3X27A

Structure of mcbb in complex with tryptophan
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
309
structure length
309
Chain Sequence
QIEIEWVQPGITVTADLSWERNPELAELLWTGLLPYNSLQNHALVSGNHLYHLIADPRLVYTEARYKEDRTKSPDGTVFLSQLQHLAVKYGPLTEYLPAAPVGSVVPEDIDALREAGRACWKAAWETKQPIEVRVRRKGEAVTDFALPRTPPVDHPGVQKLVEEIQDETERVWITPPAEIVDMHQGRIASRAGSYDQYFSTLVFLNGEVRPLGYCALNGLLKICRTTDLTLNDLKRITPTFIKTPAEFLGYTGLDTLWRFTQQVLTLLPDVETREQYFALVNALALYANMLNTWNLHFFPWQHGTDYRY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for beta-Carboline Alkaloid Production by the Microbial Homodimeric Enzyme McbB
pubmed doi rcsb
molecule tags Lyase
source organism Marinactinospora thermotolerans
molecule keywords Cucumopine synthase
total genus 105
structure length 309
sequence length 309
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18631 Cucumopine_C Cucumopine synthase C-terminal helical bundle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.100.20 Mainly Beta Beta Barrel Cyclophilin Cyclophilin 3x27A01
2NNZA 1ZX8A 3KOPA 3X27A 2KA0A
chains in the Genus database with same CATH superfamily
1MZWA 3JB9d 3RDBA 3UCHA 3MMLA 1M9FA 3VA7A 5KURA 3QYUA 5KUQA 1CWBA 4HY7A 1X7FA 2WLWA 1Z81A 3T1UA 5KULA 3R54A 4J5DX 2ZP2A 4N1QA 4YUHA 1RMHA 1MF8C 2RMCA 5KUOA 1BCKA 5KUUA 1MIKA 2X2DB 1M9XA 1CWHA 2HAQA 2CFEA 1IHGA 1AK4A 1AWVA 2NULA 3OPFA 3R59A 4J5AX 4S1JA 4TOTA 4YUNA 1FGLA 1W8LA 4DGAA 3KOPA 5KV5A 4JJMA 1M9CA 2X83B 3RCKX 1DYWA 1VBSA 3OEPA 4ZSCA 5KV6A 5CCQA 1XWNA 5KV1A 1E8KA 4FRUA 1CWCA 4S1EA 4YUKA 1CWAA 2XGYB 2Z6WA 1QNGA 3EOVA 3R57A 3K0QA 2IGWA 2QERA 4N1OA 5KV7A 3BO7A 1AWQA 2MZUA 2RS4A 1CWKA 5KUWA 1H0PA 2MS4A 5KUZA 4R3FA 1W74A 3RCLA 3S6MA 2POEA 4I9YA 2BITX 3RDCA 3RD9X 4J5CX 5CBVA 1VAIA 4DGDA 4N1MA 3ODIA 2KA0A 1XO7A 5KV3A 2OK3A 3ICHA 2X2CK 3RCFA 3RCIX 5CYHA 1A33A 1AWRA 3K0OA 1CWLA 2X2AA 1QOIA 1ZMFA 3RDAX 5JHEA 1CLHA 3CYHA 3R56A 1XQ7A 2BIUX 4LQWA 5DUDA 5KUNA 2B71A 1CWOA 4YUMA 1AWTA 4YUPA 2NNZA 1CWFA 2K7NA 4E1QA 4CYHA 3CYSA 4J58A 2CMTA 4YUOA 5KV2A 5CBUA 5A0EA 2PLUA 2WFIA 3PMPA 1V9TA 2POYA 1IIPA 4YUGA 4J5BA 1ZX8A 2CYHA 4DGBA 3K0MA 3BT8A 2C3BA 1CWJA 1QNHA 2RMBA 1CWIA 3K0PA 4N1SA 5KUSA 2MC9A 4FRVA 1J2AA 2R99A 4O8IA 3O7TA 3RFYA 3X27A 3OREA 1NMKA 1VBTA 4N1RA 4J5EX 4N1PA 1AWSA 1CYNA 2GW2A 3K2CA 4O8HA 4JCPA 4XNCA 1OCAA 1ZKFA 5CCSX 5KV4A 2A2NA 5KUVA 1M63C 4J59A 1XYHA 4DGCA 1ZKCA 2CPLA 5KV0A 1ISTA 3BKPA 4EYVA 3K0NA 3R49A 2PHCB 4IPZA 3R4GA 3RDDA 4YUJA 2ALFA 2OSEA 2N0TA 2P0OA 2X7KA 4YUIA 4R3EA 1CWMA 3ICIA 1LOPA 1A58A 2X25B 2HQ6A 2CK1A 1AWUA 1W8MA 2FU0A 1M9EA 2RMAA 3K0RA 4DGEA 1M9DA 5LUDA 2OJUA 1VDNA 2HQJA 4ZSDA 5CBWA 5F66A 1M9YA 5CCRA 5CBTA 1E3BA 2MVZA 1C5FA 4N1NA 4YULA 1YNDA 2HE9A 2ESLA 3RCGA 2WFJA 1W8VA 3MMLB 2IGVA 5CCNA 3ODLA
chains in the Genus database with same CATH topology
