3CXCD

The structure of an enhanced oxazolidinone inhibitor bound to the 50s ribosomal subunit of h. marismortui
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S RIBOSOMAL RNA
total genus 21
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3cxcD00
1YIJD 1VQ6D 3C9GA 1QVGD 3I55D 1KQSD 3CCMD 5GADF 1VQ7D 3J7ZF 3CCVD 3G6ED 1YI2D 2ZJRD 1VQMD 5GAGF 4IOCD 4IO9D 1NJIF 4WCED 1S72D 3CCSD 5GAHF 1Q81F 3D7AA 1JJ2D 3CCQD 1Q7YF 3CPWD 4WFND 1N8RF 1YJWD 3PIOD 1VQKD 3CCUD 2NWUA 5JVGD 1QVFD 4IOAD 1K9MF 2ZJPD 3CD6D 1YITD 3PIPD 5H1SH 4WFAD 2QEXD 1VQ5D 2OTLD 4WF9D 1M1KF 5MLCG 4WFBD 5JVHD 5GAEF 5DM7D 3CCJD 1MJIA 1YJ9D 1KD1F 1VQ4D 3CXCD 3CCED 2ZJQD 2OTJD 3CC2D 3G4SD 2OGKA 1Q82F 1VQPD 1VQOD 3CCLD 1Q86F 2WNYA 3DLLD 3CCRD 1YJND 2PZZA 2QA4D 3CC7D 1VQND 1K73F 3CMED 1VQLD 4U67D 1M90F 3CF5D 1KC8F 3G71D 2NRQA 1K8AF 1YHQD 5HL7D 1VQ8D 1VQ9D 3CMAD 4UY8F 1IQ4A 3I56D 3OW2D 1W2BD 3CC4D 5DM6D
chains in the Genus database with same CATH superfamily
1YIJD 1VQ6D 3C9GA 1QVGD 3I55D 1KQSD 3CCMD 5GADF 1VQ7D 3J7ZF 3CCVD 3G6ED 1YI2D 2ZJRD 1VQMD 5GAGF 4IOCD 4IO9D 1NJIF 4WCED 1S72D 3CCSD 5GAHF 1Q81F 3D7AA 1JJ2D 3CCQD 1Q7YF 3CPWD 4WFND 1N8RF 1YJWD 3PIOD 1VQKD 3CCUD 2NWUA 5JVGD 1QVFD 4IOAD 1K9MF 2ZJPD 3CD6D 1YITD 3PIPD 5H1SH 4WFAD 2QEXD 1VQ5D 2OTLD 4WF9D 1M1KF 5MLCG 4WFBD 5JVHD 5GAEF 5DM7D 3CCJD 1MJIA 1YJ9D 1KD1F 1VQ4D 3CXCD 3CCED 2ZJQD 2OTJD 3CC2D 3G4SD 2OGKA 1Q82F 1VQPD 1VQOD 3CCLD 1Q86F 2WNYA 3DLLD 3CCRD 1YJND 2PZZA 2QA4D 3CC7D 1VQND 1K73F 3CMED 1VQLD 4U67D 1M90F 3CF5D 1KC8F 3G71D 2NRQA 1K8AF 1YHQD 5HL7D 1VQ8D 1VQ9D 3CMAD 4UY8F 1IQ4A 3I56D 3OW2D 1W2BD 3CC4D 5DM6D
chains in the Genus database with same CATH topology
1YIJD 1VQ6D 3C9GA 1QVGD 3I55D 1KQSD 3CCMD 5GADF 1VQ7D 3J7ZF 3CCVD 3G6ED 1YI2D 2ZJRD 1VQMD 5GAGF 4IOCD 4IO9D 1NJIF 4WCED 1S72D 3CCSD 5GAHF 1Q81F 3D7AA 1JJ2D 3CCQD 1Q7YF 3CPWD 4WFND 1N8RF 1YJWD 3PIOD 1VQKD 3CCUD 2NWUA 5JVGD 1QVFD 4IOAD 1K9MF 2ZJPD 3CD6D 1YITD 3PIPD 5H1SH 4WFAD 2QEXD 1VQ5D 2OTLD 4WF9D 1M1KF 5MLCG 4WFBD 5JVHD 5GAEF 5DM7D 3CCJD 1MJIA 1YJ9D 1KD1F 1VQ4D 3CXCD 3CCED 2ZJQD 2OTJD 3CC2D 3G4SD 2OGKA 1Q82F 1VQPD 1VQOD 3CCLD 1Q86F 2WNYA 3DLLD 3CCRD 1YJND 2PZZA 2QA4D 3CC7D 1VQND 1K73F 3CMED 1VQLD 4U67D 1M90F 3CF5D 1KC8F 3G71D 2NRQA 1K8AF 1YHQD 5HL7D 1VQ8D 1VQ9D 3CMAD 4UY8F 1IQ4A 3I56D 3OW2D 1W2BD 3CC4D 5DM6D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YIJ D;  1VQ6 D;  3C9G A;  1QVG D;  3I55 D;  1KQS D;  3CCM D;  5GAD F;  1VQ7 D;  3J7Z F;  3CCV D;  3G6E D;  1YI2 D;  2ZJR D;  1VQM D;  5GAG F;  4IOC D;  4IO9 D;  1NJI F;  4WCE D;  1S72 D;  3CCS D;  5GAH F;  1Q81 F;  3D7A A;  1JJ2 D;  3CCQ D;  1Q7Y F;  3CPW D;  4WFN D;  1N8R F;  1YJW D;  3PIO D;  1VQK D;  3CCU D;  2NWU A;  5JVG D;  1QVF D;  4IOA D;  1K9M F;  