3CCQD

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488u
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 17
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3ccqD00
1M1KF 1K8AF 1YJWD 5JVHD 3PIPD 2NRQA 3I56D 3PIOD 1VQ5D 1Q86F 1VQ6D 1MJIA 4WFND 1KC8F 5DM7D 4WFAD 1Q7YF 1VQKD 4WCED 1YHQD 3C9GA 1IQ4A 1YI2D 3CPWD 1M90F 5GAGF 5GADF 1VQPD 3CCMD 1K9MF 1YIJD 3CCQD 1VQ8D 5DM6D 3G4SD 2ZJRD 3I55D 2ZJPD 3CCRD 1JJ2D 2PZZA 1VQ9D 4IOAD 5HL7D 3G71D 1NJIF 5JVGD 2QEXD 1KD1F 5GAEF 4U67D 3CXCD 1VQLD 2WNYA 3CMAD 1VQOD 1YJ9D 3CCVD 1Q81F 3CCED 5H1SH 4UY8F 3CCUD 4IO9D 5MLCG 3DLLD 1VQND 3D7AA 3CC7D 1YJND 1QVGD 3G6ED 1VQMD 3J7ZF 1Q82F 1W2BD 2QA4D 1YITD 3CMED 1VQ7D 4WFBD 1KQSD 3CCLD 1QVFD 4IOCD 2OTJD 2OGKA 1S72D 3CCJD 1VQ4D 2OTLD 2NWUA 3CF5D 3CCSD 3CC2D 3OW2D 2ZJQD 5GAHF 4WF9D 1K73F 3CC4D 3CD6D 1N8RF
chains in the Genus database with same CATH superfamily
1M1KF 1K8AF 1YJWD 5JVHD 3PIPD 2NRQA 3I56D 3PIOD 1VQ5D 1Q86F 1VQ6D 1MJIA 4WFND 1KC8F 5DM7D 4WFAD 1Q7YF 1VQKD 4WCED 1YHQD 3C9GA 1IQ4A 1YI2D 3CPWD 1M90F 5GAGF 5GADF 1VQPD 3CCMD 1K9MF 1YIJD 3CCQD 1VQ8D 5DM6D 3G4SD 2ZJRD 3I55D 2ZJPD 3CCRD 1JJ2D 2PZZA 1VQ9D 4IOAD 5HL7D 3G71D 1NJIF 5JVGD 2QEXD 1KD1F 5GAEF 4U67D 3CXCD 1VQLD 2WNYA 3CMAD 1VQOD 1YJ9D 3CCVD 1Q81F 3CCED 5H1SH 4UY8F 3CCUD 4IO9D 5MLCG 3DLLD 1VQND 3D7AA 3CC7D 1YJND 1QVGD 3G6ED 1VQMD 3J7ZF 1Q82F 1W2BD 2QA4D 1YITD 3CMED 1VQ7D 4WFBD 1KQSD 3CCLD 1QVFD 4IOCD 2OTJD 2OGKA 1S72D 3CCJD 1VQ4D 2OTLD 2NWUA 3CF5D 3CCSD 3CC2D 3OW2D 2ZJQD 5GAHF 4WF9D 1K73F 3CC4D 3CD6D 1N8RF
chains in the Genus database with same CATH topology
1M1KF 1K8AF 1YJWD 5JVHD 3PIPD 2NRQA 3I56D 3PIOD 1VQ5D 1Q86F 1VQ6D 1MJIA 4WFND 1KC8F 5DM7D 4WFAD 1Q7YF 1VQKD 4WCED 1YHQD 3C9GA 1IQ4A 1YI2D 3CPWD 1M90F 5GAGF 5GADF 1VQPD 3CCMD 1K9MF 1YIJD 3CCQD 1VQ8D 5DM6D 3G4SD 2ZJRD 3I55D 2ZJPD 3CCRD 1JJ2D 2PZZA 1VQ9D 4IOAD 5HL7D 3G71D 1NJIF 5JVGD 2QEXD 1KD1F 5GAEF 4U67D 3CXCD 1VQLD 2WNYA 3CMAD 1VQOD 1YJ9D 3CCVD 1Q81F 3CCED 5H1SH 4UY8F 3CCUD 4IO9D 5MLCG 3DLLD 1VQND 3D7AA 3CC7D 1YJND 1QVGD 3G6ED 1VQMD 3J7ZF 1Q82F 1W2BD 2QA4D 1YITD 3CMED 1VQ7D 4WFBD 1KQSD 3CCLD 1QVFD 4IOCD 2OTJD 2OGKA 1S72D 3CCJD 1VQ4D 2OTLD 2NWUA 3CF5D 3CCSD 3CC2D 3OW2D 2ZJQD 5GAHF 4WF9D 1K73F 3CC4D 3CD6D 1N8RF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M1K F;  1K8A F;  1YJW D;  5JVH D;  3PIP D;  2NRQ A;  3I56 D;  3PIO D;  1VQ5 D;  1Q86 F;  1VQ6 D;  1MJI A;  4WFN D;  1KC8 F;  5DM7 D;  4WFA D;  1Q7Y F;  1VQK D;  4WCE D;  1YHQ D;  3C9G A;  1IQ4 A;  1YI2 D;  3CPW D;  1M90 F;  5GAG F;  5GAD F;  1VQP D;  3CCM D;  1K9M F;  1YIJ D;  3CCQ D;  1VQ8 D;  5DM6 D;  3G4S D;  2ZJR D;  3I55 D;  2ZJP D;  3CCR D;  1JJ2 D;  2PZZ A;  1VQ9 D;  4IOA D;  5HL7 D;  