2NNZA 1ZX8A 3KOPA 3X27A 2KA0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NNZ A;  1ZX8 A;  3KOP A;  3X27 A;  2KA0 A; 
#chains in the Genus database with same CATH topology
 1MZW A;  3JB9 d;  3RDB A;  3UCH A;  3MML A;  1M9F A;  3VA7 A;  5KUR A;  3QYU A;  5KUQ A;  1CWB A;  4HY7 A;  1X7F A;  2WLW A;  1Z81 A;  3T1U A;  5KUL A;  3R54 A;  4J5D X;  2ZP2 A;  4N1Q A;  4YUH A;  1RMH A;  1MF8 C;  2RMC A;  5KUO A;  1BCK A;  5KUU A;  1MIK A;  2X2D B;  1M9X A;  1CWH A;  2HAQ A;  2CFE A;  1IHG A;  1AK4 A;  1AWV A;  2NUL A;  3OPF A;  3R59 A;  4J5A X;  4S1J A;  4TOT A;  4YUN A;  1FGL A;  1W8L A;  4DGA A;  3KOP A;  5KV5 A;  4JJM A;  1M9C A;  2X83 B;  3RCK X;  1DYW A;  1VBS A;  3OEP A;  4ZSC A;  5KV6 A;  5CCQ A;  1XWN A;  5KV1 A;  1E8K A;  4FRU A;  1CWC A;  4S1E A;  4YUK A;  1CWA A;  2XGY B;  2Z6W A;  1QNG A;  3EOV A;  3R57 A;  3K0Q A;  2IGW A;  2QER A;  4N1O A;  5KV7 A;  3BO7 A;  1AWQ A;  2MZU A;  2RS4 A;  1CWK A;  5KUW A;  1H0P A;  2MS4 A;  5KUZ A;  4R3F A;  1W74 A;  3RCL A;  3S6M A;  2POE A;  4I9Y A;  2BIT X;  3RDC A;  3RD9 X;  4J5C X;  5CBV A;  1VAI A;  4DGD A;  4N1M A;  3ODI A;  2KA0 A;  1XO7 A;  5KV3 A;  2OK3 A;  3ICH A;  2X2C K;  3RCF A;  3RCI X;  5CYH A;  1A33 A;  1AWR A;  3K0O A;  1CWL A;  2X2A A;  1QOI A;  1ZMF A;  3RDA X;  5JHE A;  1CLH A;  3CYH A;  3R56 A;  1XQ7 A;  2BIU X;  4LQW A;  5DUD A;  5KUN A;  2B71 A;  1CWO A;  4YUM A;  1AWT A;  4YUP A;  2NNZ A;  1CWF A;  2K7N A;  4E1Q A;  4CYH A;  3CYS A;  4J58 A;  2CMT A;  4YUO A;  5KV2 A;  5CBU A;  5A0E A;  2PLU A;  2WFI A;  3PMP A;  1V9T A;  2POY A;  1IIP A;  4YUG A;  4J5B A;  1ZX8 A;  2CYH A;  4DGB A;  3K0M A;  3BT8 A;  2C3B A;  1CWJ A;  1QNH A;  2RMB A;  1CWI A;  3K0P A;  4N1S A;  5KUS A;  2MC9 A;  4FRV A;  1J2A A;  2R99 A;  4O8I A;  3O7T A;  3RFY A;  3X27 A;  3ORE A;  1NMK A;  1VBT A;  4N1R A;  4J5E X;  4N1P A;  1AWS A;  1CYN A;  2GW2 A;  3K2C A;  4O8H A;  4JCP A;  4XNC A;  1OCA A;  1ZKF A;  5CCS X;  5KV4 A;  2A2N A;  5KUV A;  1M63 C;  4J59 A;  1XYH A;  4DGC A;  1ZKC A;  2CPL A;  5KV0 A;  1IST A;  3BKP A;  4EYV A;  3K0N A;  3R49 A;  2PHC B;  4IPZ A;  3R4G A;  3RDD A;  4YUJ A;  2ALF A;  2OSE A;  2N0T A;  2P0O A;  2X7K A;  4YUI A;  4R3E A;  1CWM A;  3ICI A;  1LOP A;  1A58 A;  2X25 B;  2HQ6 A;  2CK1 A;  1AWU A;  1W8M A;  2FU0 A;  1M9E A;  2RMA A;  3K0R A;  4DGE A;  1M9D A;  5LUD A;  2OJU A;  1VDN A;  2HQJ A;  4ZSD A;  5CBW A;  5F66 A;  1M9Y A;  5CCR A;  5CBT A;  1E3B A;  2MVZ A;  1C5F A;  4N1N A;  4YUL A;  1YND A;  2HE9 A;  2ESL A;  3RCG A;  2WFJ A;  1W8V A;  3MML B;  2IGV A;  5CCN A;  3ODL A; 
#chains in the Genus database with same CATH homology
 2NNZ A;  1ZX8 A;  3KOP A;  3X27 A;  2KA0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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