4RR2 | Genus

Total Genus 131

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	131
sequence length	415
structure length	389
Chain Sequence	METFDPTELPELLKLYYRRLFPYSQYYRWLNYGGVIKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESWDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNWLEWEIMLQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAIHRTRDYKKTSLAPYVKVFEHFLENLDKSRKGELLKKSD

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal structure of the human primase. pubmed doi rcsb
molecule keywords	DNA primase small subunit
molecule tags	Transferase
source organism	Homo sapiens
total genus	131
structure length	389
sequence length	415
chains with identical sequence	C
ec nomenclature	ec 2.7.7.-:
pdb deposition date	2014-11-05

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01896	DNA_primase_S	DNA primase small subunit

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.920.30	Alpha Beta	Alpha-Beta Complex	DNA primase, PRIM domain	DNA primase, PRIM domain	4rr2A00

4LILA 2FAOA 2FARA 4LIMA 4MHQA 1ZT2A 4BPWA 4BPUA 4LIKA 2FAQA 4MM2A 4BPXA 4RR2A 5EXRA
chains in the Genus database with same CATH superfamily

4LILA 1V34A 2FAOA 4MHQA 4LIMA 1V33A 1ZT2A 2FAQA 1G71A 4BPWA 4LIKA 2ATZA 4BPUA 2FARA 4MM2A 4BPXA 4RR2A 5EXRA
chains in the Genus database with same CATH topology

4LILA 1V34A 2FAOA 4MHQA 4LIMA 1V33A 1ZT2A 2FAQA 1G71A 4BPWA 4LIKA 4BPUA 2FARA 4MM2A 4BPXA 4RR2A 5EXRA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4LIL A;  2FAO A;  2FAR A;  4LIM A;  4MHQ A;  1ZT2 A;  4BPW A;  4BPU A;  4LIK A;  2FAQ A;  4MM2 A;  4BPX A;  4RR2 A;  5EXR A; 
#chains in the Genus database with same CATH topology
 4LIL A;  1V34 A;  2FAO A;  4MHQ A;  4LIM A;  1V33 A;  1ZT2 A;  2FAQ A;  1G71 A;  4BPW A;  4LIK A;  2ATZ A;  4BPU A;  2FAR A;  4MM2 A;  4BPX A;  4RR2 A;  5EXR A; 
#chains in the Genus database with same CATH homology
 4LIL A;  1V34 A;  2FAO A;  4MHQ A;  4LIM A;  1V33 A;  1ZT2 A;  2FAQ A;  1G71 A;  4BPW A;  4LIK A;  4BPU A;  2FAR A;  4MM2 A;  4BPX A;  4RR2 A;  5EXR A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4RR2A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations