3CCJD

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 20
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3ccjD00
1M90F 2PZZA 1VQND 3I55D 3G4SD 3CC2D 1VQ9D 4IOCD 3CCUD 1KD1F 3CCJD 1VQOD 1YHQD 3CPWD 5GAEF 4WCED 3PIPD 1VQ8D 3OW2D 2QA4D 1KC8F 3CF5D 3G6ED 1Q81F 4WFND 2ZJRD 3CCSD 1K8AF 3CC4D 1VQLD 2OTLD 5HL7D 2NWUA 1YITD 2NRQA 1Q82F 1VQ6D 1MJIA 1VQKD 1JJ2D 3CCLD 1VQ4D 3DLLD 1YI2D 1QVFD 2WNYA 4IOAD 3CCMD 3I56D 5H1SH 2ZJPD 1N8RF 3CC7D 1VQPD 3J7ZF 1K73F 1S72D 5GAHF 2OGKA 5JVHD 5DM7D 3C9GA 1VQ7D 1NJIF 1VQMD 3CXCD 4IO9D 4UY8F 3CMED 4WFAD 1VQ5D 1KQSD 3CCVD 5GAGF 3D7AA 3CD6D 1M1KF 1IQ4A 3CMAD 2QEXD 5JVGD 1K9MF 5MLCG 1YJ9D 2OTJD 4WFBD 1Q86F 3CCQD 1YIJD 4WF9D 3G71D 1W2BD 5GADF 3PIOD 3CCRD 1YJND 1YJWD 4U67D 5DM6D 3CCED 1Q7YF 1QVGD 2ZJQD
chains in the Genus database with same CATH superfamily
1M90F 2PZZA 1VQND 3I55D 3G4SD 3CC2D 1VQ9D 4IOCD 3CCUD 1KD1F 3CCJD 1VQOD 1YHQD 3CPWD 5GAEF 4WCED 3PIPD 1VQ8D 3OW2D 2QA4D 1KC8F 3CF5D 3G6ED 1Q81F 4WFND 2ZJRD 3CCSD 1K8AF 3CC4D 1VQLD 2OTLD 5HL7D 2NWUA 1YITD 2NRQA 1Q82F 1VQ6D 1MJIA 1VQKD 1JJ2D 3CCLD 1VQ4D 3DLLD 1YI2D 1QVFD 2WNYA 4IOAD 3CCMD 3I56D 5H1SH 2ZJPD 1N8RF 3CC7D 1VQPD 3J7ZF 1K73F 1S72D 5GAHF 2OGKA 5JVHD 5DM7D 3C9GA 1VQ7D 1NJIF 1VQMD 3CXCD 4IO9D 4UY8F 3CMED 4WFAD 1VQ5D 1KQSD 3CCVD 5GAGF 3D7AA 3CD6D 1M1KF 1IQ4A 3CMAD 2QEXD 5JVGD 1K9MF 5MLCG 1YJ9D 2OTJD 4WFBD 1Q86F 3CCQD 1YIJD 4WF9D 3G71D 1W2BD 5GADF 3PIOD 3CCRD 1YJND 1YJWD 4U67D 5DM6D 3CCED 1Q7YF 1QVGD 2ZJQD
chains in the Genus database with same CATH topology
1M90F 2PZZA 1VQND 3I55D 3G4SD 3CC2D 1VQ9D 4IOCD 3CCUD 1KD1F 3CCJD 1VQOD 1YHQD 3CPWD 5GAEF 4WCED 3PIPD 1VQ8D 3OW2D 2QA4D 1KC8F 3CF5D 3G6ED 1Q81F 4WFND 2ZJRD 3CCSD 1K8AF 3CC4D 1VQLD 2OTLD 5HL7D 2NWUA 1YITD 2NRQA 1Q82F 1VQ6D 1MJIA 1VQKD 1JJ2D 3CCLD 1VQ4D 3DLLD 1YI2D 1QVFD 2WNYA 4IOAD 3CCMD 3I56D 5H1SH 2ZJPD 1N8RF 3CC7D 1VQPD 3J7ZF 1K73F 1S72D 5GAHF 2OGKA 5JVHD 5DM7D 3C9GA 1VQ7D 1NJIF 1VQMD 3CXCD 4IO9D 4UY8F 3CMED 4WFAD 1VQ5D 1KQSD 3CCVD 5GAGF 3D7AA 3CD6D 1M1KF 1IQ4A 3CMAD 2QEXD 5JVGD 1K9MF 5MLCG 1YJ9D 2OTJD 4WFBD 1Q86F 3CCQD 1YIJD 4WF9D 3G71D 1W2BD 5GADF 3PIOD 3CCRD 1YJND 1YJWD 4U67D 5DM6D 3CCED 1Q7YF 1QVGD 2ZJQD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M90 F;  2PZZ A;  1VQN D;  3I55 D;  3G4S D;  3CC2 D;  1VQ9 D;  4IOC D;  3CCU D;  1KD1 F;  3CCJ D;  1VQO D;  1YHQ D;  3CPW D;  5GAE F;  4WCE D;  3PIP D;  1VQ8 D;  3OW2 D;  2QA4 D;  1KC8 F;  3CF5 D;  3G6E D;  1Q81 F;  4WFN D;  2ZJR D;  3CCS D;  1K8A F;  3CC4 D;  1VQL D;  2OTL D;  5HL7 D;  2NWU A;  1YIT D;  2NRQ A;  1Q82 F;  1VQ6 D;  1MJI A;  1VQK D;  1JJ2 D;  3CCL D;  1VQ4 D;  3DLL D;  1YI2 D;  1QVF D;  2WNY A;  4IOA D;  3CCM