3PVIA

D34g mutant of pvuii endonuclease complexed with cognate dna shows that asp34 is directly involved in dna recognition and indirectly involved in catalysis
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
156
structure length
156
Chain Sequence
SHPDLNKLLELWPHIQEYQDLALKHGINDIFQGNGGKLLQVLLITGLTVLPGREGNDAVDNAGQEYELKSINIDLTKGFSTHHHMNPVIIAKYRQVPWIFAIYRGIAIEAIYRLEPKDLEFYYDKWERKWYSDGHKDINNPKIPVKYVMEHGTKIY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Asp34 of PvuII endonuclease is directly involved in DNA minor groove recognition and indirectly involved in catalysis.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Proteus vulgaris
molecule keywords DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3')
total genus 50
structure length 156
sequence length 156
chains with identical sequence B
ec nomenclature ec 3.1.21.4: Type II site-specific deoxyribonuclease.
pdb deposition date 1998-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09225 Endonuc-PvuII Restriction endonuclease PvuII
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.210.10 Alpha Beta 3-Layer(aba) Sandwich PvuII Endonuclease; Chain A PVUII Endonuclease, subunit A 3pviA00
1PVUA 1F0OA 1K0ZA 1PVIA 1H56A 1NI0A 1EYUA 2PVIA 3PVIA
chains in the Genus database with same CATH superfamily
2Q10A 2PVIA 1PVUA 4ESJA 4KYWA 1K0ZA 2ODHA 1F0OA 1PVIA 3IMBA 1H56A 1NI0A 1EYUA 2ODIA 3PVIA 2OA9A 2OAAA
chains in the Genus database with same CATH topology
1PVUA 1F0OA 1K0ZA 1PVIA 1H56A 1NI0A 1EYUA 2PVIA 3PVIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PVU A;  1F0O A;  1K0Z A;  1PVI A;  1H56 A;  1NI0 A;  1EYU A;  2PVI A;  3PVI A; 
#chains in the Genus database with same CATH topology
 2Q10 A;  2PVI A;  1PVU A;  4ESJ A;  4KYW A;  1K0Z A;  2ODH A;  1F0O A;  1PVI A;  3IMB A;  1H56 A;  1NI0 A;  1EYU A;  2ODI A;  3PVI A;  2OA9 A;  2OAA A; 
#chains in the Genus database with same CATH homology
 1PVU A;  1F0O A;  1K0Z A;  1PVI A;  1H56 A;  1NI0 A;  1EYU A;  2PVI A;  3PVI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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