3CCVD

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation g2616a
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 18
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3ccvD00
3CXCD 1VQ8D 4U67D 1VQOD 3CPWD 1NJIF 3CF5D 1VQPD 3CC2D 1K8AF 3OW2D 4IOCD 1K9MF 3CCVD 2OTJD 5JVGD 2OGKA 1M90F 1VQ6D 3J7ZF 2NWUA 1JJ2D 2NRQA 3G71D 5DM7D 1Q82F 1KQSD 1VQ5D 3CC4D 4WFND 1YI2D 5H1SH 3CCLD 1Q86F 1YIJD 3CCED 5GAGF 2QEXD 1QVFD 3CCSD 3CCRD 1KD1F 1VQLD 2PZZA 4WCED 4IO9D 1QVGD 1IQ4A 1VQ9D 1YJ9D 1MJIA 1VQMD 1VQND 1Q7YF 5HL7D 3CCJD 1Q81F 3D7AA 5DM6D 2ZJPD 1YJWD 3G6ED 2WNYA 3CC7D 1W2BD 3PIOD 2ZJQD 1N8RF 2OTLD 1KC8F 3CMAD 1YHQD 3CCMD 4WFAD 1S72D 2ZJRD 5GADF 3I56D 3DLLD 4UY8F 3PIPD 1YJND 4WFBD 4IOAD 5GAEF 3CMED 1K73F 5GAHF 1VQ4D 5MLCG 3C9GA 4WF9D 1VQ7D 1M1KF 3CCUD 2QA4D 1YITD 5JVHD 3CCQD 3I55D 3CD6D 3G4SD 1VQKD
chains in the Genus database with same CATH superfamily
3CXCD 1VQ8D 4U67D 1VQOD 3CPWD 1NJIF 3CF5D 1VQPD 3CC2D 1K8AF 3OW2D 4IOCD 1K9MF 3CCVD 2OTJD 5JVGD 2OGKA 1M90F 1VQ6D 3J7ZF 2NWUA 1JJ2D 2NRQA 3G71D 5DM7D 1Q82F 1KQSD 1VQ5D 3CC4D 4WFND 1YI2D 5H1SH 3CCLD 1Q86F 1YIJD 3CCED 5GAGF 2QEXD 1QVFD 3CCSD 3CCRD 1KD1F 1VQLD 2PZZA 4WCED 4IO9D 1QVGD 1IQ4A 1VQ9D 1YJ9D 1MJIA 1VQMD 1VQND 1Q7YF 5HL7D 3CCJD 1Q81F 3D7AA 5DM6D 2ZJPD 1YJWD 3G6ED 2WNYA 3CC7D 1W2BD 3PIOD 2ZJQD 1N8RF 2OTLD 1KC8F 3CMAD 1YHQD 3CCMD 4WFAD 1S72D 2ZJRD 5GADF 3I56D 3DLLD 4UY8F 3PIPD 1YJND 4WFBD 4IOAD 5GAEF 3CMED 1K73F 5GAHF 1VQ4D 5MLCG 3C9GA 4WF9D 1VQ7D 1M1KF 3CCUD 2QA4D 1YITD 5JVHD 3CCQD 3I55D 3CD6D 3G4SD 1VQKD
chains in the Genus database with same CATH topology
3CXCD 1VQ8D 4U67D 1VQOD 3CPWD 1NJIF 3CF5D 1VQPD 3CC2D 1K8AF 3OW2D 4IOCD 1K9MF 3CCVD 2OTJD 5JVGD 2OGKA 1M90F 1VQ6D 3J7ZF 2NWUA 1JJ2D 2NRQA 3G71D 5DM7D 1Q82F 1KQSD 1VQ5D 3CC4D 4WFND 1YI2D 5H1SH 3CCLD 1Q86F 1YIJD 3CCED 5GAGF 2QEXD 1QVFD 3CCSD 3CCRD 1KD1F 1VQLD 2PZZA 4WCED 4IO9D 1QVGD 1IQ4A 1VQ9D 1YJ9D 1MJIA 1VQMD 1VQND 1Q7YF 5HL7D 3CCJD 1Q81F 3D7AA 5DM6D 2ZJPD 1YJWD 3G6ED 2WNYA 3CC7D 1W2BD 3PIOD 2ZJQD 1N8RF 2OTLD 1KC8F 3CMAD 1YHQD 3CCMD 4WFAD 1S72D 2ZJRD 5GADF 3I56D 3DLLD 4UY8F 3PIPD 1YJND 4WFBD 4IOAD 5GAEF 3CMED 1K73F 5GAHF 1VQ4D 5MLCG 3C9GA 4WF9D 1VQ7D 1M1KF 3CCUD 2QA4D 1YITD 5JVHD 3CCQD 3I55D 3CD6D 3G4SD 1VQKD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CXC D;  1VQ8 D;  4U67 D;  1VQO D;  3CPW D;  1NJI F;  3CF5 D;  1VQP D;  3CC2 D;  1K8A F;  3OW2 D;  4IOC D;  1K9M F;  3CCV D;  2OTJ D;  5JVG D;  2OGK A;  1M90 F;  1VQ6 D;  3J7Z F;  2NWU A;  1JJ2 D;  2NRQ A;  3G71 D;  5DM7 D;  1Q82 F;  1KQS D;  1VQ5 D;  3CC4 D;  4WFN D;  1YI2 D;  5H1S H;  3CCL D;  1Q86 F;  1YIJ D;  3CCE D;  5GAG F;  2QEX D;  1QVF D;  3CCS D;  3CCR D;  1KD1 F;  1VQL D;  2PZZ A;  