4IOCD

Crystal structure of compound 4f bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
177
structure length
177
Chain Sequence
QLKTKYNDQVRPALMQQFGYSSVMAVPRIEKIVVNEGLGSSKEDSKAIDKAAKELALITLQKPIITKAKKSISNFKLRQGMPVGIKVTLRGERMYVFLEKLINIGLPRIRDFRGINPNAFDGRGNYNLGIKEQLIFPEITYDMVDKTRGMDITIVTTAKTDEEARALLQSMGLPFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 25
structure length 177
sequence length 177
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 4iocD00
2QEXD 1VQPD 3PIPD 1QVGD 1N8RF 1VQ6D 4WFAD 5H1SH 4WCED 1K8AF 4WFND 1YJWD 1VQ5D 1M1KF 2ZJQD 5DM7D 1S72D 5MLCG 1VQ9D 2PZZA 3G4SD 2OTJD 1VQMD 3J7ZF 3CCSD 3DLLD 2QA4D 3CCLD 1W2BD 1QVFD 2ZJRD 1YITD 3CCQD 3I55D 3CCED 5GAGF 4IOCD 1NJIF 3CD6D 3CMED 4U67D 1YI2D 3I56D 1YJND 4WF9D 3CCUD 1VQND 3PIOD 4IO9D 2WNYA 3CMAD 1VQ7D 1YIJD 1JJ2D 3CC2D 1K9MF 3G6ED 1M90F 5GAHF 4IOAD 4UY8F 3CC4D 1YHQD 3G71D 1IQ4A 3CCVD 5GADF 3OW2D 1YJ9D 1KD1F 1VQLD 1Q81F 1VQKD 3CCRD 2NRQA 3CPWD 3CC7D 5DM6D 1VQOD 1MJIA 1Q86F 3CXCD 3CCMD 5GAEF 1Q7YF 2ZJPD 1Q82F 1KC8F 2NWUA 2OTLD 1K73F 1VQ4D 5JVGD 3CCJD 3C9GA 5JVHD 5HL7D 4WFBD 3CF5D 3D7AA 1KQSD 2OGKA 1VQ8D
chains in the Genus database with same CATH superfamily
2QEXD 1VQPD 3PIPD 1QVGD 1N8RF 1VQ6D 4WFAD 5H1SH 4WCED 1K8AF 4WFND 1YJWD 1VQ5D 1M1KF 2ZJQD 5DM7D 1S72D 5MLCG 1VQ9D 2PZZA 3G4SD 2OTJD 1VQMD 3J7ZF 3CCSD 3DLLD 2QA4D 3CCLD 1W2BD 1QVFD 2ZJRD 1YITD 3CCQD 3I55D 3CCED 5GAGF 4IOCD 1NJIF 3CD6D 3CMED 4U67D 1YI2D 3I56D 1YJND 4WF9D 3CCUD 1VQND 3PIOD 4IO9D 2WNYA 3CMAD 1VQ7D 1YIJD 1JJ2D 3CC2D 1K9MF 3G6ED 1M90F 5GAHF 4IOAD 4UY8F 3CC4D 1YHQD 3G71D 1IQ4A 3CCVD 5GADF 3OW2D 1YJ9D 1KD1F 1VQLD 1Q81F 1VQKD 3CCRD 2NRQA 3CPWD 3CC7D 5DM6D 1VQOD 1MJIA 1Q86F 3CXCD 3CCMD 5GAEF 1Q7YF 2ZJPD 1Q82F 1KC8F 2NWUA 2OTLD 1K73F 1VQ4D 5JVGD 3CCJD 3C9GA 5JVHD 5HL7D 4WFBD 3CF5D 3D7AA 1KQSD 2OGKA 1VQ8D
chains in the Genus database with same CATH topology
2QEXD 1VQPD 3PIPD 1QVGD 1N8RF 1VQ6D 4WFAD 5H1SH 4WCED 1K8AF 4WFND 1YJWD 1VQ5D 1M1KF 2ZJQD 5DM7D 1S72D 5MLCG 1VQ9D 2PZZA 3G4SD 2OTJD 1VQMD 3J7ZF 3CCSD 3DLLD 2QA4D 3CCLD 1W2BD 1QVFD 2ZJRD 1YITD 3CCQD 3I55D 3CCED 5GAGF 4IOCD 1NJIF 3CD6D 3CMED 4U67D 1YI2D 3I56D 1YJND 4WF9D 3CCUD 1VQND 3PIOD 4IO9D 2WNYA 3CMAD 1VQ7D 1YIJD 1JJ2D 3CC2D 1K9MF 3G6ED 1M90F 5GAHF 4IOAD 4UY8F 3CC4D 1YHQD 3G71D 1IQ4A 3CCVD 5GADF 3OW2D 1YJ9D 1KD1F 1VQLD 1Q81F 1VQKD 3CCRD 2NRQA 3CPWD 3CC7D 5DM6D 1VQOD 1MJIA 1Q86F 3CXCD 3CCMD 5GAEF 1Q7YF 2ZJPD 1Q82F 1KC8F 2NWUA 2OTLD 1K73F 1VQ4D 5JVGD 3CCJD 3C9GA 5JVHD 5HL7D 4WFBD 3CF5D 3D7AA 1KQSD 2OGKA 1VQ8D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QEX D;  1VQP D;  3PIP D;  1QVG D;  1N8R F;  1VQ6 D;  4WFA D;  5H1S H;  4WCE D;  1K8A F;  4WFN D;  1YJW D;  1VQ5 D;  1M1K F;  2ZJQ D;  5DM7 D;  1S72 D;  5MLC G;  1VQ9 D;  2PZZ A;  3G4S D;  2OTJ D;  1VQM D;  3J7Z F;  3CCS D;  3DLL D;  2QA4 D;  3CCL D;  