4BPWA

Crystal structure of human primase bound to utp
Total Genus 120
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
407
structure length
382
Chain Sequence
FDPTELPELLKLYYRRLFPYSQYYRWLNYGGVIKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQAANPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESWDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNPWLEWEIMLQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAIRTRDYKKTSLAPYVKVFEHFLENLDKSRKGEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Homo sapiens
publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
molecule keywords DNA PRIMASE SMALL SUBUNIT
total genus 120
structure length 382
sequence length 407
chains with identical sequence C
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01896 DNA_primase_S DNA primase small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.920.30 Alpha Beta Alpha-Beta Complex DNA primase, PRIM domain DNA primase, PRIM domain 4bpwA00
4BPWA 2FAOA 5EXRA 1ZT2A 4BPXA 4RR2A 2FARA 4MHQA 4LIMA 4LILA 4BPUA 4LIKA 2FAQA 4MM2A
chains in the Genus database with same CATH superfamily
4BPWA 2FAOA 5EXRA 1V33A 1ZT2A 4BPXA 4RR2A 2FARA 1V34A 4MHQA 4LIMA 4LILA 4BPUA 4LIKA 2FAQA 2ATZA 4MM2A 1G71A
chains in the Genus database with same CATH topology
4BPWA 2FAOA 5EXRA 1V33A 1ZT2A 4BPXA 4RR2A 2FARA 1V34A 4MHQA 4LIMA 4LILA 4BPUA 4LIKA 2FAQA 4MM2A 1G71A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BPW A;  2FAO A;  5EXR A;  1ZT2 A;  4BPX A;  4RR2 A;  2FAR A;  4MHQ A;  4LIM A;  4LIL A;  4BPU A;  4LIK A;  2FAQ A;  4MM2 A; 
#chains in the Genus database with same CATH topology
 4BPW A;  2FAO A;  5EXR A;  1V33 A;  1ZT2 A;  4BPX A;  4RR2 A;  2FAR A;  1V34 A;  4MHQ A;  4LIM A;  4LIL A;  4BPU A;  4LIK A;  2FAQ A;  2ATZ A;  4MM2 A;  1G71 A; 
#chains in the Genus database with same CATH homology
 4BPW A;  2FAO A;  5EXR A;  1V33 A;  1ZT2 A;  4BPX A;  4RR2 A;  2FAR A;  1V34 A;  4MHQ A;  4LIM A;  4LIL A;  4BPU A;  4LIK A;  2FAQ A;  4MM2 A;  1G71 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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