3CCRD

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation a2488c. density for anisomycin is visible but not included in the model.
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 19
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3ccrD00
1YHQD 3CMED 2OTLD 1QVGD 4WFND 5JVGD 1VQKD 1K73F 5MLCG 5GAEF 3D7AA 1Q82F 1Q81F 2ZJPD 2NWUA 4WF9D 3C9GA 3CXCD 3OW2D 2ZJQD 1VQ4D 3PIOD 3G6ED 5DM6D 1IQ4A 3CCQD 5DM7D 3I55D 4IOAD 3CCLD 3G4SD 3CC7D 1KD1F 3CCRD 4UY8F 1Q86F 3CMAD 1YIJD 1KC8F 5HL7D 1M90F 3CCVD 1YJ9D 3CCJD 1VQLD 3CCSD 1YJND 1NJIF 1VQ8D 1N8RF 2OTJD 1QVFD 5JVHD 3G71D 3CCUD 1K9MF 1VQOD 1Q7YF 4IO9D 3DLLD 1YI2D 4WCED 1MJIA 1YJWD 1VQMD 1VQPD 5GADF 3CC2D 1M1KF 3CC4D 5H1SH 3I56D 1VQ9D 1KQSD 4IOCD 3CCMD 1W2BD 1YITD 1K8AF 1VQ5D 2ZJRD 5GAGF 3CF5D 1S72D 2NRQA 2WNYA 3CCED 2PZZA 3CD6D 2QA4D 2OGKA 4U67D 1VQ6D 4WFAD 3CPWD 4WFBD 5GAHF 2QEXD 1VQND 3PIPD 1VQ7D 3J7ZF 1JJ2D
chains in the Genus database with same CATH superfamily
1YHQD 3CMED 2OTLD 1QVGD 4WFND 5JVGD 1VQKD 1K73F 5MLCG 5GAEF 3D7AA 1Q82F 1Q81F 2ZJPD 2NWUA 4WF9D 3C9GA 3CXCD 3OW2D 2ZJQD 1VQ4D 3PIOD 3G6ED 5DM6D 1IQ4A 3CCQD 5DM7D 3I55D 4IOAD 3CCLD 3G4SD 3CC7D 1KD1F 3CCRD 4UY8F 1Q86F 3CMAD 1YIJD 1KC8F 5HL7D 1M90F 3CCVD 1YJ9D 3CCJD 1VQLD 3CCSD 1YJND 1NJIF 1VQ8D 1N8RF 2OTJD 1QVFD 5JVHD 3G71D 3CCUD 1K9MF 1VQOD 1Q7YF 4IO9D 3DLLD 1YI2D 4WCED 1MJIA 1YJWD 1VQMD 1VQPD 5GADF 3CC2D 1M1KF 3CC4D 5H1SH 3I56D 1VQ9D 1KQSD 4IOCD 3CCMD 1W2BD 1YITD 1K8AF 1VQ5D 2ZJRD 5GAGF 3CF5D 1S72D 2NRQA 2WNYA 3CCED 2PZZA 3CD6D 2QA4D 2OGKA 4U67D 1VQ6D 4WFAD 3CPWD 4WFBD 5GAHF 2QEXD 1VQND 3PIPD 1VQ7D 3J7ZF 1JJ2D
chains in the Genus database with same CATH topology
1YHQD 3CMED 2OTLD 1QVGD 4WFND 5JVGD 1VQKD 1K73F 5MLCG 5GAEF 3D7AA 1Q82F 1Q81F 2ZJPD 2NWUA 4WF9D 3C9GA 3CXCD 3OW2D 2ZJQD 1VQ4D 3PIOD 3G6ED 5DM6D 1IQ4A 3CCQD 5DM7D 3I55D 4IOAD 3CCLD 3G4SD 3CC7D 1KD1F 3CCRD 4UY8F 1Q86F 3CMAD 1YIJD 1KC8F 5HL7D 1M90F 3CCVD 1YJ9D 3CCJD 1VQLD 3CCSD 1YJND 1NJIF 1VQ8D 1N8RF 2OTJD 1QVFD 5JVHD 3G71D 3CCUD 1K9MF 1VQOD 1Q7YF 4IO9D 3DLLD 1YI2D 4WCED 1MJIA 1YJWD 1VQMD 1VQPD 5GADF 3CC2D 1M1KF 3CC4D 5H1SH 3I56D 1VQ9D 1KQSD 4IOCD 3CCMD 1W2BD 1YITD 1K8AF 1VQ5D 2ZJRD 5GAGF 3CF5D 1S72D 2NRQA 2WNYA 3CCED 2PZZA 3CD6D 2QA4D 2OGKA 4U67D 1VQ6D 4WFAD 3CPWD 4WFBD 5GAHF 2QEXD 1VQND 3PIPD 1VQ7D 3J7ZF 1JJ2D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YHQ D;  3CME D;  2OTL D;  1QVG D;  4WFN D;  5JVG D;  1VQK D;  1K73 F;  5MLC G;  5GAE F;  3D7A A;  1Q82 F;  1Q81 F;  2ZJP D;  2NWU A;  4WF9 D;  3C9G A;  3CXC D;  3OW2 D;  2ZJQ D;  1VQ4 D;  3PIO D;  3G6E D;  5DM6 D;  1IQ4 A;  3CCQ D;  5DM7 D;  3I55 D;  4IOA D;  3CCL D;  3G4S D;  3CC7 D;  1KD1 F;  3CCR D;  4UY8 F;  1Q86 F;  3CMA D;  1YIJ D;  1KC8 F;  5HL7 D;  