3CCSD

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482a
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 17
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3ccsD00
1VQ8D 1Q81F 5HL7D 1VQLD 1IQ4A 3DLLD 5DM6D 3PIOD 3G4SD 3CMAD 5H1SH 2OTLD 4WF9D 2QEXD 1YJND 1VQ6D 2QA4D 2PZZA 3CCRD 1VQMD 1YJ9D 1VQKD 4WFBD 4IOAD 3I56D 1KD1F 3I55D 5DM7D 3G6ED 1M90F 5GAEF 4UY8F 1YHQD 4WFAD 1MJIA 2OTJD 1YIJD 1KQSD 5JVHD 1S72D 3CCJD 1VQPD 4U67D 3CCMD 3CC7D 4WCED 3G71D 3CCUD 1VQOD 5GADF 1N8RF 3CCVD 3CXCD 3CD6D 3C9GA 1VQ9D 1K9MF 1QVFD 3J7ZF 3D7AA 1Q7YF 1K73F 1W2BD 1VQND 5GAGF 3OW2D 1M1KF 3CMED 1YITD 1QVGD 2NWUA 1YJWD 2WNYA 2ZJPD 3CF5D 3CCQD 1VQ7D 2OGKA 3CCSD 5MLCG 1VQ5D 1Q82F 3PIPD 1YI2D 3CCLD 2ZJRD 1JJ2D 4IO9D 1NJIF 3CC4D 1KC8F 4WFND 1VQ4D 3CCED 3CPWD 4IOCD 1K8AF 3CC2D 2ZJQD 2NRQA 5GAHF 1Q86F 5JVGD
chains in the Genus database with same CATH superfamily
1VQ8D 1Q81F 5HL7D 1VQLD 1IQ4A 3DLLD 5DM6D 3PIOD 3G4SD 3CMAD 5H1SH 2OTLD 4WF9D 2QEXD 1YJND 1VQ6D 2QA4D 2PZZA 3CCRD 1VQMD 1YJ9D 1VQKD 4WFBD 4IOAD 3I56D 1KD1F 3I55D 5DM7D 3G6ED 1M90F 5GAEF 4UY8F 1YHQD 4WFAD 1MJIA 2OTJD 1YIJD 1KQSD 5JVHD 1S72D 3CCJD 1VQPD 4U67D 3CCMD 3CC7D 4WCED 3G71D 3CCUD 1VQOD 5GADF 1N8RF 3CCVD 3CXCD 3CD6D 3C9GA 1VQ9D 1K9MF 1QVFD 3J7ZF 3D7AA 1Q7YF 1K73F 1W2BD 1VQND 5GAGF 3OW2D 1M1KF 3CMED 1YITD 1QVGD 2NWUA 1YJWD 2WNYA 2ZJPD 3CF5D 3CCQD 1VQ7D 2OGKA 3CCSD 5MLCG 1VQ5D 1Q82F 3PIPD 1YI2D 3CCLD 2ZJRD 1JJ2D 4IO9D 1NJIF 3CC4D 1KC8F 4WFND 1VQ4D 3CCED 3CPWD 4IOCD 1K8AF 3CC2D 2ZJQD 2NRQA 5GAHF 1Q86F 5JVGD
chains in the Genus database with same CATH topology
1VQ8D 1Q81F 5HL7D 1VQLD 1IQ4A 3DLLD 5DM6D 3PIOD 3G4SD 3CMAD 5H1SH 2OTLD 4WF9D 2QEXD 1YJND 1VQ6D 2QA4D 2PZZA 3CCRD 1VQMD 1YJ9D 1VQKD 4WFBD 4IOAD 3I56D 1KD1F 3I55D 5DM7D 3G6ED 1M90F 5GAEF 4UY8F 1YHQD 4WFAD 1MJIA 2OTJD 1YIJD 1KQSD 5JVHD 1S72D 3CCJD 1VQPD 4U67D 3CCMD 3CC7D 4WCED 3G71D 3CCUD 1VQOD 5GADF 1N8RF 3CCVD 3CXCD 3CD6D 3C9GA 1VQ9D 1K9MF 1QVFD 3J7ZF 3D7AA 1Q7YF 1K73F 1W2BD 1VQND 5GAGF 3OW2D 1M1KF 3CMED 1YITD 1QVGD 2NWUA 1YJWD 2WNYA 2ZJPD 3CF5D 3CCQD 1VQ7D 2OGKA 3CCSD 5MLCG 1VQ5D 1Q82F 3PIPD 1YI2D 3CCLD 2ZJRD 1JJ2D 4IO9D 1NJIF 3CC4D 1KC8F 4WFND 1VQ4D 3CCED 3CPWD 4IOCD 1K8AF 3CC2D 2ZJQD 2NRQA 5GAHF 1Q86F 5JVGD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQ8 D;  1Q81 F;  5HL7 D;  1VQL D;  1IQ4 A;  3DLL D;  5DM6 D;  3PIO D;  3G4S D;  3CMA D;  5H1S H;  2OTL D;  4WF9 D;  2QEX D;  1YJN D;  1VQ6 D;  2QA4 D;  2PZZ A;  3CCR D;  1VQM D;  1YJ9 D;  1VQK D;  4WFB D;  4IOA D;  3I56 D;  1KD1 F;  3I55 D;  5DM7 D;  3G6E D;  1M90 F;  5GAE F;  4UY8 F;  1YHQ D;  4WFA D;  1MJI A;  2OTJ D;  1YIJ D;  1KQS D;  5JVH D;  1S72 D;  3CCJ D;  1VQP D;  4U67 D;  3CCM D;  3CC7 