2NEFA

Hiv-1 nef (regulatory factor), nmr, 40 structures
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
136
structure length
136
Chain Sequence
AWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCYKLVPVEPEKLEEANKDDPEREVLEWRFDSRLAFHHMARELHPEYFKNA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Refined solution structure and backbone dynamics of HIV-1 Nef.
pubmed rcsb
molecule tags Regulatory factor
source organism Human immunodeficiency virus type 1
molecule keywords NEGATIVE FACTOR (F-PROTEIN)
total genus 18
structure length 136
sequence length 136
ec nomenclature
pdb deposition date 1997-02-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.62.10 Alpha Beta 2-Layer Sandwich Nef Regulatory Factor Nef Regulatory Factor 2nefA00
3RBBA 3REBA 4U5WA 3IOZA 1EFNB 2XI1B 4EMZB 2NEFA 4D8DB 3REAA 1AVZA 4EN2B 4NEEC 3IK5A 1AVVA 4ORZB 2XI1A
chains in the Genus database with same CATH superfamily
3RBBA 3REBA 4U5WA 3IOZA 1EFNB 2XI1B 4EMZB 2NEFA 4D8DB 3REAA 1AVZA 4EN2B 4NEEC 3IK5A 1AVVA 4ORZB 2XI1A
chains in the Genus database with same CATH topology
3RBBA 3REBA 4U5WA 3IOZA 1EFNB 2XI1B 4EMZB 2NEFA 4D8DB 3REAA 1AVZA 4EN2B 4NEEC 3IK5A 1AVVA 4ORZB 2XI1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RBB A;  3REB A;  4U5W A;  3IOZ A;  1EFN B;  2XI1 B;  4EMZ B;  2NEF A;  4D8D B;  3REA A;  1AVZ A;  4EN2 B;  4NEE C;  3IK5 A;  1AVV A;  4ORZ B;  2XI1 A; 
#chains in the Genus database with same CATH topology
 3RBB A;  3REB A;  4U5W A;  3IOZ A;  1EFN B;  2XI1 B;  4EMZ B;  2NEF A;  4D8D B;  3REA A;  1AVZ A;  4EN2 B;  4NEE C;  3IK5 A;  1AVV A;  4ORZ B;  2XI1 A; 
#chains in the Genus database with same CATH homology
 3RBB A;  3REB A;  4U5W A;  3IOZ A;  1EFN B;  2XI1 B;  4EMZ B;  2NEF A;  4D8D B;  3REA A;  1AVZ A;  4EN2 B;  4NEE C;  3IK5 A;  1AVV A;  4ORZ B;  2XI1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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