3CC7D

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2487u
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 18
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3cc7D00
5JVGD 4IOCD 3G4SD 3CCMD 5GADF 1YHQD 5GAEF 3CF5D 1QVGD 1Q81F 4U67D 1NJIF 1YJND 1N8RF 4IOAD 4WFBD 3CC2D 1YIJD 1K8AF 2ZJPD 3CCLD 1VQ9D 1VQLD 4WFAD 3CCVD 1YJ9D 1MJIA 1S72D 2OTLD 5HL7D 2ZJRD 4IO9D 3CCQD 2ZJQD 4WCED 2OTJD 3CCRD 1KC8F 3D7AA 3G71D 3PIOD 1K73F 1YJWD 5MLCG 2QA4D 3CMAD 5H1SH 1VQ7D 3C9GA 3CCED 1VQ8D 2NWUA 4WFND 3CCUD 3CD6D 5DM6D 3J7ZF 1IQ4A 5DM7D 3DLLD 3CC7D 5GAHF 3PIPD 1QVFD 1Q86F 3G6ED 3CC4D 3I56D 1W2BD 1VQND 3CCJD 3CMED 5JVHD 1VQMD 1VQ4D 4UY8F 1VQPD 3CPWD 1VQOD 1M90F 1VQ5D 5GAGF 3CXCD 1K9MF 1M1KF 1YITD 1YI2D 2NRQA 1Q82F 1KQSD 3CCSD 1VQ6D 2OGKA 1KD1F 3OW2D 2PZZA 3I55D 2WNYA 4WF9D 1VQKD 1Q7YF 1JJ2D 2QEXD
chains in the Genus database with same CATH superfamily
5JVGD 4IOCD 3G4SD 3CCMD 5GADF 1YHQD 5GAEF 3CF5D 1QVGD 1Q81F 4U67D 1NJIF 1YJND 1N8RF 4IOAD 4WFBD 3CC2D 1YIJD 1K8AF 2ZJPD 3CCLD 1VQ9D 1VQLD 4WFAD 3CCVD 1YJ9D 1MJIA 1S72D 2OTLD 5HL7D 2ZJRD 4IO9D 3CCQD 2ZJQD 4WCED 2OTJD 3CCRD 1KC8F 3D7AA 3G71D 3PIOD 1K73F 1YJWD 5MLCG 2QA4D 3CMAD 5H1SH 1VQ7D 3C9GA 3CCED 1VQ8D 2NWUA 4WFND 3CCUD 3CD6D 5DM6D 3J7ZF 1IQ4A 5DM7D 3DLLD 3CC7D 5GAHF 3PIPD 1QVFD 1Q86F 3G6ED 3CC4D 3I56D 1W2BD 1VQND 3CCJD 3CMED 5JVHD 1VQMD 1VQ4D 4UY8F 1VQPD 3CPWD 1VQOD 1M90F 1VQ5D 5GAGF 3CXCD 1K9MF 1M1KF 1YITD 1YI2D 2NRQA 1Q82F 1KQSD 3CCSD 1VQ6D 2OGKA 1KD1F 3OW2D 2PZZA 3I55D 2WNYA 4WF9D 1VQKD 1Q7YF 1JJ2D 2QEXD
chains in the Genus database with same CATH topology
5JVGD 4IOCD 3G4SD 3CCMD 5GADF 1YHQD 5GAEF 3CF5D 1QVGD 1Q81F 4U67D 1NJIF 1YJND 1N8RF 4IOAD 4WFBD 3CC2D 1YIJD 1K8AF 2ZJPD 3CCLD 1VQ9D 1VQLD 4WFAD 3CCVD 1YJ9D 1MJIA 1S72D 2OTLD 5HL7D 2ZJRD 4IO9D 3CCQD 2ZJQD 4WCED 2OTJD 3CCRD 1KC8F 3D7AA 3G71D 3PIOD 1K73F 1YJWD 5MLCG 2QA4D 3CMAD 5H1SH 1VQ7D 3C9GA 3CCED 1VQ8D 2NWUA 4WFND 3CCUD 3CD6D 5DM6D 3J7ZF 1IQ4A 5DM7D 3DLLD 3CC7D 5GAHF 3PIPD 1QVFD 1Q86F 3G6ED 3CC4D 3I56D 1W2BD 1VQND 3CCJD 3CMED 5JVHD 1VQMD 1VQ4D 4UY8F 1VQPD 3CPWD 1VQOD 1M90F 1VQ5D 5GAGF 3CXCD 1K9MF 1M1KF 1YITD 1YI2D 2NRQA 1Q82F 1KQSD 3CCSD 1VQ6D 2OGKA 1KD1F 3OW2D 2PZZA 3I55D 2WNYA 4WF9D 1VQKD 1Q7YF 1JJ2D 2QEXD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JVG D;  4IOC D;  3G4S D;  3CCM D;  5GAD F;  1YHQ D;  5GAE F;  3CF5 D;  1QVG D;  1Q81 F;  4U67 D;  1NJI F;  1YJN D;  1N8R F;  4IOA D;  4WFB D;  3CC2 D;  1YIJ D;  1K8A F;  2ZJP D;  3CCL D;  1VQ9 D;  1VQL D;  4WFA D;  3CCV D;  1YJ9 D;  1MJI A;  1S72 D;  2OTL D;  5HL7 D;  2ZJR D;  4IO9 D;  3CCQ D;  2ZJQ D;  4WCE D;  2OTJ D;  3CCR D;  1KC8 F;  3D7A A;  3G71 D;  3PIO D;  1K73 F;  1YJW D;  5MLC G;  