4ESQA

Crystal structure of the extracellular domain of pknh from mycobacterium tuberculosis
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
194
structure length
194
Chain Sequence
GHQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVDVNACGYQITNQAGQIAAKIVDKVNKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the sensor domain of Mycobacterium tuberculosis PknH receptor kinase reveals a conserved binding cleft.
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords Serine/threonine protein kinase
total genus 52
structure length 194
sequence length 194
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2012-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14032 PknH_C PknH-like extracellular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1000.70 Alpha Beta 3-Layer(aba) Sandwich Protein Transport Mog1p; Chain A Protein Transport Mog1p; Chain A 4esqA00
4ESQA
chains in the Genus database with same CATH superfamily
3HLZA 1VR8A 4BQ6D 4BQ8C 3JCUP 4N88B 4RTHA 4L9CA 3BCYA 4L9HA 4LUQC 3WA5B 4ESQA 4UI2D 3NR5A 2LNJA 2VU4A 1V2BA 1TU1A 3V7BA 1JHSA 4RTIA 4N7SB 3LYDA 2XB3A 4OUHA 4N80B 4M5FB 1EQ6A 2VT8A
chains in the Genus database with same CATH topology
4LUQC 4N88B 3WA5B 4ESQA 4N7SB 4L9CA 4OUHA 4N80B 4M5FB 4L9HA 2VT8A 3NR5A 3BCYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ESQ A; 
#chains in the Genus database with same CATH topology
 3HLZ A;  1VR8 A;  4BQ6 D;  4BQ8 C;  3JCU P;  4N88 B;  4RTH A;  4L9C A;  3BCY A;  4L9H A;  4LUQ C;  3WA5 B;  4ESQ A;  4UI2 D;  3NR5 A;  2LNJ A;  2VU4 A;  1V2B A;  1TU1 A;  3V7B A;  1JHS A;  4RTI A;  4N7S B;  3LYD A;  2XB3 A;  4OUH A;  4N80 B;  4M5F B;  1EQ6 A;  2VT8 A; 
#chains in the Genus database with same CATH homology
 4LUQ C;  4N88 B;  3WA5 B;  4ESQ A;  4N7S B;  4L9C A;  4OUH A;  4N80 B;  4M5F B;  4L9H A;  2VT8 A;  3NR5 A;  3BCY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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