3CCJD

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation c2534u
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 20
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3ccjD00
1Q86F 1VQLD 4WFBD 3CCED 1YJND 3C9GA 3CC7D 3PIPD 1KD1F 2OTJD 1VQKD 1VQOD 3D7AA 3G71D 2ZJPD 1IQ4A 3CCVD 4WFND 5DM7D 2PZZA 1YJWD 1YJ9D 1N8RF 1NJIF 3CC2D 3I56D 2QA4D 4IOCD 3CCSD 1Q82F 3CPWD 3I55D 3CMED 3J7ZF 3CD6D 3CCJD 3CCMD 4WCED 5MLCG 2WNYA 1YHQD 4IOAD 2NWUA 1YI2D 1K73F 4WF9D 1Q81F 3CCQD 1VQMD 5GAGF 1KC8F 1S72D 3CMAD 1VQ5D 1JJ2D 2QEXD 1VQ7D 1K8AF 2OGKA 1VQ9D 3CCUD 1M90F 5H1SH 5GADF 3CF5D 3CC4D 3G4SD 3G6ED 5GAHF 4U67D 4UY8F 1K9MF 1VQ8D 3CCLD 5HL7D 1W2BD 3PIOD 1M1KF 3OW2D 3CCRD 1KQSD 1YIJD 1VQND 1VQPD 1MJIA 1YITD 1VQ4D 5DM6D 5JVHD 3DLLD 4WFAD 2ZJQD 2OTLD 4IO9D 5JVGD 1VQ6D 5GAEF 3CXCD 1Q7YF 1QVGD 2ZJRD 1QVFD 2NRQA
chains in the Genus database with same CATH superfamily
1Q86F 1VQLD 4WFBD 3CCED 1YJND 3C9GA 3CC7D 3PIPD 1KD1F 2OTJD 1VQKD 1VQOD 3D7AA 3G71D 2ZJPD 1IQ4A 3CCVD 4WFND 5DM7D 2PZZA 1YJWD 1YJ9D 1N8RF 1NJIF 3CC2D 3I56D 2QA4D 4IOCD 3CCSD 1Q82F 3CPWD 3I55D 3CMED 3J7ZF 3CD6D 3CCJD 3CCMD 4WCED 5MLCG 2WNYA 1YHQD 4IOAD 2NWUA 1YI2D 1K73F 4WF9D 1Q81F 3CCQD 1VQMD 5GAGF 1KC8F 1S72D 3CMAD 1VQ5D 1JJ2D 2QEXD 1VQ7D 1K8AF 2OGKA 1VQ9D 3CCUD 1M90F 5H1SH 5GADF 3CF5D 3CC4D 3G4SD 3G6ED 5GAHF 4U67D 4UY8F 1K9MF 1VQ8D 3CCLD 5HL7D 1W2BD 3PIOD 1M1KF 3OW2D 3CCRD 1KQSD 1YIJD 1VQND 1VQPD 1MJIA 1YITD 1VQ4D 5DM6D 5JVHD 3DLLD 4WFAD 2ZJQD 2OTLD 4IO9D 5JVGD 1VQ6D 5GAEF 3CXCD 1Q7YF 1QVGD 2ZJRD 1QVFD 2NRQA
chains in the Genus database with same CATH topology
1Q86F 1VQLD 4WFBD 3CCED 1YJND 3C9GA 3CC7D 3PIPD 1KD1F 2OTJD 1VQKD 1VQOD 3D7AA 3G71D 2ZJPD 1IQ4A 3CCVD 4WFND 5DM7D 2PZZA 1YJWD 1YJ9D 1N8RF 1NJIF 3CC2D 3I56D 2QA4D 4IOCD 3CCSD 1Q82F 3CPWD 3I55D 3CMED 3J7ZF 3CD6D 3CCJD 3CCMD 4WCED 5MLCG 2WNYA 1YHQD 4IOAD 2NWUA 1YI2D 1K73F 4WF9D 1Q81F 3CCQD 1VQMD 5GAGF 1KC8F 1S72D 3CMAD 1VQ5D 1JJ2D 2QEXD 1VQ7D 1K8AF 2OGKA 1VQ9D 3CCUD 1M90F 5H1SH 5GADF 3CF5D 3CC4D 3G4SD 3G6ED 5GAHF 4U67D 4UY8F 1K9MF 1VQ8D 3CCLD 5HL7D 1W2BD 3PIOD 1M1KF 3OW2D 3CCRD 1KQSD 1YIJD 1VQND 1VQPD 1MJIA 1YITD 1VQ4D 5DM6D 5JVHD 3DLLD 4WFAD 2ZJQD 2OTLD 4IO9D 5JVGD 1VQ6D 5GAEF 3CXCD 1Q7YF 1QVGD 2ZJRD 1QVFD 2NRQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q86 F;  1VQL D;  4WFB D;  3CCE D;  1YJN D;  3C9G A;  3CC7 D;  3PIP D;  1KD1 F;  2OTJ D;  1VQK D;  1VQO D;  3D7A A;  3G71 D;  2ZJP D;  1IQ4 A;  3CCV D;  4WFN D;  5DM7 D;  2PZZ A;  1YJW D;  1YJ9 D;  1N8R F;  1NJI F;  3CC2 D;  3I56 D;  2QA4 D;  4IOC D;  3CCS D;  1Q82 F;  3CPW D;  3I55 D;  3CME D;  3J7Z F;  3CD6 D;  3CCJ D;  3CCM D;  4WCE D;  5MLC G;  2WNY A;  1YHQ D;  4IOA D;  2NWU A;  1YI2 