3CCUD

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2482c
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 19
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3ccuD00
1YITD 3D7AA 2OTJD 1VQ5D 2QA4D 5GADF 3CMED 1VQMD 1YJND 1KC8F 5JVHD 1VQ8D 1Q81F 5DM6D 1KQSD 3CXCD 2ZJRD 1IQ4A 3CCLD 1M90F 1YHQD 3CCVD 1VQ9D 1VQPD 3C9GA 1YIJD 3CCJD 5GAGF 4WCED 3CCRD 3CC2D 2OGKA 3G71D 5GAHF 3CCQD 1Q7YF 1Q86F 4WFBD 4WFND 1VQ7D 1K8AF 5H1SH 1VQOD 3CPWD 2PZZA 1VQ6D 4UY8F 1VQLD 3CCSD 4WF9D 2NRQA 3PIOD 4IO9D 1YJWD 1QVGD 1M1KF 2QEXD 1N8RF 3CF5D 1VQ4D 2ZJPD 5JVGD 3CC4D 1VQND 2OTLD 2NWUA 5DM7D 3CCMD 3CCUD 3CD6D 3DLLD 4U67D 1K9MF 3G6ED 3PIPD 1JJ2D 1W2BD 5GAEF 1KD1F 3CCED 1Q82F 3CMAD 4IOCD 3I56D 3CC7D 3OW2D 2WNYA 1YJ9D 1K73F 5MLCG 1NJIF 4IOAD 1VQKD 2ZJQD 5HL7D 1S72D 3G4SD 1QVFD 1MJIA 1YI2D 3J7ZF 4WFAD 3I55D
chains in the Genus database with same CATH superfamily
1YITD 3D7AA 2OTJD 1VQ5D 2QA4D 5GADF 3CMED 1VQMD 1YJND 1KC8F 5JVHD 1VQ8D 1Q81F 5DM6D 1KQSD 3CXCD 2ZJRD 1IQ4A 3CCLD 1M90F 1YHQD 3CCVD 1VQ9D 1VQPD 3C9GA 1YIJD 3CCJD 5GAGF 4WCED 3CCRD 3CC2D 2OGKA 3G71D 5GAHF 3CCQD 1Q7YF 1Q86F 4WFBD 4WFND 1VQ7D 1K8AF 5H1SH 1VQOD 3CPWD 2PZZA 1VQ6D 4UY8F 1VQLD 3CCSD 4WF9D 2NRQA 3PIOD 4IO9D 1YJWD 1QVGD 1M1KF 2QEXD 1N8RF 3CF5D 1VQ4D 2ZJPD 5JVGD 3CC4D 1VQND 2OTLD 2NWUA 5DM7D 3CCMD 3CCUD 3CD6D 3DLLD 4U67D 1K9MF 3G6ED 3PIPD 1JJ2D 1W2BD 5GAEF 1KD1F 3CCED 1Q82F 3CMAD 4IOCD 3I56D 3CC7D 3OW2D 2WNYA 1YJ9D 1K73F 5MLCG 1NJIF 4IOAD 1VQKD 2ZJQD 5HL7D 1S72D 3G4SD 1QVFD 1MJIA 1YI2D 3J7ZF 4WFAD 3I55D
chains in the Genus database with same CATH topology
1YITD 3D7AA 2OTJD 1VQ5D 2QA4D 5GADF 3CMED 1VQMD 1YJND 1KC8F 5JVHD 1VQ8D 1Q81F 5DM6D 1KQSD 3CXCD 2ZJRD 1IQ4A 3CCLD 1M90F 1YHQD 3CCVD 1VQ9D 1VQPD 3C9GA 1YIJD 3CCJD 5GAGF 4WCED 3CCRD 3CC2D 2OGKA 3G71D 5GAHF 3CCQD 1Q7YF 1Q86F 4WFBD 4WFND 1VQ7D 1K8AF 5H1SH 1VQOD 3CPWD 2PZZA 1VQ6D 4UY8F 1VQLD 3CCSD 4WF9D 2NRQA 3PIOD 4IO9D 1YJWD 1QVGD 1M1KF 2QEXD 1N8RF 3CF5D 1VQ4D 2ZJPD 5JVGD 3CC4D 1VQND 2OTLD 2NWUA 5DM7D 3CCMD 3CCUD 3CD6D 3DLLD 4U67D 1K9MF 3G6ED 3PIPD 1JJ2D 1W2BD 5GAEF 1KD1F 3CCED 1Q82F 3CMAD 4IOCD 3I56D 3CC7D 3OW2D 2WNYA 1YJ9D 1K73F 5MLCG 1NJIF 4IOAD 1VQKD 2ZJQD 5HL7D 1S72D 3G4SD 1QVFD 1MJIA 1YI2D 3J7ZF 4WFAD 3I55D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YIT D;  3D7A A;  2OTJ D;  1VQ5 D;  2QA4 D;  5GAD F;  3CME D;  1VQM D;  1YJN D;  1KC8 F;  5JVH D;  1VQ8 D;  1Q81 F;  5DM6 D;  1KQS D;  3CXC D;  2ZJR D;  1IQ4 A;  3CCL D;  1M90 F;  1YHQ D;  3CCV D;  1VQ9 D;  1VQP D;  3C9G A;  1YIJ D;  3CCJ D;  5GAG F;  4WCE D;  3CCR D;  3CC2 D;  2OGK A;  3G71 D;  5GAH F;  3CCQ D;  1Q7Y F;  1Q86 F;  4WFB D;  4WFN D;  1VQ7 D;  1K8A F;  5H1S H;  1VQO D;  3CPW D;  