D;  4WCE D;  3G71 D;  3CCU D;  1VQO D;  5GAD F;  1N8R F;  3CCV D;  3CXC D;  3CD6 D;  3C9G A;  1VQ9 D;  1K9M F;  1QVF D;  3J7Z F;  3D7A A;  1Q7Y F;  1K73 F;  1W2B D;  1VQN D;  5GAG F;  3OW2 D;  1M1K F;  3CME D;  1YIT D;  1QVG D;  2NWU A;  1YJW D;  2WNY A;  2ZJP D;  3CF5 D;  3CCQ D;  1VQ7 D;  2OGK A;  3CCS D;  5MLC G;  1VQ5 D;  1Q82 F;  3PIP D;  1YI2 D;  3CCL D;  2ZJR D;  1JJ2 D;  4IO9 D;  1NJI F;  3CC4 D;  1KC8 F;  4WFN D;  1VQ4 D;  3CCE D;  3CPW D;  4IOC D;  1K8A F;  3CC2 D;  2ZJQ D;  2NRQ A;  5GAH F;  1Q86 F;  5JVG D; 
#chains in the Genus database with same CATH topology
 1VQ8 D;  1Q81 F;  5HL7 D;  1VQL D;  1IQ4 A;  3DLL D;  5DM6 D;  3PIO D;  3G4S D;  3CMA D;  5H1S H;  2OTL D;  4WF9 D;  2QEX D;  1YJN D;  1VQ6 D;  2QA4 D;  2PZZ A;  3CCR D;  1VQM D;  1YJ9 D;  1VQK D;  4WFB D;  4IOA D;  3I56 D;  1KD1 F;  3I55 D;  5DM7 D;  3G6E D;  1M90 F;  5GAE F;  4UY8 F;  1YHQ D;  4WFA D;  1MJI A;  2OTJ D;  1YIJ D;  1KQS D;  5JVH D;  1S72 D;  3CCJ D;  1VQP D;  4U67 D;  3CCM D;  3CC7 D;  4WCE D;  3G71 D;  3CCU D;  1VQO D;  5GAD F;  1N8R F;  3CCV D;  3CXC D;  3CD6 D;  3C9G A;  1VQ9 D;  1K9M F;  1QVF D;  3J7Z F;  3D7A A;  1Q7Y F;  1K73 F;  1W2B D;  1VQN D;  5GAG F;  3OW2 D;  1M1K F;  3CME D;  1YIT D;  1QVG D;  2NWU A;  1YJW D;  2WNY A;  2ZJP D;  3CF5 D;  3CCQ D;  1VQ7 D;  2OGK A;  3CCS D;  5MLC G;  1VQ5 D;  1Q82 F;  3PIP D;  1YI2 D;  3CCL D;  2ZJR D;  1JJ2 D;  4IO9 D;  1NJI F;  3CC4 D;  1KC8 F;  4WFN D;  1VQ4 D;  3CCE D;  3CPW D;  4IOC D;  1K8A F;  3CC2 D;  2ZJQ D;  2NRQ A;  5GAH F;  1Q86 F;  5JVG D; 
#chains in the Genus database with same CATH homology
 1VQ8 D;  1Q81 F;  5HL7 D;  1VQL D;  1IQ4 A;  3DLL D;  5DM6 D;  3PIO D;  3G4S D;  3CMA D;  5H1S H;  2OTL D;  4WF9 D;  2QEX D;  1YJN D;  1VQ6 D;  2QA4 D;  2PZZ A;  3CCR D;  1VQM D;  1YJ9 D;  1VQK D;  4WFB D;  4IOA D;  3I56 D;  1KD1 F;  3I55 D;  5DM7 D;  3G6E D;  1M90 F;  5GAE F;  4UY8 F;  1YHQ D;  4WFA D;  1MJI A;  2OTJ D;  1YIJ D;  1KQS D;  5JVH D;  1S72 D;  3CCJ D;  1VQP D;  4U67 D;  3CCM D;  3CC7 D;  4WCE D;  3G71 D;  3CCU D;  1VQO D;  5GAD F;  1N8R F;  3CCV D;  3CXC D;  3CD6 D;  3C9G A;  1VQ9 D;  1K9M F;  1QVF D;  3J7Z F;  3D7A A;  1Q7Y F;  1K73 F;  1W2B D;  1VQN D;  5GAG F;  3OW2 D;  1M1K F;  3CME D;  1YIT D;  1QVG D;  2NWU A;  1YJW D;  2WNY A;  2ZJP D;  3CF5 D;  3CCQ D;  1VQ7 D;  2OGK A;  3CCS D;  5MLC G;  1VQ5 D;  1Q82 F;  3PIP D;  1YI2 D;  3CCL D;  2ZJR D;  1JJ2 D;  4IO9 D;  1NJI F;  3CC4 D;  1KC8 F;  4WFN D;  1VQ4 D;  3CCE D;  3CPW D;  4IOC D;  1K8A F;  3CC2 D;  2ZJQ D;  2NRQ A;  5GAH F;  1Q86 F;  5JVG D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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