D;  1K73 F;  4WF9 D;  1Q81 F;  3CCQ D;  1VQM D;  5GAG F;  1KC8 F;  1S72 D;  3CMA D;  1VQ5 D;  1JJ2 D;  2QEX D;  1VQ7 D;  1K8A F;  2OGK A;  1VQ9 D;  3CCU D;  1M90 F;  5H1S H;  5GAD F;  3CF5 D;  3CC4 D;  3G4S D;  3G6E D;  5GAH F;  4U67 D;  4UY8 F;  1K9M F;  1VQ8 D;  3CCL D;  5HL7 D;  1W2B D;  3PIO D;  1M1K F;  3OW2 D;  3CCR D;  1KQS D;  1YIJ D;  1VQN D;  1VQP D;  1MJI A;  1YIT D;  1VQ4 D;  5DM6 D;  5JVH D;  3DLL D;  4WFA D;  2ZJQ D;  2OTL D;  4IO9 D;  5JVG D;  1VQ6 D;  5GAE F;  3CXC D;  1Q7Y F;  1QVG D;  2ZJR D;  1QVF D;  2NRQ A; 
#chains in the Genus database with same CATH topology
 1Q86 F;  1VQL D;  4WFB D;  3CCE D;  1YJN D;  3C9G A;  3CC7 D;  3PIP D;  1KD1 F;  2OTJ D;  1VQK D;  1VQO D;  3D7A A;  3G71 D;  2ZJP D;  1IQ4 A;  3CCV D;  4WFN D;  5DM7 D;  2PZZ A;  1YJW D;  1YJ9 D;  1N8R F;  1NJI F;  3CC2 D;  3I56 D;  2QA4 D;  4IOC D;  3CCS D;  1Q82 F;  3CPW D;  3I55 D;  3CME D;  3J7Z F;  3CD6 D;  3CCJ D;  3CCM D;  4WCE D;  5MLC G;  2WNY A;  1YHQ D;  4IOA D;  2NWU A;  1YI2 D;  1K73 F;  4WF9 D;  1Q81 F;  3CCQ D;  1VQM D;  5GAG F;  1KC8 F;  1S72 D;  3CMA D;  1VQ5 D;  1JJ2 D;  2QEX D;  1VQ7 D;  1K8A F;  2OGK A;  1VQ9 D;  3CCU D;  1M90 F;  5H1S H;  5GAD F;  3CF5 D;  3CC4 D;  3G4S D;  3G6E D;  5GAH F;  4U67 D;  4UY8 F;  1K9M F;  1VQ8 D;  3CCL D;  5HL7 D;  1W2B D;  3PIO D;  1M1K F;  3OW2 D;  3CCR D;  1KQS D;  1YIJ D;  1VQN D;  1VQP D;  1MJI A;  1YIT D;  1VQ4 D;  5DM6 D;  5JVH D;  3DLL D;  4WFA D;  2ZJQ D;  2OTL D;  4IO9 D;  5JVG D;  1VQ6 D;  5GAE F;  3CXC D;  1Q7Y F;  1QVG D;  2ZJR D;  1QVF D;  2NRQ A; 
#chains in the Genus database with same CATH homology
 1Q86 F;  1VQL D;  4WFB D;  3CCE D;  1YJN D;  3C9G A;  3CC7 D;  3PIP D;  1KD1 F;  2OTJ D;  1VQK D;  1VQO D;  3D7A A;  3G71 D;  2ZJP D;  1IQ4 A;  3CCV D;  4WFN D;  5DM7 D;  2PZZ A;  1YJW D;  1YJ9 D;  1N8R F;  1NJI F;  3CC2 D;  3I56 D;  2QA4 D;  4IOC D;  3CCS D;  1Q82 F;  3CPW D;  3I55 D;  3CME D;  3J7Z F;  3CD6 D;  3CCJ D;  3CCM D;  4WCE D;  5MLC G;  2WNY A;  1YHQ D;  4IOA D;  2NWU A;  1YI2 D;  1K73 F;  4WF9 D;  1Q81 F;  3CCQ D;  1VQM D;  5GAG F;  1KC8 F;  1S72 D;  3CMA D;  1VQ5 D;  1JJ2 D;  2QEX D;  1VQ7 D;  1K8A F;  2OGK A;  1VQ9 D;  3CCU D;  1M90 F;  5H1S H;  5GAD F;  3CF5 D;  3CC4 D;  3G4S D;  3G6E D;  5GAH F;  4U67 D;  4UY8 F;  1K9M F;  1VQ8 D;  3CCL D;  5HL7 D;  1W2B D;  3PIO D;  1M1K F;  3OW2 D;  3CCR D;  1KQS D;  1YIJ D;  1VQN D;  1VQP D;  1MJI A;  1YIT D;  1VQ4 D;  5DM6 D;  5JVH D;  3DLL D;  4WFA D;  2ZJQ D;  2OTL D;  4IO9 D;  5JVG D;  1VQ6 D;  5GAE F;  3CXC D;  1Q7Y F;  1QVG D;  2ZJR D;  1QVF D;  2NRQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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