2PZZ A;  1VQ6 D;  4UY8 F;  1VQL D;  3CCS D;  4WF9 D;  2NRQ A;  3PIO D;  4IO9 D;  1YJW D;  1QVG D;  1M1K F;  2QEX D;  1N8R F;  3CF5 D;  1VQ4 D;  2ZJP D;  5JVG D;  3CC4 D;  1VQN D;  2OTL D;  2NWU A;  5DM7 D;  3CCM D;  3CCU D;  3CD6 D;  3DLL D;  4U67 D;  1K9M F;  3G6E D;  3PIP D;  1JJ2 D;  1W2B D;  5GAE F;  1KD1 F;  3CCE D;  1Q82 F;  3CMA D;  4IOC D;  3I56 D;  3CC7 D;  3OW2 D;  2WNY A;  1YJ9 D;  1K73 F;  5MLC G;  1NJI F;  4IOA D;  1VQK D;  2ZJQ D;  5HL7 D;  1S72 D;  3G4S D;  1QVF D;  1MJI A;  1YI2 D;  3J7Z F;  4WFA D;  3I55 D; 
#chains in the Genus database with same CATH topology
 1YIT D;  3D7A A;  2OTJ D;  1VQ5 D;  2QA4 D;  5GAD F;  3CME D;  1VQM D;  1YJN D;  1KC8 F;  5JVH D;  1VQ8 D;  1Q81 F;  5DM6 D;  1KQS D;  3CXC D;  2ZJR D;  1IQ4 A;  3CCL D;  1M90 F;  1YHQ D;  3CCV D;  1VQ9 D;  1VQP D;  3C9G A;  1YIJ D;  3CCJ D;  5GAG F;  4WCE D;  3CCR D;  3CC2 D;  2OGK A;  3G71 D;  5GAH F;  3CCQ D;  1Q7Y F;  1Q86 F;  4WFB D;  4WFN D;  1VQ7 D;  1K8A F;  5H1S H;  1VQO D;  3CPW D;  2PZZ A;  1VQ6 D;  4UY8 F;  1VQL D;  3CCS D;  4WF9 D;  2NRQ A;  3PIO D;  4IO9 D;  1YJW D;  1QVG D;  1M1K F;  2QEX D;  1N8R F;  3CF5 D;  1VQ4 D;  2ZJP D;  5JVG D;  3CC4 D;  1VQN D;  2OTL D;  2NWU A;  5DM7 D;  3CCM D;  3CCU D;  3CD6 D;  3DLL D;  4U67 D;  1K9M F;  3G6E D;  3PIP D;  1JJ2 D;  1W2B D;  5GAE F;  1KD1 F;  3CCE D;  1Q82 F;  3CMA D;  4IOC D;  3I56 D;  3CC7 D;  3OW2 D;  2WNY A;  1YJ9 D;  1K73 F;  5MLC G;  1NJI F;  4IOA D;  1VQK D;  2ZJQ D;  5HL7 D;  1S72 D;  3G4S D;  1QVF D;  1MJI A;  1YI2 D;  3J7Z F;  4WFA D;  3I55 D; 
#chains in the Genus database with same CATH homology
 1YIT D;  3D7A A;  2OTJ D;  1VQ5 D;  2QA4 D;  5GAD F;  3CME D;  1VQM D;  1YJN D;  1KC8 F;  5JVH D;  1VQ8 D;  1Q81 F;  5DM6 D;  1KQS D;  3CXC D;  2ZJR D;  1IQ4 A;  3CCL D;  1M90 F;  1YHQ D;  3CCV D;  1VQ9 D;  1VQP D;  3C9G A;  1YIJ D;  3CCJ D;  5GAG F;  4WCE D;  3CCR D;  3CC2 D;  2OGK A;  3G71 D;  5GAH F;  3CCQ D;  1Q7Y F;  1Q86 F;  4WFB D;  4WFN D;  1VQ7 D;  1K8A F;  5H1S H;  1VQO D;  3CPW D;  2PZZ A;  1VQ6 D;  4UY8 F;  1VQL D;  3CCS D;  4WF9 D;  2NRQ A;  3PIO D;  4IO9 D;  1YJW D;  1QVG D;  1M1K F;  2QEX D;  1N8R F;  3CF5 D;  1VQ4 D;  2ZJP D;  5JVG D;  3CC4 D;  1VQN D;  2OTL D;  2NWU A;  5DM7 D;  3CCM D;  3CCU D;  3CD6 D;  3DLL D;  4U67 D;  1K9M F;  3G6E D;  3PIP D;  1JJ2 D;  1W2B D;  5GAE F;  1KD1 F;  3CCE D;  1Q82 F;  3CMA D;  4IOC D;  3I56 D;  3CC7 D;  3OW2 D;  2WNY A;  1YJ9 D;  1K73 F;  5MLC G;  1NJI F;  4IOA D;  1VQK D;  2ZJQ D;  5HL7 D;  1S72 D;  3G4S D;  1QVF D;  1MJI A;  1YI2 D;  3J7Z F;  4WFA D;  3I55 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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