3G71 D;  1NJI F;  5JVG D;  2QEX D;  1KD1 F;  5GAE F;  4U67 D;  3CXC D;  1VQL D;  2WNY A;  3CMA D;  1VQO D;  1YJ9 D;  3CCV D;  1Q81 F;  3CCE D;  5H1S H;  4UY8 F;  3CCU D;  4IO9 D;  5MLC G;  3DLL D;  1VQN D;  3D7A A;  3CC7 D;  1YJN D;  1QVG D;  3G6E D;  1VQM D;  3J7Z F;  1Q82 F;  1W2B D;  2QA4 D;  1YIT D;  3CME D;  1VQ7 D;  4WFB D;  1KQS D;  3CCL D;  1QVF D;  4IOC D;  2OTJ D;  2OGK A;  1S72 D;  3CCJ D;  1VQ4 D;  2OTL D;  2NWU A;  3CF5 D;  3CCS D;  3CC2 D;  3OW2 D;  2ZJQ D;  5GAH F;  4WF9 D;  1K73 F;  3CC4 D;  3CD6 D;  1N8R F; 
#chains in the Genus database with same CATH topology
 1M1K F;  1K8A F;  1YJW D;  5JVH D;  3PIP D;  2NRQ A;  3I56 D;  3PIO D;  1VQ5 D;  1Q86 F;  1VQ6 D;  1MJI A;  4WFN D;  1KC8 F;  5DM7 D;  4WFA D;  1Q7Y F;  1VQK D;  4WCE D;  1YHQ D;  3C9G A;  1IQ4 A;  1YI2 D;  3CPW D;  1M90 F;  5GAG F;  5GAD F;  1VQP D;  3CCM D;  1K9M F;  1YIJ D;  3CCQ D;  1VQ8 D;  5DM6 D;  3G4S D;  2ZJR D;  3I55 D;  2ZJP D;  3CCR D;  1JJ2 D;  2PZZ A;  1VQ9 D;  4IOA D;  5HL7 D;  3G71 D;  1NJI F;  5JVG D;  2QEX D;  1KD1 F;  5GAE F;  4U67 D;  3CXC D;  1VQL D;  2WNY A;  3CMA D;  1VQO D;  1YJ9 D;  3CCV D;  1Q81 F;  3CCE D;  5H1S H;  4UY8 F;  3CCU D;  4IO9 D;  5MLC G;  3DLL D;  1VQN D;  3D7A A;  3CC7 D;  1YJN D;  1QVG D;  3G6E D;  1VQM D;  3J7Z F;  1Q82 F;  1W2B D;  2QA4 D;  1YIT D;  3CME D;  1VQ7 D;  4WFB D;  1KQS D;  3CCL D;  1QVF D;  4IOC D;  2OTJ D;  2OGK A;  1S72 D;  3CCJ D;  1VQ4 D;  2OTL D;  2NWU A;  3CF5 D;  3CCS D;  3CC2 D;  3OW2 D;  2ZJQ D;  5GAH F;  4WF9 D;  1K73 F;  3CC4 D;  3CD6 D;  1N8R F; 
#chains in the Genus database with same CATH homology
 1M1K F;  1K8A F;  1YJW D;  5JVH D;  3PIP D;  2NRQ A;  3I56 D;  3PIO D;  1VQ5 D;  1Q86 F;  1VQ6 D;  1MJI A;  4WFN D;  1KC8 F;  5DM7 D;  4WFA D;  1Q7Y F;  1VQK D;  4WCE D;  1YHQ D;  3C9G A;  1IQ4 A;  1YI2 D;  3CPW D;  1M90 F;  5GAG F;  5GAD F;  1VQP D;  3CCM D;  1K9M F;  1YIJ D;  3CCQ D;  1VQ8 D;  5DM6 D;  3G4S D;  2ZJR D;  3I55 D;  2ZJP D;  3CCR D;  1JJ2 D;  2PZZ A;  1VQ9 D;  4IOA D;  5HL7 D;  3G71 D;  1NJI F;  5JVG D;  2QEX D;  1KD1 F;  5GAE F;  4U67 D;  3CXC D;  1VQL D;  2WNY A;  3CMA D;  1VQO D;  1YJ9 D;  3CCV D;  1Q81 F;  3CCE D;  5H1S H;  4UY8 F;  3CCU D;  4IO9 D;  5MLC G;  3DLL D;  1VQN D;  3D7A A;  3CC7 D;  1YJN D;  1QVG D;  3G6E D;  1VQM D;  3J7Z F;  1Q82 F;  1W2B D;  2QA4 D;  1YIT D;  3CME D;  1VQ7 D;  4WFB D;  1KQS D;  3CCL D;  1QVF D;  4IOC D;  2OTJ D;  2OGK A;  1S72 D;  3CCJ D;  1VQ4 D;  2OTL D;  2NWU A;  3CF5 D;  3CCS D;  3CC2 D;  3OW2 D;  2ZJQ D;  5GAH F;  4WF9 D;  1K73 F;  3CC4 D;  3CD6 D;  1N8R F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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