3CCVD

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 18
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3ccvD00
1IQ4A 1VQ5D 3CCLD 1NJIF 2QA4D 1VQND 2WNYA 3CCJD 1N8RF 3DLLD 3G6ED 3CCVD 1M1KF 2OGKA 2ZJRD 1Q7YF 5DM7D 5MLCG 1VQ8D 1W2BD 1VQ9D 1KC8F 3CCQD 4WF9D 1K9MF 3CCSD 3I56D 3CC7D 3CC2D 5JVHD 5HL7D 5JVGD 4UY8F 3CCED 3CMAD 1VQ4D 2NWUA 1YIJD 1Q86F 3D7AA 2OTLD 1QVFD 1VQ7D 1YHQD 2ZJQD 2OTJD 3OW2D 3G71D 5GAEF 5GAGF 2ZJPD 3G4SD 4WFND 3J7ZF 1MJIA 4IO9D 4IOCD 1M90F 4WFBD 3I55D 1YJWD 1VQKD 1Q81F 3CMED 5GADF 2NRQA 1YJND 1JJ2D 1YI2D 2PZZA 3CCUD 1KD1F 3C9GA 3CF5D 5GAHF 3CPWD 4U67D 1VQPD 1VQMD 3CD6D 2QEXD 3CCRD 1VQ6D 3CCMD 1QVGD 5DM6D 1Q82F 4IOAD 4WFAD 1KQSD 1S72D 4WCED 1K73F 3CXCD 1VQLD 3PIPD 3PIOD 5H1SH 1YJ9D 1YITD 3CC4D 1VQOD 1K8AF
chains in the Genus database with same CATH superfamily
1IQ4A 1VQ5D 3CCLD 1NJIF 2QA4D 1VQND 2WNYA 3CCJD 1N8RF 3DLLD 3G6ED 3CCVD 1M1KF 2OGKA 2ZJRD 1Q7YF 5DM7D 5MLCG 1VQ8D 1W2BD 1VQ9D 1KC8F 3CCQD 4WF9D 1K9MF 3CCSD 3I56D 3CC7D 3CC2D 5JVHD 5HL7D 5JVGD 4UY8F 3CCED 3CMAD 1VQ4D 2NWUA 1YIJD 1Q86F 3D7AA 2OTLD 1QVFD 1VQ7D 1YHQD 2ZJQD 2OTJD 3OW2D 3G71D 5GAEF 5GAGF 2ZJPD 3G4SD 4WFND 3J7ZF 1MJIA 4IO9D 4IOCD 1M90F 4WFBD 3I55D 1YJWD 1VQKD 1Q81F 3CMED 5GADF 2NRQA 1YJND 1JJ2D 1YI2D 2PZZA 3CCUD 1KD1F 3C9GA 3CF5D 5GAHF 3CPWD 4U67D 1VQPD 1VQMD 3CD6D 2QEXD 3CCRD 1VQ6D 3CCMD 1QVGD 5DM6D 1Q82F 4IOAD 4WFAD 1KQSD 1S72D 4WCED 1K73F 3CXCD 1VQLD 3PIPD 3PIOD 5H1SH 1YJ9D 1YITD 3CC4D 1VQOD 1K8AF
chains in the Genus database with same CATH topology
1IQ4A 1VQ5D 3CCLD 1NJIF 2QA4D 1VQND 2WNYA 3CCJD 1N8RF 3DLLD 3G6ED 3CCVD 1M1KF 2OGKA 2ZJRD 1Q7YF 5DM7D 5MLCG 1VQ8D 1W2BD 1VQ9D 1KC8F 3CCQD 4WF9D 1K9MF 3CCSD 3I56D 3CC7D 3CC2D 5JVHD 5HL7D 5JVGD 4UY8F 3CCED 3CMAD 1VQ4D 2NWUA 1YIJD 1Q86F 3D7AA 2OTLD 1QVFD 1VQ7D 1YHQD 2ZJQD 2OTJD 3OW2D 3G71D 5GAEF 5GAGF 2ZJPD 3G4SD 4WFND 3J7ZF 1MJIA 4IO9D 4IOCD 1M90F 4WFBD 3I55D 1YJWD 1VQKD 1Q81F 3CMED 5GADF 2NRQA 1YJND 1JJ2D 1YI2D 2PZZA 3CCUD 1KD1F 3C9GA 3CF5D 5GAHF 3CPWD 4U67D 1VQPD 1VQMD 3CD6D 2QEXD 3CCRD 1VQ6D 3CCMD 1QVGD 5DM6D 1Q82F 4IOAD 4WFAD 1KQSD 1S72D 4WCED 1K73F 3CXCD 1VQLD 3PIPD 3PIOD 5H1SH 1YJ9D 1YITD 3CC4D 1VQOD 1K8AF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IQ4 A;  1VQ5 D;  3CCL D;  1NJI F;  2QA4 D;  1VQN D;  2WNY A;  3CCJ D;  1N8R F;  3DLL D;  3G6E D;  3CCV D;  1M1K F;  2OGK A;  2ZJR D;  1Q7Y F;  5DM7 D;  5MLC G;  1VQ8 D;  1W2B D;  1VQ9 D;  1KC8 F;  3CCQ D;  4WF9 D;  1K9M F;  3CCS D;  3I56 D;  3CC7 D;  3CC2 D;  5JVH D;  5HL7 D;  5JVG D;  4UY8 F;  3CCE D;  3CMA D;  1VQ4 D;  2NWU A;  1YIJ D;  1Q86 F;  3D7A A;  2OTL D;  1QVF D;  1VQ7 D;  1YHQ D;  2ZJQ D;  2OTJ D;  3OW2 D;  3G71 