3CD6D

Co-cystal of large ribosomal subunit mutant g2616a with cc-puromycin
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
165
structure length
140
Chain Sequence
FHEMREPRIEKVVVHMGIGHANAEDILGEITGQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFLQTALPLAELATSQFDDTGNFSFGLDVTVNLVRPGYRVAKRDKASRSIPTKHRLNPADAVAFIESTYDVEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 14
structure length 140
sequence length 165
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 3cd6D00
2QEXD 1VQ7D 3CCED 4UY8F 3PIPD 3G6ED 1M90F 1VQPD 1YITD 4WFAD 1K8AF 5DM7D 1IQ4A 1QVFD 3G71D 1VQLD 1S72D 3CCRD 1VQOD 3CCQD 5GAGF 3G4SD 3I56D 4IOAD 3CC4D 1YI2D 1YJ9D 3CPWD 3OW2D 1KC8F 3I55D 1VQND 2ZJRD 3CC7D 1M1KF 5GAEF 3CXCD 1YIJD 2OGKA 2NRQA 3CD6D 4WFND 4IOCD 4IO9D 2PZZA 3CCVD 1YHQD 3J7ZF 4U67D 1VQ9D 3CF5D 2OTJD 1K9MF 1KD1F 1JJ2D 2ZJQD 2WNYA 3CCUD 1KQSD 1VQKD 3C9GA 5MLCG 3PIOD 5HL7D 5H1SH 1Q82F 1Q86F 3CCSD 2NWUA 3D7AA 5JVHD 4WFBD 1W2BD 3CCMD 1QVGD 1N8RF 1Q81F 5GAHF 1MJIA 2QA4D 4WF9D 4WCED 3DLLD 1NJIF 1Q7YF 2ZJPD 1YJWD 1VQ5D 5DM6D 5GADF 1VQMD 5JVGD 2OTLD 1K73F 3CC2D 3CCJD 1YJND 3CMAD 3CMED 1VQ6D 1VQ8D 1VQ4D 3CCLD
chains in the Genus database with same CATH superfamily
2QEXD 1VQ7D 3CCED 4UY8F 3PIPD 3G6ED 1M90F 1VQPD 1YITD 4WFAD 1K8AF 5DM7D 1IQ4A 1QVFD 3G71D 1VQLD 1S72D 3CCRD 1VQOD 3CCQD 5GAGF 3G4SD 3I56D 4IOAD 3CC4D 1YI2D 1YJ9D 3CPWD 3OW2D 1KC8F 3I55D 1VQND 2ZJRD 3CC7D 1M1KF 5GAEF 3CXCD 1YIJD 2OGKA 2NRQA 3CD6D 4WFND 4IOCD 4IO9D 2PZZA 3CCVD 1YHQD 3J7ZF 4U67D 1VQ9D 3CF5D 2OTJD 1K9MF 1KD1F 1JJ2D 2ZJQD 2WNYA 3CCUD 1KQSD 1VQKD 3C9GA 5MLCG 3PIOD 5HL7D 5H1SH 1Q82F 1Q86F 3CCSD 2NWUA 3D7AA 5JVHD 4WFBD 1W2BD 3CCMD 1QVGD 1N8RF 1Q81F 5GAHF 1MJIA 2QA4D 4WF9D 4WCED 3DLLD 1NJIF 1Q7YF 2ZJPD 1YJWD 1VQ5D 5DM6D 5GADF 1VQMD 5JVGD 2OTLD 1K73F 3CC2D 3CCJD 1YJND 3CMAD 3CMED 1VQ6D 1VQ8D 1VQ4D 3CCLD
chains in the Genus database with same CATH topology
2QEXD 1VQ7D 3CCED 4UY8F 3PIPD 3G6ED 1M90F 1VQPD 1YITD 4WFAD 1K8AF 5DM7D 1IQ4A 1QVFD 3G71D 1VQLD 1S72D 3CCRD 1VQOD 3CCQD 5GAGF 3G4SD 3I56D 4IOAD 3CC4D 1YI2D 1YJ9D 3CPWD 3OW2D 1KC8F 3I55D 1VQND 2ZJRD 3CC7D 1M1KF 5GAEF 3CXCD 1YIJD 2OGKA 2NRQA 3CD6D 4WFND 4IOCD 4IO9D 2PZZA 3CCVD 1YHQD 3J7ZF 4U67D 1VQ9D 3CF5D 2OTJD 1K9MF 1KD1F 1JJ2D 2ZJQD 2WNYA 3CCUD 1KQSD 1VQKD 3C9GA 5MLCG 3PIOD 5HL7D 5H1SH 1Q82F 1Q86F 3CCSD 2NWUA 3D7AA 5JVHD 4WFBD 1W2BD 3CCMD 1QVGD 1N8RF 1Q81F 5GAHF 1MJIA 2QA4D 4WF9D 4WCED 3DLLD 1NJIF 1Q7YF 2ZJPD 1YJWD 1VQ5D 5DM6D 5GADF 1VQMD 5JVGD 2OTLD 1K73F 3CC2D 3CCJD 1YJND 3CMAD 3CMED 1VQ6D 1VQ8D 1VQ4D 3CCLD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QEX D;  1VQ7 D;  3CCE D;  4UY8 F;  3PIP D;  3G6E D;  1M90 F;  1VQP D;  1YIT D;  4WFA D;  1K8A F;  5DM7 D;  1IQ4 A;  1QVF D;  3G71 D;  1VQL D;  1S72 D;  3CCR D;  1VQO D;  3CCQ D;  5GAG F;  3G4S D;  3I56 D;  4IOA D;  3CC4 D;  1YI2 D;  1YJ9 D;  3CPW