D;  3I56 D;  5H1S H;  2ZJP D;  1N8R F;  3CC7 D;  1VQP D;  3J7Z F;  1K73 F;  1S72 D;  5GAH F;  2OGK A;  5JVH D;  5DM7 D;  3C9G A;  1VQ7 D;  1NJI F;  1VQM D;  3CXC D;  4IO9 D;  4UY8 F;  3CME D;  4WFA D;  1VQ5 D;  1KQS D;  3CCV D;  5GAG F;  3D7A A;  3CD6 D;  1M1K F;  1IQ4 A;  3CMA D;  2QEX D;  5JVG D;  1K9M F;  5MLC G;  1YJ9 D;  2OTJ D;  4WFB D;  1Q86 F;  3CCQ D;  1YIJ D;  4WF9 D;  3G71 D;  1W2B D;  5GAD F;  3PIO D;  3CCR D;  1YJN D;  1YJW D;  4U67 D;  5DM6 D;  3CCE D;  1Q7Y F;  1QVG D;  2ZJQ D; 
#chains in the Genus database with same CATH topology
 1M90 F;  2PZZ A;  1VQN D;  3I55 D;  3G4S D;  3CC2 D;  1VQ9 D;  4IOC D;  3CCU D;  1KD1 F;  3CCJ D;  1VQO D;  1YHQ D;  3CPW D;  5GAE F;  4WCE D;  3PIP D;  1VQ8 D;  3OW2 D;  2QA4 D;  1KC8 F;  3CF5 D;  3G6E D;  1Q81 F;  4WFN D;  2ZJR D;  3CCS D;  1K8A F;  3CC4 D;  1VQL D;  2OTL D;  5HL7 D;  2NWU A;  1YIT D;  2NRQ A;  1Q82 F;  1VQ6 D;  1MJI A;  1VQK D;  1JJ2 D;  3CCL D;  1VQ4 D;  3DLL D;  1YI2 D;  1QVF D;  2WNY A;  4IOA D;  3CCM D;  3I56 D;  5H1S H;  2ZJP D;  1N8R F;  3CC7 D;  1VQP D;  3J7Z F;  1K73 F;  1S72 D;  5GAH F;  2OGK A;  5JVH D;  5DM7 D;  3C9G A;  1VQ7 D;  1NJI F;  1VQM D;  3CXC D;  4IO9 D;  4UY8 F;  3CME D;  4WFA D;  1VQ5 D;  1KQS D;  3CCV D;  5GAG F;  3D7A A;  3CD6 D;  1M1K F;  1IQ4 A;  3CMA D;  2QEX D;  5JVG D;  1K9M F;  5MLC G;  1YJ9 D;  2OTJ D;  4WFB D;  1Q86 F;  3CCQ D;  1YIJ D;  4WF9 D;  3G71 D;  1W2B D;  5GAD F;  3PIO D;  3CCR D;  1YJN D;  1YJW D;  4U67 D;  5DM6 D;  3CCE D;  1Q7Y F;  1QVG D;  2ZJQ D; 
#chains in the Genus database with same CATH homology
 1M90 F;  2PZZ A;  1VQN D;  3I55 D;  3G4S D;  3CC2 D;  1VQ9 D;  4IOC D;  3CCU D;  1KD1 F;  3CCJ D;  1VQO D;  1YHQ D;  3CPW D;  5GAE F;  4WCE D;  3PIP D;  1VQ8 D;  3OW2 D;  2QA4 D;  1KC8 F;  3CF5 D;  3G6E D;  1Q81 F;  4WFN D;  2ZJR D;  3CCS D;  1K8A F;  3CC4 D;  1VQL D;  2OTL D;  5HL7 D;  2NWU A;  1YIT D;  2NRQ A;  1Q82 F;  1VQ6 D;  1MJI A;  1VQK D;  1JJ2 D;  3CCL D;  1VQ4 D;  3DLL D;  1YI2 D;  1QVF D;  2WNY A;  4IOA D;  3CCM D;  3I56 D;  5H1S H;  2ZJP D;  1N8R F;  3CC7 D;  1VQP D;  3J7Z F;  1K73 F;  1S72 D;  5GAH F;  2OGK A;  5JVH D;  5DM7 D;  3C9G A;  1VQ7 D;  1NJI F;  1VQM D;  3CXC D;  4IO9 D;  4UY8 F;  3CME D;  4WFA D;  1VQ5 D;  1KQS D;  3CCV D;  5GAG F;  3D7A A;  3CD6 D;  1M1K F;  1IQ4 A;  3CMA D;  2QEX D;  5JVG D;  1K9M F;  5MLC G;  1YJ9 D;  2OTJ D;  4WFB D;  1Q86 F;  3CCQ D;  1YIJ D;  4WF9 D;  3G71 D;  1W2B D;  5GAD F;  3PIO D;  3CCR D;  1YJN D;  1YJW D;  4U67 D;  5DM6 D;  3CCE D;  1Q7Y F;  1QVG D;  2ZJQ D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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