4IOAD

Crystal structure of compound 4e bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
177
structure length
177
Chain Sequence
QLKTKYNDQVRPALMQQFGYSSVMAVPRIEKIVVNEGLGSSKEDSKAIDKAAKELALITLQKPIITKAKKSISNFKLRQGMPVGIKVTLRGERMYVFLEKLINIGLPRIRDFRGINPNAFDGRGNYNLGIKEQLIFPEITYDMVDKTRGMDITIVTTAKTDEEARALLQSMGLPFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 24
structure length 177
sequence length 177
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 4ioaD00
3G6ED 3CD6D 2OGKA 3CCJD 1KC8F 1Q82F 4WCED 1YHQD 1VQ6D 4IOCD 1S72D 1VQOD 1VQ4D 4IO9D 2ZJQD 2WNYA 1YJ9D 5GAHF 3J7ZF 3PIPD 3CF5D 2NRQA 3CCVD 2OTJD 3C9GA 5MLCG 3CCSD 3CC4D 1Q81F 5DM7D 3CC2D 3CMAD 1VQ7D 1QVGD 1IQ4A 3G71D 1VQKD 2PZZA 1VQLD 1YJWD 3I56D 3I55D 1KQSD 3CCQD 1M1KF 3CXCD 3CC7D 1VQND 5GADF 5JVGD 1JJ2D 3CCRD 3PIOD 4WFAD 5GAEF 1K8AF 3CCLD 3G4SD 1KD1F 1Q86F 4WF9D 2ZJRD 1VQMD 1YITD 3CMED 1W2BD 1M90F 3DLLD 1VQ9D 4U67D 3D7AA 4WFND 1VQ5D 4WFBD 2QA4D 5H1SH 5DM6D 3CPWD 1VQPD 1YI2D 3CCED 1YIJD 1Q7YF 5HL7D 3CCUD 2NWUA 1QVFD 1MJIA 4UY8F 4IOAD 5JVHD 1NJIF 1YJND 1N8RF 5GAGF 1VQ8D 3OW2D 2OTLD 2ZJPD 2QEXD 1K9MF 1K73F 3CCMD
chains in the Genus database with same CATH superfamily
3G6ED 3CD6D 2OGKA 3CCJD 1KC8F 1Q82F 4WCED 1YHQD 1VQ6D 4IOCD 1S72D 1VQOD 1VQ4D 4IO9D 2ZJQD 2WNYA 1YJ9D 5GAHF 3J7ZF 3PIPD 3CF5D 2NRQA 3CCVD 2OTJD 3C9GA 5MLCG 3CCSD 3CC4D 1Q81F 5DM7D 3CC2D 3CMAD 1VQ7D 1QVGD 1IQ4A 3G71D 1VQKD 2PZZA 1VQLD 1YJWD 3I56D 3I55D 1KQSD 3CCQD 1M1KF 3CXCD 3CC7D 1VQND 5GADF 5JVGD 1JJ2D 3CCRD 3PIOD 4WFAD 5GAEF 1K8AF 3CCLD 3G4SD 1KD1F 1Q86F 4WF9D 2ZJRD 1VQMD 1YITD 3CMED 1W2BD 1M90F 3DLLD 1VQ9D 4U67D 3D7AA 4WFND 1VQ5D 4WFBD 2QA4D 5H1SH 5DM6D 3CPWD 1VQPD 1YI2D 3CCED 1YIJD 1Q7YF 5HL7D 3CCUD 2NWUA 1QVFD 1MJIA 4UY8F 4IOAD 5JVHD 1NJIF 1YJND 1N8RF 5GAGF 1VQ8D 3OW2D 2OTLD 2ZJPD 2QEXD 1K9MF 1K73F 3CCMD
chains in the Genus database with same CATH topology
3G6ED 3CD6D 2OGKA 3CCJD 1KC8F 1Q82F 4WCED 1YHQD 1VQ6D 4IOCD 1S72D 1VQOD 1VQ4D 4IO9D 2ZJQD 2WNYA 1YJ9D 5GAHF 3J7ZF 3PIPD 3CF5D 2NRQA 3CCVD 2OTJD 3C9GA 5MLCG 3CCSD 3CC4D 1Q81F 5DM7D 3CC2D 3CMAD 1VQ7D 1QVGD 1IQ4A 3G71D 1VQKD 2PZZA 1VQLD 1YJWD 3I56D 3I55D 1KQSD 3CCQD 1M1KF 3CXCD 3CC7D 1VQND 5GADF 5JVGD 1JJ2D 3CCRD 3PIOD 4WFAD 5GAEF 1K8AF 3CCLD 3G4SD 1KD1F 1Q86F 4WF9D 2ZJRD 1VQMD 1YITD 3CMED 1W2BD 1M90F 3DLLD 1VQ9D 4U67D 3D7AA 4WFND 1VQ5D 4WFBD 2QA4D 5H1SH 5DM6D 3CPWD 1VQPD 1YI2D 3CCED 1YIJD 1Q7YF 5HL7D 3CCUD 2NWUA 1QVFD 1MJIA 4UY8F 4IOAD 5JVHD 1NJIF 1YJND 1N8RF 5GAGF 1VQ8D 3OW2D 2OTLD 2ZJPD 2QEXD 1K9MF 1K73F 3CCMD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G6E D;  3CD6 D;  2OGK A;  3CCJ D;  1KC8 F;  1Q82 F;  4WCE D;  1YHQ D;  1VQ6 D;  4IOC D;  1S72 D;  1VQO D;  1VQ4 D;  4IO9 D;  2ZJQ D;  2WNY A;  1YJ9 D;  5GAH F;  3J7Z F;  3PIP D;  3CF5 D;  2NRQ A;  3CCV D;  2OTJ D;  3C9G A;  5MLC G;  3CCS D;  3CC4 D;  1Q81 