D;  3OW2 D;  1KC8 F;  3I55 D;  1VQN D;  2ZJR D;  3CC7 D;  1M1K F;  5GAE F;  3CXC D;  1YIJ D;  2OGK A;  2NRQ A;  3CD6 D;  4WFN D;  4IOC D;  4IO9 D;  2PZZ A;  3CCV D;  1YHQ D;  3J7Z F;  4U67 D;  1VQ9 D;  3CF5 D;  2OTJ D;  1K9M F;  1KD1 F;  1JJ2 D;  2ZJQ D;  2WNY A;  3CCU D;  1KQS D;  1VQK D;  3C9G A;  5MLC G;  3PIO D;  5HL7 D;  5H1S H;  1Q82 F;  1Q86 F;  3CCS D;  2NWU A;  3D7A A;  5JVH D;  4WFB D;  1W2B D;  3CCM D;  1QVG D;  1N8R F;  1Q81 F;  5GAH F;  1MJI A;  2QA4 D;  4WF9 D;  4WCE D;  3DLL D;  1NJI F;  1Q7Y F;  2ZJP D;  1YJW D;  1VQ5 D;  5DM6 D;  5GAD F;  1VQM D;  5JVG D;  2OTL D;  1K73 F;  3CC2 D;  3CCJ D;  1YJN D;  3CMA D;  3CME D;  1VQ6 D;  1VQ8 D;  1VQ4 D;  3CCL D; 
#chains in the Genus database with same CATH topology
 2QEX D;  1VQ7 D;  3CCE D;  4UY8 F;  3PIP D;  3G6E D;  1M90 F;  1VQP D;  1YIT D;  4WFA D;  1K8A F;  5DM7 D;  1IQ4 A;  1QVF D;  3G71 D;  1VQL D;  1S72 D;  3CCR D;  1VQO D;  3CCQ D;  5GAG F;  3G4S D;  3I56 D;  4IOA D;  3CC4 D;  1YI2 D;  1YJ9 D;  3CPW D;  3OW2 D;  1KC8 F;  3I55 D;  1VQN D;  2ZJR D;  3CC7 D;  1M1K F;  5GAE F;  3CXC D;  1YIJ D;  2OGK A;  2NRQ A;  3CD6 D;  4WFN D;  4IOC D;  4IO9 D;  2PZZ A;  3CCV D;  1YHQ D;  3J7Z F;  4U67 D;  1VQ9 D;  3CF5 D;  2OTJ D;  1K9M F;  1KD1 F;  1JJ2 D;  2ZJQ D;  2WNY A;  3CCU D;  1KQS D;  1VQK D;  3C9G A;  5MLC G;  3PIO D;  5HL7 D;  5H1S H;  1Q82 F;  1Q86 F;  3CCS D;  2NWU A;  3D7A A;  5JVH D;  4WFB D;  1W2B D;  3CCM D;  1QVG D;  1N8R F;  1Q81 F;  5GAH F;  1MJI A;  2QA4 D;  4WF9 D;  4WCE D;  3DLL D;  1NJI F;  1Q7Y F;  2ZJP D;  1YJW D;  1VQ5 D;  5DM6 D;  5GAD F;  1VQM D;  5JVG D;  2OTL D;  1K73 F;  3CC2 D;  3CCJ D;  1YJN D;  3CMA D;  3CME D;  1VQ6 D;  1VQ8 D;  1VQ4 D;  3CCL D; 
#chains in the Genus database with same CATH homology
 2QEX D;  1VQ7 D;  3CCE D;  4UY8 F;  3PIP D;  3G6E D;  1M90 F;  1VQP D;  1YIT D;  4WFA D;  1K8A F;  5DM7 D;  1IQ4 A;  1QVF D;  3G71 D;  1VQL D;  1S72 D;  3CCR D;  1VQO D;  3CCQ D;  5GAG F;  3G4S D;  3I56 D;  4IOA D;  3CC4 D;  1YI2 D;  1YJ9 D;  3CPW D;  3OW2 D;  1KC8 F;  3I55 D;  1VQN D;  2ZJR D;  3CC7 D;  1M1K F;  5GAE F;  3CXC D;  1YIJ D;  2OGK A;  2NRQ A;  3CD6 D;  4WFN D;  4IOC D;  4IO9 D;  2PZZ A;  3CCV D;  1YHQ D;  3J7Z F;  4U67 D;  1VQ9 D;  3CF5 D;  2OTJ D;  1K9M F;  1KD1 F;  1JJ2 D;  2ZJQ D;  2WNY A;  3CCU D;  1KQS D;  1VQK D;  3C9G A;  5MLC G;  3PIO D;  5HL7 D;  5H1S H;  1Q82 F;  1Q86 F;  3CCS D;  2NWU A;  3D7A A;  5JVH D;  4WFB D;  1W2B D;  3CCM D;  1QVG D;  1N8R F;  1Q81 F;  5GAH F;  1MJI A;  2QA4 D;  4WF9 D;  4WCE D;  3DLL D;  1NJI F;  1Q7Y F;  2ZJP D;  1YJW D;  1VQ5 D;  5DM6 D;  5GAD F;  1VQM D;  5JVG D;  2OTL D;  1K73 F;  3CC2 D;  3CCJ D;  1YJN D;  3CMA D;  3CME D;  1VQ6 D;  1VQ8 D;  1VQ4 D;  3CCL D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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