4WCE D;  4IO9 D;  1QVG D;  1IQ4 A;  1VQ9 D;  1YJ9 D;  1MJI A;  1VQM D;  1VQN D;  1Q7Y F;  5HL7 D;  3CCJ D;  1Q81 F;  3D7A A;  5DM6 D;  2ZJP D;  1YJW D;  3G6E D;  2WNY A;  3CC7 D;  1W2B D;  3PIO D;  2ZJQ D;  1N8R F;  2OTL D;  1KC8 F;  3CMA D;  1YHQ D;  3CCM D;  4WFA D;  1S72 D;  2ZJR D;  5GAD F;  3I56 D;  3DLL D;  4UY8 F;  3PIP D;  1YJN D;  4WFB D;  4IOA D;  5GAE F;  3CME D;  1K73 F;  5GAH F;  1VQ4 D;  5MLC G;  3C9G A;  4WF9 D;  1VQ7 D;  1M1K F;  3CCU D;  2QA4 D;  1YIT D;  5JVH D;  3CCQ D;  3I55 D;  3CD6 D;  3G4S D;  1VQK D; 
#chains in the Genus database with same CATH topology
 3CXC D;  1VQ8 D;  4U67 D;  1VQO D;  3CPW D;  1NJI F;  3CF5 D;  1VQP D;  3CC2 D;  1K8A F;  3OW2 D;  4IOC D;  1K9M F;  3CCV D;  2OTJ D;  5JVG D;  2OGK A;  1M90 F;  1VQ6 D;  3J7Z F;  2NWU A;  1JJ2 D;  2NRQ A;  3G71 D;  5DM7 D;  1Q82 F;  1KQS D;  1VQ5 D;  3CC4 D;  4WFN D;  1YI2 D;  5H1S H;  3CCL D;  1Q86 F;  1YIJ D;  3CCE D;  5GAG F;  2QEX D;  1QVF D;  3CCS D;  3CCR D;  1KD1 F;  1VQL D;  2PZZ A;  4WCE D;  4IO9 D;  1QVG D;  1IQ4 A;  1VQ9 D;  1YJ9 D;  1MJI A;  1VQM D;  1VQN D;  1Q7Y F;  5HL7 D;  3CCJ D;  1Q81 F;  3D7A A;  5DM6 D;  2ZJP D;  1YJW D;  3G6E D;  2WNY A;  3CC7 D;  1W2B D;  3PIO D;  2ZJQ D;  1N8R F;  2OTL D;  1KC8 F;  3CMA D;  1YHQ D;  3CCM D;  4WFA D;  1S72 D;  2ZJR D;  5GAD F;  3I56 D;  3DLL D;  4UY8 F;  3PIP D;  1YJN D;  4WFB D;  4IOA D;  5GAE F;  3CME D;  1K73 F;  5GAH F;  1VQ4 D;  5MLC G;  3C9G A;  4WF9 D;  1VQ7 D;  1M1K F;  3CCU D;  2QA4 D;  1YIT D;  5JVH D;  3CCQ D;  3I55 D;  3CD6 D;  3G4S D;  1VQK D; 
#chains in the Genus database with same CATH homology
 3CXC D;  1VQ8 D;  4U67 D;  1VQO D;  3CPW D;  1NJI F;  3CF5 D;  1VQP D;  3CC2 D;  1K8A F;  3OW2 D;  4IOC D;  1K9M F;  3CCV D;  2OTJ D;  5JVG D;  2OGK A;  1M90 F;  1VQ6 D;  3J7Z F;  2NWU A;  1JJ2 D;  2NRQ A;  3G71 D;  5DM7 D;  1Q82 F;  1KQS D;  1VQ5 D;  3CC4 D;  4WFN D;  1YI2 D;  5H1S H;  3CCL D;  1Q86 F;  1YIJ D;  3CCE D;  5GAG F;  2QEX D;  1QVF D;  3CCS D;  3CCR D;  1KD1 F;  1VQL D;  2PZZ A;  4WCE D;  4IO9 D;  1QVG D;  1IQ4 A;  1VQ9 D;  1YJ9 D;  1MJI A;  1VQM D;  1VQN D;  1Q7Y F;  5HL7 D;  3CCJ D;  1Q81 F;  3D7A A;  5DM6 D;  2ZJP D;  1YJW D;  3G6E D;  2WNY A;  3CC7 D;  1W2B D;  3PIO D;  2ZJQ D;  1N8R F;  2OTL D;  1KC8 F;  3CMA D;  1YHQ D;  3CCM D;  4WFA D;  1S72 D;  2ZJR D;  5GAD F;  3I56 D;  3DLL D;  4UY8 F;  3PIP D;  1YJN D;  4WFB D;  4IOA D;  5GAE F;  3CME D;  1K73 F;  5GAH F;  1VQ4 D;  5MLC G;  3C9G A;  4WF9 D;  1VQ7 D;  1M1K F;  3CCU D;  2QA4 D;  1YIT D;  5JVH D;  3CCQ D;  3I55 D;  3CD6 D;  3G4S D;  1VQK D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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