1M90 F;  3CCV D;  1YJ9 D;  3CCJ D;  1VQL D;  3CCS D;  1YJN D;  1NJI F;  1VQ8 D;  1N8R F;  2OTJ D;  1QVF D;  5JVH D;  3G71 D;  3CCU D;  1K9M F;  1VQO D;  1Q7Y F;  4IO9 D;  3DLL D;  1YI2 D;  4WCE D;  1MJI A;  1YJW D;  1VQM D;  1VQP D;  5GAD F;  3CC2 D;  1M1K F;  3CC4 D;  5H1S H;  3I56 D;  1VQ9 D;  1KQS D;  4IOC D;  3CCM D;  1W2B D;  1YIT D;  1K8A F;  1VQ5 D;  2ZJR D;  5GAG F;  3CF5 D;  1S72 D;  2NRQ A;  2WNY A;  3CCE D;  2PZZ A;  3CD6 D;  2QA4 D;  2OGK A;  4U67 D;  1VQ6 D;  4WFA D;  3CPW D;  4WFB D;  5GAH F;  2QEX D;  1VQN D;  3PIP D;  1VQ7 D;  3J7Z F;  1JJ2 D; 
#chains in the Genus database with same CATH topology
 1YHQ D;  3CME D;  2OTL D;  1QVG D;  4WFN D;  5JVG D;  1VQK D;  1K73 F;  5MLC G;  5GAE F;  3D7A A;  1Q82 F;  1Q81 F;  2ZJP D;  2NWU A;  4WF9 D;  3C9G A;  3CXC D;  3OW2 D;  2ZJQ D;  1VQ4 D;  3PIO D;  3G6E D;  5DM6 D;  1IQ4 A;  3CCQ D;  5DM7 D;  3I55 D;  4IOA D;  3CCL D;  3G4S D;  3CC7 D;  1KD1 F;  3CCR D;  4UY8 F;  1Q86 F;  3CMA D;  1YIJ D;  1KC8 F;  5HL7 D;  1M90 F;  3CCV D;  1YJ9 D;  3CCJ D;  1VQL D;  3CCS D;  1YJN D;  1NJI F;  1VQ8 D;  1N8R F;  2OTJ D;  1QVF D;  5JVH D;  3G71 D;  3CCU D;  1K9M F;  1VQO D;  1Q7Y F;  4IO9 D;  3DLL D;  1YI2 D;  4WCE D;  1MJI A;  1YJW D;  1VQM D;  1VQP D;  5GAD F;  3CC2 D;  1M1K F;  3CC4 D;  5H1S H;  3I56 D;  1VQ9 D;  1KQS D;  4IOC D;  3CCM D;  1W2B D;  1YIT D;  1K8A F;  1VQ5 D;  2ZJR D;  5GAG F;  3CF5 D;  1S72 D;  2NRQ A;  2WNY A;  3CCE D;  2PZZ A;  3CD6 D;  2QA4 D;  2OGK A;  4U67 D;  1VQ6 D;  4WFA D;  3CPW D;  4WFB D;  5GAH F;  2QEX D;  1VQN D;  3PIP D;  1VQ7 D;  3J7Z F;  1JJ2 D; 
#chains in the Genus database with same CATH homology
 1YHQ D;  3CME D;  2OTL D;  1QVG D;  4WFN D;  5JVG D;  1VQK D;  1K73 F;  5MLC G;  5GAE F;  3D7A A;  1Q82 F;  1Q81 F;  2ZJP D;  2NWU A;  4WF9 D;  3C9G A;  3CXC D;  3OW2 D;  2ZJQ D;  1VQ4 D;  3PIO D;  3G6E D;  5DM6 D;  1IQ4 A;  3CCQ D;  5DM7 D;  3I55 D;  4IOA D;  3CCL D;  3G4S D;  3CC7 D;  1KD1 F;  3CCR D;  4UY8 F;  1Q86 F;  3CMA D;  1YIJ D;  1KC8 F;  5HL7 D;  1M90 F;  3CCV D;  1YJ9 D;  3CCJ D;  1VQL D;  3CCS D;  1YJN D;  1NJI F;  1VQ8 D;  1N8R F;  2OTJ D;  1QVF D;  5JVH D;  3G71 D;  3CCU D;  1K9M F;  1VQO D;  1Q7Y F;  4IO9 D;  3DLL D;  1YI2 D;  4WCE D;  1MJI A;  1YJW D;  1VQM D;  1VQP D;  5GAD F;  3CC2 D;  1M1K F;  3CC4 D;  5H1S H;  3I56 D;  1VQ9 D;  1KQS D;  4IOC D;  3CCM D;  1W2B D;  1YIT D;  1K8A F;  1VQ5 D;  2ZJR D;  5GAG F;  3CF5 D;  1S72 D;  2NRQ A;  2WNY A;  3CCE D;  2PZZ A;  3CD6 D;  2QA4 D;  2OGK A;  4U67 D;  1VQ6 D;  4WFA D;  3CPW D;  4WFB D;  5GAH F;  2QEX D;  1VQN D;  3PIP D;  1VQ7 D;  3J7Z F;  1JJ2 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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