55 D;  3CPW D;  2WNY A;  1IQ4 A;  2OGK A;  2OTL D;  1YJW D;  3G71 D;  5MLC G;  1YHQ D;  1KD1 F;  5DM6 D;  2ZJR D;  1QVG D;  1Q7Y F;  1Q81 F;  5GAD F;  4WCE D;  1VQ9 D;  1QVF D;  5GAH F;  5GAG F;  3I56 D;  5JVG D;  1VQN D;  1YJ9 D; 
#chains in the Genus database with same CATH topology
 1M90 F;  1VQ8 D;  1VQ6 D;  3CCR D;  1VQK D;  3CC2 D;  1K73 F;  5H1S H;  1K9M F;  3J7Z F;  3G6E D;  3CF5 D;  4IO9 D;  1W2B D;  1M1K F;  3CCJ D;  1VQ4 D;  2NRQ A;  1VQL D;  1Q82 F;  1YI2 D;  2QEX D;  1VQM D;  3CD6 D;  3CC4 D;  3PIO D;  2PZZ A;  5DM7 D;  3CCS D;  1VQ7 D;  2QA4 D;  3CMA D;  3OW2 D;  1KC8 F;  3C9G A;  5HL7 D;  3DLL D;  3CC7 D;  3CCM D;  4WFA D;  4IOC D;  5JVH D;  3CCQ D;  4UY8 F;  1YIT D;  1S72 D;  1VQ5 D;  1MJI A;  1KQS D;  1JJ2 D;  4IOA D;  2ZJP D;  4WFN D;  3CCL D;  1VQP D;  3CCU D;  1VQO D;  1YIJ D;  4U67 D;  4WFB D;  3CME D;  1N8R F;  2NWU A;  1K8A F;  5GAE F;  3CCE D;  1NJI F;  3PIP D;  3CXC D;  2ZJQ D;  3CCV D;  1Q86 F;  1YJN D;  2OTJ D;  3D7A A;  3G4S D;  4WF9 D;  3I55 D;  3CPW D;  2WNY A;  1IQ4 A;  2OGK A;  2OTL D;  1YJW D;  3G71 D;  5MLC G;  1YHQ D;  1KD1 F;  5DM6 D;  2ZJR D;  1QVG D;  1Q7Y F;  1Q81 F;  5GAD F;  4WCE D;  1VQ9 D;  1QVF D;  5GAH F;  5GAG F;  3I56 D;  5JVG D;  1VQN D;  1YJ9 D; 
#chains in the Genus database with same CATH homology
 1M90 F;  1VQ8 D;  1VQ6 D;  3CCR D;  1VQK D;  3CC2 D;  1K73 F;  5H1S H;  1K9M F;  3J7Z F;  3G6E D;  3CF5 D;  4IO9 D;  1W2B D;  1M1K F;  3CCJ D;  1VQ4 D;  2NRQ A;  1VQL D;  1Q82 F;  1YI2 D;  2QEX D;  1VQM D;  3CD6 D;  3CC4 D;  3PIO D;  2PZZ A;  5DM7 D;  3CCS D;  1VQ7 D;  2QA4 D;  3CMA D;  3OW2 D;  1KC8 F;  3C9G A;  5HL7 D;  3DLL D;  3CC7 D;  3CCM D;  4WFA D;  4IOC D;  5JVH D;  3CCQ D;  4UY8 F;  1YIT D;  1S72 D;  1VQ5 D;  1MJI A;  1KQS D;  1JJ2 D;  4IOA D;  2ZJP D;  4WFN D;  3CCL D;  1VQP D;  3CCU D;  1VQO D;  1YIJ D;  4U67 D;  4WFB D;  3CME D;  1N8R F;  2NWU A;  1K8A F;  5GAE F;  3CCE D;  1NJI F;  3PIP D;  3CXC D;  2ZJQ D;  3CCV D;  1Q86 F;  1YJN D;  2OTJ D;  3D7A A;  3G4S D;  4WF9 D;  3I55 D;  3CPW D;  2WNY A;  1IQ4 A;  2OGK A;  2OTL D;  1YJW D;  3G71 D;  5MLC G;  1YHQ D;  1KD1 F;  5DM6 D;  2ZJR D;  1QVG D;  1Q7Y F;  1Q81 F;  5GAD F;  4WCE D;  1VQ9 D;  1QVF D;  5GAH F;  5GAG F;  3I56 D;  5JVG D;  1VQN D;  1YJ9 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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