3CC4D

Co-crystal structure of anisomycin bound to the 50s ribosomal subunit
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 16
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3cc4D00
5JVHD 1K73F 3CD6D 3DLLD 5H1SH 3CCMD 3CC7D 5HL7D 2ZJPD 4U67D 3G6ED 2PZZA 2ZJRD 1MJIA 2OTJD 2QA4D 1VQLD 3CCED 4WCED 3CC2D 1N8RF 3I55D 1VQMD 1VQ7D 5MLCG 3D7AA 3CF5D 3PIOD 1Q82F 1Q86F 1QVFD 1VQOD 3CCJD 1YITD 1NJIF 1IQ4A 4IOAD 1KQSD 3CCVD 1S72D 1K8AF 1M1KF 1VQKD 3CCUD 4WF9D 3CMAD 1JJ2D 1VQ5D 2WNYA 3CMED 3C9GA 4IOCD 4WFND 1VQ8D 3CCLD 1KC8F 1VQ6D 4UY8F 3G4SD 3CC4D 5GAGF 3CCQD 3PIPD 1K9MF 2NRQA 4IO9D 2NWUA 4WFAD 5GAHF 1YIJD 1KD1F 1W2BD 1YHQD 1Q81F 1VQ4D 1Q7YF 3CXCD 4WFBD 5DM6D 3CPWD 1QVGD 1YJND 1M90F 2QEXD 1YJ9D 3I56D 1VQND 3CCSD 2OGKA 1YI2D 5GAEF 3CCRD 1VQ9D 2OTLD 3G71D 3J7ZF 1YJWD 2ZJQD 1VQPD 5JVGD 5GADF 3OW2D 5DM7D
chains in the Genus database with same CATH superfamily
5JVHD 1K73F 3CD6D 3DLLD 5H1SH 3CCMD 3CC7D 5HL7D 2ZJPD 4U67D 3G6ED 2PZZA 2ZJRD 1MJIA 2OTJD 2QA4D 1VQLD 3CCED 4WCED 3CC2D 1N8RF 3I55D 1VQMD 1VQ7D 5MLCG 3D7AA 3CF5D 3PIOD 1Q82F 1Q86F 1QVFD 1VQOD 3CCJD 1YITD 1NJIF 1IQ4A 4IOAD 1KQSD 3CCVD 1S72D 1K8AF 1M1KF 1VQKD 3CCUD 4WF9D 3CMAD 1JJ2D 1VQ5D 2WNYA 3CMED 3C9GA 4IOCD 4WFND 1VQ8D 3CCLD 1KC8F 1VQ6D 4UY8F 3G4SD 3CC4D 5GAGF 3CCQD 3PIPD 1K9MF 2NRQA 4IO9D 2NWUA 4WFAD 5GAHF 1YIJD 1KD1F 1W2BD 1YHQD 1Q81F 1VQ4D 1Q7YF 3CXCD 4WFBD 5DM6D 3CPWD 1QVGD 1YJND 1M90F 2QEXD 1YJ9D 3I56D 1VQND 3CCSD 2OGKA 1YI2D 5GAEF 3CCRD 1VQ9D 2OTLD 3G71D 3J7ZF 1YJWD 2ZJQD 1VQPD 5JVGD 5GADF 3OW2D 5DM7D
chains in the Genus database with same CATH topology
5JVHD 1K73F 3CD6D 3DLLD 5H1SH 3CCMD 3CC7D 5HL7D 2ZJPD 4U67D 3G6ED 2PZZA 2ZJRD 1MJIA 2OTJD 2QA4D 1VQLD 3CCED 4WCED 3CC2D 1N8RF 3I55D 1VQMD 1VQ7D 5MLCG 3D7AA 3CF5D 3PIOD 1Q82F 1Q86F 1QVFD 1VQOD 3CCJD 1YITD 1NJIF 1IQ4A 4IOAD 1KQSD 3CCVD 1S72D 1K8AF 1M1KF 1VQKD 3CCUD 4WF9D 3CMAD 1JJ2D 1VQ5D 2WNYA 3CMED 3C9GA 4IOCD 4WFND 1VQ8D 3CCLD 1KC8F 1VQ6D 4UY8F 3G4SD 3CC4D 5GAGF 3CCQD 3PIPD 1K9MF 2NRQA 4IO9D 2NWUA 4WFAD 5GAHF 1YIJD 1KD1F 1W2BD 1YHQD 1Q81F 1VQ4D 1Q7YF 3CXCD 4WFBD 5DM6D 3CPWD 1QVGD 1YJND 1M90F 2QEXD 1YJ9D 3I56D 1VQND 3CCSD 2OGKA 1YI2D 5GAEF 3CCRD 1VQ9D 2OTLD 3G71D 3J7ZF 1YJWD 2ZJQD 1VQPD 5JVGD 5GADF 3OW2D 5DM7D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JVH D;  1K73 F;  3CD6 D;  3DLL D;  5H1S H;  3CCM D;  3CC7 D;  5HL7 D;  2ZJP D;  4U67 D;  3G6E D;  2PZZ A;  2ZJR D;  1MJI A;  2OTJ D;  2QA4 D;  1VQL D;  3CCE D;  4WCE D;  3CC2 D;  1N8R F;  3I55 D;  1VQM D;  1VQ7 D;  5MLC G;  3D7A A;  3CF5 D;  3PIO D;  1Q82 F;  1Q86 F;  1QVF D;  1VQO D;  3CCJ D;  1YIT D;  1NJI F;  1IQ4 A;  4IOA D;  1KQS D;  3CCV D;  1S72 D;  1K8A F;  1M1K F;  1VQK D;  3CCU