F;  5DM7 D;  3CC2 D;  3CMA D;  1VQ7 D;  1QVG D;  1IQ4 A;  3G71 D;  1VQK D;  2PZZ A;  1VQL D;  1YJW D;  3I56 D;  3I55 D;  1KQS D;  3CCQ D;  1M1K F;  3CXC D;  3CC7 D;  1VQN D;  5GAD F;  5JVG D;  1JJ2 D;  3CCR D;  3PIO D;  4WFA D;  5GAE F;  1K8A F;  3CCL D;  3G4S D;  1KD1 F;  1Q86 F;  4WF9 D;  2ZJR D;  1VQM D;  1YIT D;  3CME D;  1W2B D;  1M90 F;  3DLL D;  1VQ9 D;  4U67 D;  3D7A A;  4WFN D;  1VQ5 D;  4WFB D;  2QA4 D;  5H1S H;  5DM6 D;  3CPW D;  1VQP D;  1YI2 D;  3CCE D;  1YIJ D;  1Q7Y F;  5HL7 D;  3CCU D;  2NWU A;  1QVF D;  1MJI A;  4UY8 F;  4IOA D;  5JVH D;  1NJI F;  1YJN D;  1N8R F;  5GAG F;  1VQ8 D;  3OW2 D;  2OTL D;  2ZJP D;  2QEX D;  1K9M F;  1K73 F;  3CCM D; 
#chains in the Genus database with same CATH topology
 3G6E D;  3CD6 D;  2OGK A;  3CCJ D;  1KC8 F;  1Q82 F;  4WCE D;  1YHQ D;  1VQ6 D;  4IOC D;  1S72 D;  1VQO D;  1VQ4 D;  4IO9 D;  2ZJQ D;  2WNY A;  1YJ9 D;  5GAH F;  3J7Z F;  3PIP D;  3CF5 D;  2NRQ A;  3CCV D;  2OTJ D;  3C9G A;  5MLC G;  3CCS D;  3CC4 D;  1Q81 F;  5DM7 D;  3CC2 D;  3CMA D;  1VQ7 D;  1QVG D;  1IQ4 A;  3G71 D;  1VQK D;  2PZZ A;  1VQL D;  1YJW D;  3I56 D;  3I55 D;  1KQS D;  3CCQ D;  1M1K F;  3CXC D;  3CC7 D;  1VQN D;  5GAD F;  5JVG D;  1JJ2 D;  3CCR D;  3PIO D;  4WFA D;  5GAE F;  1K8A F;  3CCL D;  3G4S D;  1KD1 F;  1Q86 F;  4WF9 D;  2ZJR D;  1VQM D;  1YIT D;  3CME D;  1W2B D;  1M90 F;  3DLL D;  1VQ9 D;  4U67 D;  3D7A A;  4WFN D;  1VQ5 D;  4WFB D;  2QA4 D;  5H1S H;  5DM6 D;  3CPW D;  1VQP D;  1YI2 D;  3CCE D;  1YIJ D;  1Q7Y F;  5HL7 D;  3CCU D;  2NWU A;  1QVF D;  1MJI A;  4UY8 F;  4IOA D;  5JVH D;  1NJI F;  1YJN D;  1N8R F;  5GAG F;  1VQ8 D;  3OW2 D;  2OTL D;  2ZJP D;  2QEX D;  1K9M F;  1K73 F;  3CCM D; 
#chains in the Genus database with same CATH homology
 3G6E D;  3CD6 D;  2OGK A;  3CCJ D;  1KC8 F;  1Q82 F;  4WCE D;  1YHQ D;  1VQ6 D;  4IOC D;  1S72 D;  1VQO D;  1VQ4 D;  4IO9 D;  2ZJQ D;  2WNY A;  1YJ9 D;  5GAH F;  3J7Z F;  3PIP D;  3CF5 D;  2NRQ A;  3CCV D;  2OTJ D;  3C9G A;  5MLC G;  3CCS D;  3CC4 D;  1Q81 F;  5DM7 D;  3CC2 D;  3CMA D;  1VQ7 D;  1QVG D;  1IQ4 A;  3G71 D;  1VQK D;  2PZZ A;  1VQL D;  1YJW D;  3I56 D;  3I55 D;  1KQS D;  3CCQ D;  1M1K F;  3CXC D;  3CC7 D;  1VQN D;  5GAD F;  5JVG D;  1JJ2 D;  3CCR D;  3PIO D;  4WFA D;  5GAE F;  1K8A F;  3CCL D;  3G4S D;  1KD1 F;  1Q86 F;  4WF9 D;  2ZJR D;  1VQM D;  1YIT D;  3CME D;  1W2B D;  1M90 F;  3DLL D;  1VQ9 D;  4U67 D;  3D7A A;  4WFN D;  1VQ5 D;  4WFB D;  2QA4 D;  5H1S H;  5DM6 D;  3CPW D;  1VQP D;  1YI2 D;  3CCE D;  1YIJ D;  1Q7Y F;  5HL7 D;  3CCU D;  2NWU A;  1QVF D;  1MJI A;  4UY8 F;  4IOA D;  5JVH D;  1NJI F;  1YJN D;  1N8R F;  5GAG F;  1VQ8 D;  3OW2 D;  2OTL D;  2ZJP D;  2QEX D;  1K9M F;  1K73 F;  3CCM D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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