2QA4 D;  3CMA D;  5H1S H;  1VQ7 D;  3C9G A;  3CCE D;  1VQ8 D;  2NWU A;  4WFN D;  3CCU D;  3CD6 D;  5DM6 D;  3J7Z F;  1IQ4 A;  5DM7 D;  3DLL D;  3CC7 D;  5GAH F;  3PIP D;  1QVF D;  1Q86 F;  3G6E D;  3CC4 D;  3I56 D;  1W2B D;  1VQN D;  3CCJ D;  3CME D;  5JVH D;  1VQM D;  1VQ4 D;  4UY8 F;  1VQP D;  3CPW D;  1VQO D;  1M90 F;  1VQ5 D;  5GAG F;  3CXC D;  1K9M F;  1M1K F;  1YIT D;  1YI2 D;  2NRQ A;  1Q82 F;  1KQS D;  3CCS D;  1VQ6 D;  2OGK A;  1KD1 F;  3OW2 D;  2PZZ A;  3I55 D;  2WNY A;  4WF9 D;  1VQK D;  1Q7Y F;  1JJ2 D;  2QEX D; 
#chains in the Genus database with same CATH topology
 5JVG D;  4IOC D;  3G4S D;  3CCM D;  5GAD F;  1YHQ D;  5GAE F;  3CF5 D;  1QVG D;  1Q81 F;  4U67 D;  1NJI F;  1YJN D;  1N8R F;  4IOA D;  4WFB D;  3CC2 D;  1YIJ D;  1K8A F;  2ZJP D;  3CCL D;  1VQ9 D;  1VQL D;  4WFA D;  3CCV D;  1YJ9 D;  1MJI A;  1S72 D;  2OTL D;  5HL7 D;  2ZJR D;  4IO9 D;  3CCQ D;  2ZJQ D;  4WCE D;  2OTJ D;  3CCR D;  1KC8 F;  3D7A A;  3G71 D;  3PIO D;  1K73 F;  1YJW D;  5MLC G;  2QA4 D;  3CMA D;  5H1S H;  1VQ7 D;  3C9G A;  3CCE D;  1VQ8 D;  2NWU A;  4WFN D;  3CCU D;  3CD6 D;  5DM6 D;  3J7Z F;  1IQ4 A;  5DM7 D;  3DLL D;  3CC7 D;  5GAH F;  3PIP D;  1QVF D;  1Q86 F;  3G6E D;  3CC4 D;  3I56 D;  1W2B D;  1VQN D;  3CCJ D;  3CME D;  5JVH D;  1VQM D;  1VQ4 D;  4UY8 F;  1VQP D;  3CPW D;  1VQO D;  1M90 F;  1VQ5 D;  5GAG F;  3CXC D;  1K9M F;  1M1K F;  1YIT D;  1YI2 D;  2NRQ A;  1Q82 F;  1KQS D;  3CCS D;  1VQ6 D;  2OGK A;  1KD1 F;  3OW2 D;  2PZZ A;  3I55 D;  2WNY A;  4WF9 D;  1VQK D;  1Q7Y F;  1JJ2 D;  2QEX D; 
#chains in the Genus database with same CATH homology
 5JVG D;  4IOC D;  3G4S D;  3CCM D;  5GAD F;  1YHQ D;  5GAE F;  3CF5 D;  1QVG D;  1Q81 F;  4U67 D;  1NJI F;  1YJN D;  1N8R F;  4IOA D;  4WFB D;  3CC2 D;  1YIJ D;  1K8A F;  2ZJP D;  3CCL D;  1VQ9 D;  1VQL D;  4WFA D;  3CCV D;  1YJ9 D;  1MJI A;  1S72 D;  2OTL D;  5HL7 D;  2ZJR D;  4IO9 D;  3CCQ D;  2ZJQ D;  4WCE D;  2OTJ D;  3CCR D;  1KC8 F;  3D7A A;  3G71 D;  3PIO D;  1K73 F;  1YJW D;  5MLC G;  2QA4 D;  3CMA D;  5H1S H;  1VQ7 D;  3C9G A;  3CCE D;  1VQ8 D;  2NWU A;  4WFN D;  3CCU D;  3CD6 D;  5DM6 D;  3J7Z F;  1IQ4 A;  5DM7 D;  3DLL D;  3CC7 D;  5GAH F;  3PIP D;  1QVF D;  1Q86 F;  3G6E D;  3CC4 D;  3I56 D;  1W2B D;  1VQN D;  3CCJ D;  3CME D;  5JVH D;  1VQM D;  1VQ4 D;  4UY8 F;  1VQP D;  3CPW D;  1VQO D;  1M90 F;  1VQ5 D;  5GAG F;  3CXC D;  1K9M F;  1M1K F;  1YIT D;  1YI2 D;  2NRQ A;  1Q82 F;  1KQS D;  3CCS D;  1VQ6 D;  2OGK A;  1KD1 F;  3OW2 D;  2PZZ A;  3I55 D;  2WNY A;  4WF9 D;  1VQK D;  1Q7Y F;  1JJ2 D;  2QEX D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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