1W2B D;  1QVF D;  2ZJR D;  1YIT D;  3CCQ D;  3I55 D;  3CCE D;  5GAG F;  4IOC D;  1NJI F;  3CD6 D;  3CME D;  4U67 D;  1YI2 D;  3I56 D;  1YJN D;  4WF9 D;  3CCU D;  1VQN D;  3PIO D;  4IO9 D;  2WNY A;  3CMA D;  1VQ7 D;  1YIJ D;  1JJ2 D;  3CC2 D;  1K9M F;  3G6E D;  1M90 F;  5GAH F;  4IOA D;  4UY8 F;  3CC4 D;  1YHQ D;  3G71 D;  1IQ4 A;  3CCV D;  5GAD F;  3OW2 D;  1YJ9 D;  1KD1 F;  1VQL D;  1Q81 F;  1VQK D;  3CCR D;  2NRQ A;  3CPW D;  3CC7 D;  5DM6 D;  1VQO D;  1MJI A;  1Q86 F;  3CXC D;  3CCM D;  5GAE F;  1Q7Y F;  2ZJP D;  1Q82 F;  1KC8 F;  2NWU A;  2OTL D;  1K73 F;  1VQ4 D;  5JVG D;  3CCJ D;  3C9G A;  5JVH D;  5HL7 D;  4WFB D;  3CF5 D;  3D7A A;  1KQS D;  2OGK A;  1VQ8 D; 
#chains in the Genus database with same CATH topology
 2QEX D;  1VQP D;  3PIP D;  1QVG D;  1N8R F;  1VQ6 D;  4WFA D;  5H1S H;  4WCE D;  1K8A F;  4WFN D;  1YJW D;  1VQ5 D;  1M1K F;  2ZJQ D;  5DM7 D;  1S72 D;  5MLC G;  1VQ9 D;  2PZZ A;  3G4S D;  2OTJ D;  1VQM D;  3J7Z F;  3CCS D;  3DLL D;  2QA4 D;  3CCL D;  1W2B D;  1QVF D;  2ZJR D;  1YIT D;  3CCQ D;  3I55 D;  3CCE D;  5GAG F;  4IOC D;  1NJI F;  3CD6 D;  3CME D;  4U67 D;  1YI2 D;  3I56 D;  1YJN D;  4WF9 D;  3CCU D;  1VQN D;  3PIO D;  4IO9 D;  2WNY A;  3CMA D;  1VQ7 D;  1YIJ D;  1JJ2 D;  3CC2 D;  1K9M F;  3G6E D;  1M90 F;  5GAH F;  4IOA D;  4UY8 F;  3CC4 D;  1YHQ D;  3G71 D;  1IQ4 A;  3CCV D;  5GAD F;  3OW2 D;  1YJ9 D;  1KD1 F;  1VQL D;  1Q81 F;  1VQK D;  3CCR D;  2NRQ A;  3CPW D;  3CC7 D;  5DM6 D;  1VQO D;  1MJI A;  1Q86 F;  3CXC D;  3CCM D;  5GAE F;  1Q7Y F;  2ZJP D;  1Q82 F;  1KC8 F;  2NWU A;  2OTL D;  1K73 F;  1VQ4 D;  5JVG D;  3CCJ D;  3C9G A;  5JVH D;  5HL7 D;  4WFB D;  3CF5 D;  3D7A A;  1KQS D;  2OGK A;  1VQ8 D; 
#chains in the Genus database with same CATH homology
 2QEX D;  1VQP D;  3PIP D;  1QVG D;  1N8R F;  1VQ6 D;  4WFA D;  5H1S H;  4WCE D;  1K8A F;  4WFN D;  1YJW D;  1VQ5 D;  1M1K F;  2ZJQ D;  5DM7 D;  1S72 D;  5MLC G;  1VQ9 D;  2PZZ A;  3G4S D;  2OTJ D;  1VQM D;  3J7Z F;  3CCS D;  3DLL D;  2QA4 D;  3CCL D;  1W2B D;  1QVF D;  2ZJR D;  1YIT D;  3CCQ D;  3I55 D;  3CCE D;  5GAG F;  4IOC D;  1NJI F;  3CD6 D;  3CME D;  4U67 D;  1YI2 D;  3I56 D;  1YJN D;  4WF9 D;  3CCU D;  1VQN D;  3PIO D;  4IO9 D;  2WNY A;  3CMA D;  1VQ7 D;  1YIJ D;  1JJ2 D;  3CC2 D;  1K9M F;  3G6E D;  1M90 F;  5GAH F;  4IOA D;  4UY8 F;  3CC4 D;  1YHQ D;  3G71 D;  1IQ4 A;  3CCV D;  5GAD F;  3OW2 D;  1YJ9 D;  1KD1 F;  1VQL D;  1Q81 F;  1VQK D;  3CCR D;  2NRQ A;  3CPW D;  3CC7 D;  5DM6 D;  1VQO D;  1MJI A;  1Q86 F;  3CXC D;  3CCM D;  5GAE F;  1Q7Y F;  2ZJP D;  1Q82 F;  1KC8 F;  2NWU A;  2OTL D;  1K73 F;  1VQ4 D;  5JVG D;  3CCJ D;  3C9G A;  5JVH D;  5HL7 D;  4WFB D;  3CF5 D;  3D7A A;  1KQS D;  2OGK A;  1VQ8 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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