D;  4WF9 D;  3CMA D;  1JJ2 D;  1VQ5 D;  2WNY A;  3CME D;  3C9G A;  4IOC D;  4WFN D;  1VQ8 D;  3CCL D;  1KC8 F;  1VQ6 D;  4UY8 F;  3G4S D;  3CC4 D;  5GAG F;  3CCQ D;  3PIP D;  1K9M F;  2NRQ A;  4IO9 D;  2NWU A;  4WFA D;  5GAH F;  1YIJ D;  1KD1 F;  1W2B D;  1YHQ D;  1Q81 F;  1VQ4 D;  1Q7Y F;  3CXC D;  4WFB D;  5DM6 D;  3CPW D;  1QVG D;  1YJN D;  1M90 F;  2QEX D;  1YJ9 D;  3I56 D;  1VQN D;  3CCS D;  2OGK A;  1YI2 D;  5GAE F;  3CCR D;  1VQ9 D;  2OTL D;  3G71 D;  3J7Z F;  1YJW D;  2ZJQ D;  1VQP D;  5JVG D;  5GAD F;  3OW2 D;  5DM7 D; 
#chains in the Genus database with same CATH topology
 5JVH D;  1K73 F;  3CD6 D;  3DLL D;  5H1S H;  3CCM D;  3CC7 D;  5HL7 D;  2ZJP D;  4U67 D;  3G6E D;  2PZZ A;  2ZJR D;  1MJI A;  2OTJ D;  2QA4 D;  1VQL D;  3CCE D;  4WCE D;  3CC2 D;  1N8R F;  3I55 D;  1VQM D;  1VQ7 D;  5MLC G;  3D7A A;  3CF5 D;  3PIO D;  1Q82 F;  1Q86 F;  1QVF D;  1VQO D;  3CCJ D;  1YIT D;  1NJI F;  1IQ4 A;  4IOA D;  1KQS D;  3CCV D;  1S72 D;  1K8A F;  1M1K F;  1VQK D;  3CCU D;  4WF9 D;  3CMA D;  1JJ2 D;  1VQ5 D;  2WNY A;  3CME D;  3C9G A;  4IOC D;  4WFN D;  1VQ8 D;  3CCL D;  1KC8 F;  1VQ6 D;  4UY8 F;  3G4S D;  3CC4 D;  5GAG F;  3CCQ D;  3PIP D;  1K9M F;  2NRQ A;  4IO9 D;  2NWU A;  4WFA D;  5GAH F;  1YIJ D;  1KD1 F;  1W2B D;  1YHQ D;  1Q81 F;  1VQ4 D;  1Q7Y F;  3CXC D;  4WFB D;  5DM6 D;  3CPW D;  1QVG D;  1YJN D;  1M90 F;  2QEX D;  1YJ9 D;  3I56 D;  1VQN D;  3CCS D;  2OGK A;  1YI2 D;  5GAE F;  3CCR D;  1VQ9 D;  2OTL D;  3G71 D;  3J7Z F;  1YJW D;  2ZJQ D;  1VQP D;  5JVG D;  5GAD F;  3OW2 D;  5DM7 D; 
#chains in the Genus database with same CATH homology
 5JVH D;  1K73 F;  3CD6 D;  3DLL D;  5H1S H;  3CCM D;  3CC7 D;  5HL7 D;  2ZJP D;  4U67 D;  3G6E D;  2PZZ A;  2ZJR D;  1MJI A;  2OTJ D;  2QA4 D;  1VQL D;  3CCE D;  4WCE D;  3CC2 D;  1N8R F;  3I55 D;  1VQM D;  1VQ7 D;  5MLC G;  3D7A A;  3CF5 D;  3PIO D;  1Q82 F;  1Q86 F;  1QVF D;  1VQO D;  3CCJ D;  1YIT D;  1NJI F;  1IQ4 A;  4IOA D;  1KQS D;  3CCV D;  1S72 D;  1K8A F;  1M1K F;  1VQK D;  3CCU D;  4WF9 D;  3CMA D;  1JJ2 D;  1VQ5 D;  2WNY A;  3CME D;  3C9G A;  4IOC D;  4WFN D;  1VQ8 D;  3CCL D;  1KC8 F;  1VQ6 D;  4UY8 F;  3G4S D;  3CC4 D;  5GAG F;  3CCQ D;  3PIP D;  1K9M F;  2NRQ A;  4IO9 D;  2NWU A;  4WFA D;  5GAH F;  1YIJ D;  1KD1 F;  1W2B D;  1YHQ D;  1Q81 F;  1VQ4 D;  1Q7Y F;  3CXC D;  4WFB D;  5DM6 D;  3CPW D;  1QVG D;  1YJN D;  1M90 F;  2QEX D;  1YJ9 D;  3I56 D;  1VQN D;  3CCS D;  2OGK A;  1YI2 D;  5GAE F;  3CCR D;  1VQ9 D;  2OTL D;  3G71 D;  3J7Z F;  1YJW D;  2ZJQ D;  1VQP D;  5JVG D;  5GAD F;  3OW2 D;  5DM7 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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