2ZJP D;  3CD6 D;  1YIT D;  3PIP D;  5H1S H;  4WFA D;  2QEX D;  1VQ5 D;  2OTL D;  4WF9 D;  1M1K F;  5MLC G;  4WFB D;  5JVH D;  5GAE F;  5DM7 D;  3CCJ D;  1MJI A;  1YJ9 D;  1KD1 F;  1VQ4 D;  3CXC D;  3CCE D;  2ZJQ D;  2OTJ D;  3CC2 D;  3G4S D;  2OGK A;  1Q82 F;  1VQP D;  1VQO D;  3CCL D;  1Q86 F;  2WNY A;  3DLL D;  3CCR D;  1YJN D;  2PZZ A;  2QA4 D;  3CC7 D;  1VQN D;  1K73 F;  3CME D;  1VQL D;  4U67 D;  1M90 F;  3CF5 D;  1KC8 F;  3G71 D;  2NRQ A;  1K8A F;  1YHQ D;  5HL7 D;  1VQ8 D;  1VQ9 D;  3CMA D;  4UY8 F;  1IQ4 A;  3I56 D;  3OW2 D;  1W2B D;  3CC4 D;  5DM6 D; 
#chains in the Genus database with same CATH topology
 1YIJ D;  1VQ6 D;  3C9G A;  1QVG D;  3I55 D;  1KQS D;  3CCM D;  5GAD F;  1VQ7 D;  3J7Z F;  3CCV D;  3G6E D;  1YI2 D;  2ZJR D;  1VQM D;  5GAG F;  4IOC D;  4IO9 D;  1NJI F;  4WCE D;  1S72 D;  3CCS D;  5GAH F;  1Q81 F;  3D7A A;  1JJ2 D;  3CCQ D;  1Q7Y F;  3CPW D;  4WFN D;  1N8R F;  1YJW D;  3PIO D;  1VQK D;  3CCU D;  2NWU A;  5JVG D;  1QVF D;  4IOA D;  1K9M F;  2ZJP D;  3CD6 D;  1YIT D;  3PIP D;  5H1S H;  4WFA D;  2QEX D;  1VQ5 D;  2OTL D;  4WF9 D;  1M1K F;  5MLC G;  4WFB D;  5JVH D;  5GAE F;  5DM7 D;  3CCJ D;  1MJI A;  1YJ9 D;  1KD1 F;  1VQ4 D;  3CXC D;  3CCE D;  2ZJQ D;  2OTJ D;  3CC2 D;  3G4S D;  2OGK A;  1Q82 F;  1VQP D;  1VQO D;  3CCL D;  1Q86 F;  2WNY A;  3DLL D;  3CCR D;  1YJN D;  2PZZ A;  2QA4 D;  3CC7 D;  1VQN D;  1K73 F;  3CME D;  1VQL D;  4U67 D;  1M90 F;  3CF5 D;  1KC8 F;  3G71 D;  2NRQ A;  1K8A F;  1YHQ D;  5HL7 D;  1VQ8 D;  1VQ9 D;  3CMA D;  4UY8 F;  1IQ4 A;  3I56 D;  3OW2 D;  1W2B D;  3CC4 D;  5DM6 D; 
#chains in the Genus database with same CATH homology
 1YIJ D;  1VQ6 D;  3C9G A;  1QVG D;  3I55 D;  1KQS D;  3CCM D;  5GAD F;  1VQ7 D;  3J7Z F;  3CCV D;  3G6E D;  1YI2 D;  2ZJR D;  1VQM D;  5GAG F;  4IOC D;  4IO9 D;  1NJI F;  4WCE D;  1S72 D;  3CCS D;  5GAH F;  1Q81 F;  3D7A A;  1JJ2 D;  3CCQ D;  1Q7Y F;  3CPW D;  4WFN D;  1N8R F;  1YJW D;  3PIO D;  1VQK D;  3CCU D;  2NWU A;  5JVG D;  1QVF D;  4IOA D;  1K9M F;  2ZJP D;  3CD6 D;  1YIT D;  3PIP D;  5H1S H;  4WFA D;  2QEX D;  1VQ5 D;  2OTL D;  4WF9 D;  1M1K F;  5MLC G;  4WFB D;  5JVH D;  5GAE F;  5DM7 D;  3CCJ D;  1MJI A;  1YJ9 D;  1KD1 F;  1VQ4 D;  3CXC D;  3CCE D;  2ZJQ D;  2OTJ D;  3CC2 D;  3G4S D;  2OGK A;  1Q82 F;  1VQP D;  1VQO D;  3CCL D;  1Q86 F;  2WNY A;  3DLL D;  3CCR D;  1YJN D;  2PZZ A;  2QA4 D;  3CC7 D;  1VQN D;  1K73 F;  3CME D;  1VQL D;  4U67 D;  1M90 F;  3CF5 D;  1KC8 F;  3G71 D;  2NRQ A;  1K8A F;  1YHQ D;  5HL7 D;  1VQ8 D;  1VQ9 D;  3CMA D;  4UY8 F;  1IQ4 A;  3I56 D;  3OW2 D;  1W2B D;  3CC4 D;  5DM6 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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