D;  5GAE F;  5GAG F;  2ZJP D;  3G4S D;  4WFN D;  3J7Z F;  1MJI A;  4IO9 D;  4IOC D;  1M90 F;  4WFB D;  3I55 D;  1YJW D;  1VQK D;  1Q81 F;  3CME D;  5GAD F;  2NRQ A;  1YJN D;  1JJ2 D;  1YI2 D;  2PZZ A;  3CCU D;  1KD1 F;  3C9G A;  3CF5 D;  5GAH F;  3CPW D;  4U67 D;  1VQP D;  1VQM D;  3CD6 D;  2QEX D;  3CCR D;  1VQ6 D;  3CCM D;  1QVG D;  5DM6 D;  1Q82 F;  4IOA D;  4WFA D;  1KQS D;  1S72 D;  4WCE D;  1K73 F;  3CXC D;  1VQL D;  3PIP D;  3PIO D;  5H1S H;  1YJ9 D;  1YIT D;  3CC4 D;  1VQO D;  1K8A F; 
#chains in the Genus database with same CATH topology
 1IQ4 A;  1VQ5 D;  3CCL D;  1NJI F;  2QA4 D;  1VQN D;  2WNY A;  3CCJ D;  1N8R F;  3DLL D;  3G6E D;  3CCV D;  1M1K F;  2OGK A;  2ZJR D;  1Q7Y F;  5DM7 D;  5MLC G;  1VQ8 D;  1W2B D;  1VQ9 D;  1KC8 F;  3CCQ D;  4WF9 D;  1K9M F;  3CCS D;  3I56 D;  3CC7 D;  3CC2 D;  5JVH D;  5HL7 D;  5JVG D;  4UY8 F;  3CCE D;  3CMA D;  1VQ4 D;  2NWU A;  1YIJ D;  1Q86 F;  3D7A A;  2OTL D;  1QVF D;  1VQ7 D;  1YHQ D;  2ZJQ D;  2OTJ D;  3OW2 D;  3G71 D;  5GAE F;  5GAG F;  2ZJP D;  3G4S D;  4WFN D;  3J7Z F;  1MJI A;  4IO9 D;  4IOC D;  1M90 F;  4WFB D;  3I55 D;  1YJW D;  1VQK D;  1Q81 F;  3CME D;  5GAD F;  2NRQ A;  1YJN D;  1JJ2 D;  1YI2 D;  2PZZ A;  3CCU D;  1KD1 F;  3C9G A;  3CF5 D;  5GAH F;  3CPW D;  4U67 D;  1VQP D;  1VQM D;  3CD6 D;  2QEX D;  3CCR D;  1VQ6 D;  3CCM D;  1QVG D;  5DM6 D;  1Q82 F;  4IOA D;  4WFA D;  1KQS D;  1S72 D;  4WCE D;  1K73 F;  3CXC D;  1VQL D;  3PIP D;  3PIO D;  5H1S H;  1YJ9 D;  1YIT D;  3CC4 D;  1VQO D;  1K8A F; 
#chains in the Genus database with same CATH homology
 1IQ4 A;  1VQ5 D;  3CCL D;  1NJI F;  2QA4 D;  1VQN D;  2WNY A;  3CCJ D;  1N8R F;  3DLL D;  3G6E D;  3CCV D;  1M1K F;  2OGK A;  2ZJR D;  1Q7Y F;  5DM7 D;  5MLC G;  1VQ8 D;  1W2B D;  1VQ9 D;  1KC8 F;  3CCQ D;  4WF9 D;  1K9M F;  3CCS D;  3I56 D;  3CC7 D;  3CC2 D;  5JVH D;  5HL7 D;  5JVG D;  4UY8 F;  3CCE D;  3CMA D;  1VQ4 D;  2NWU A;  1YIJ D;  1Q86 F;  3D7A A;  2OTL D;  1QVF D;  1VQ7 D;  1YHQ D;  2ZJQ D;  2OTJ D;  3OW2 D;  3G71 D;  5GAE F;  5GAG F;  2ZJP D;  3G4S D;  4WFN D;  3J7Z F;  1MJI A;  4IO9 D;  4IOC D;  1M90 F;  4WFB D;  3I55 D;  1YJW D;  1VQK D;  1Q81 F;  3CME D;  5GAD F;  2NRQ A;  1YJN D;  1JJ2 D;  1YI2 D;  2PZZ A;  3CCU D;  1KD1 F;  3C9G A;  3CF5 D;  5GAH F;  3CPW D;  4U67 D;  1VQP D;  1VQM D;  3CD6 D;  2QEX D;  3CCR D;  1VQ6 D;  3CCM D;  1QVG D;  5DM6 D;  1Q82 F;  4IOA D;  4WFA D;  1KQS D;  1S72 D;  4WCE D;  1K73 F;  3CXC D;  1VQL D;  3PIP D;  3PIO D;  5H1S H;  1YJ9 D;  1YIT D;  3CC4 D;  1VQO D;  1K8A F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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