4LIL | Genus

Total Genus 126

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	126
sequence length	380
structure length	370
Chain Sequence	PTELPELLKLYYRRLFPYSQYYRWLNYIKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSDICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESWDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIMLQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDATRDYKKTSLAPYVKVFEHFLENLDKS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 370 atoms

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase. pubmed doi rcsb
molecule keywords	DNA primase small subunit
molecule tags	Transferase
source organism	Homo sapiens
total genus	126
structure length	370
sequence length	380
ec nomenclature	ec 2.7.7.-:
pdb deposition date	2013-07-02

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01896	DNA_primase_S	DNA primase small subunit

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.920.30	Alpha Beta	Alpha-Beta Complex	DNA primase, PRIM domain	DNA primase, PRIM domain	4lilA00

4LIMA 4MM2A 4BPWA 4BPXA 4MHQA 4LIKA 5EXRA 4LILA 4BPUA 2FAOA 1ZT2A 2FARA 4RR2A 2FAQA
chains in the Genus database with same CATH superfamily

1V34A 4LIMA 4MM2A 4BPWA 4BPXA 4MHQA 1G71A 2ATZA 4LIKA 4RR2A 5EXRA 1V33A 4BPUA 2FAOA 1ZT2A 2FARA 4LILA 2FAQA
chains in the Genus database with same CATH topology

1V34A 4LIMA 4MM2A 4BPWA 4BPXA 4MHQA 1G71A 4LIKA 4RR2A 5EXRA 1V33A 4BPUA 2FAOA 1ZT2A 2FARA 4LILA 2FAQA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4LIM A;  4MM2 A;  4BPW A;  4BPX A;  4MHQ A;  4LIK A;  5EXR A;  4LIL A;  4BPU A;  2FAO A;  1ZT2 A;  2FAR A;  4RR2 A;  2FAQ A; 
#chains in the Genus database with same CATH topology
 1V34 A;  4LIM A;  4MM2 A;  4BPW A;  4BPX A;  4MHQ A;  1G71 A;  2ATZ A;  4LIK A;  4RR2 A;  5EXR A;  1V33 A;  4BPU A;  2FAO A;  1ZT2 A;  2FAR A;  4LIL A;  2FAQ A; 
#chains in the Genus database with same CATH homology
 1V34 A;  4LIM A;  4MM2 A;  4BPW A;  4BPX A;  4MHQ A;  1G71 A;  4LIK A;  4RR2 A;  5EXR A;  1V33 A;  4BPU A;  2FAO A;  1ZT2 A;  2FAR A;  4LIL A;  2FAQ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4LILA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations