4MHQ | Genus

Total Genus 134

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	134
sequence length	419
structure length	400
Chain Sequence	METFDPTELPELLKLYYRRLFPYSQYYRWLNYGGVIKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESWDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIMLQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAITRDYKKTSLAPYVKVFEHFLENLDKSRKGELLKKSDLQKD

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal structure of human primase catalytic subunit rcsb
molecule keywords	DNA primase small subunit
molecule tags	Replication
source organism	Homo sapiens
total genus	134
structure length	400
sequence length	419
ec nomenclature	ec 2.7.7.-:
pdb deposition date	2013-08-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01896	DNA_primase_S	DNA primase small subunit

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.920.30	Alpha Beta	Alpha-Beta Complex	DNA primase, PRIM domain	DNA primase, PRIM domain	4mhqA00

2FAQA 2FAOA 4LIMA 4MM2A 4MHQA 5EXRA 4BPXA 4BPWA 4RR2A 4LIKA 1ZT2A 2FARA 4LILA 4BPUA
chains in the Genus database with same CATH superfamily

1V33A 2FAQA 2FAOA 4LIMA 4MM2A 2ATZA 1V34A 4MHQA 5EXRA 4BPXA 1G71A 4BPWA 4RR2A 4LIKA 1ZT2A 2FARA 4LILA 4BPUA
chains in the Genus database with same CATH topology

1V33A 2FAQA 2FAOA 4LIMA 4MM2A 1V34A 4MHQA 5EXRA 4BPXA 1G71A 4BPWA 4RR2A 4LIKA 1ZT2A 2FARA 4LILA 4BPUA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2FAQ A;  2FAO A;  4LIM A;  4MM2 A;  4MHQ A;  5EXR A;  4BPX A;  4BPW A;  4RR2 A;  4LIK A;  1ZT2 A;  2FAR A;  4LIL A;  4BPU A; 
#chains in the Genus database with same CATH topology
 1V33 A;  2FAQ A;  2FAO A;  4LIM A;  4MM2 A;  2ATZ A;  1V34 A;  4MHQ A;  5EXR A;  4BPX A;  1G71 A;  4BPW A;  4RR2 A;  4LIK A;  1ZT2 A;  2FAR A;  4LIL A;  4BPU A; 
#chains in the Genus database with same CATH homology
 1V33 A;  2FAQ A;  2FAO A;  4LIM A;  4MM2 A;  1V34 A;  4MHQ A;  5EXR A;  4BPX A;  1G71 A;  4BPW A;  4RR2 A;  4LIK A;  1ZT2 A;  2FAR A;  4LIL A;  4BPU A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4MHQA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations