4UI2D

Crystal structure of the ternary rgmb-bmp2-neo1 complex
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
156
structure length
156
Chain Sequence
PHLRTFKDNFQTCKVEGAWPLIDNNYLSVQVTNVPVVPGSSATATNKITIIFKAHHGCTDQKVYQAVTDDLPAAFVDGTTSGGDSDAKSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPEDLAMSYEESQDLQLCVNGCPLSERIDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords NEOGENIN
total genus 36
structure length 156
sequence length 156
ec nomenclature
pdb deposition date 2015-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF06534 RGM_C Repulsive guidance molecule (RGM) C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1000.10 Alpha Beta 3-Layer(aba) Sandwich Protein Transport Mog1p; Chain A Mog1/PsbP, alpha/beta/alpha sandwich 4ui2D00
4RTHA 2LNJA 1EQ6A 1TU1A 2VU4A 4UI2D 3V7BA 4BQ6D 3JCUP 1V2BA 4RTIA 1JHSA 3LYDA 2XB3A 4BQ8C 3HLZA
chains in the Genus database with same CATH superfamily
2LNJA 1TU1A 4N88B 4UI2D 3V7BA 4BQ6D 4OUHA 4L9CA 1EQ6A 2VU4A 4ESQA 4RTIA 3LYDA 4N7SB 4RTHA 3NR5A 1V2BA 4L9HA 1JHSA 2XB3A 4M5FB 1VR8A 3WA5B 2VT8A 3JCUP 4N80B 4LUQC 3BCYA 4BQ8C 3HLZA
chains in the Genus database with same CATH topology
4RTHA 2LNJA 1EQ6A 1TU1A 2VU4A 4UI2D 3V7BA 4BQ6D 3JCUP 1V2BA 4RTIA 1JHSA 3LYDA 2XB3A 4BQ8C 3HLZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RTH A;  2LNJ A;  1EQ6 A;  1TU1 A;  2VU4 A;  4UI2 D;  3V7B A;  4BQ6 D;  3JCU P;  1V2B A;  4RTI A;  1JHS A;  3LYD A;  2XB3 A;  4BQ8 C;  3HLZ A; 
#chains in the Genus database with same CATH topology
 2LNJ A;  1TU1 A;  4N88 B;  4UI2 D;  3V7B A;  4BQ6 D;  4OUH A;  4L9C A;  1EQ6 A;  2VU4 A;  4ESQ A;  4RTI A;  3LYD A;  4N7S B;  4RTH A;  3NR5 A;  1V2B A;  4L9H A;  1JHS A;  2XB3 A;  4M5F B;  1VR8 A;  3WA5 B;  2VT8 A;  3JCU P;  4N80 B;  4LUQ C;  3BCY A;  4BQ8 C;  3HLZ A; 
#chains in the Genus database with same CATH homology
 4RTH A;  2LNJ A;  1EQ6 A;  1TU1 A;  2VU4 A;  4UI2 D;  3V7B A;  4BQ6 D;  3JCU P;  1V2B A;  4RTI A;  1JHS A;  3LYD A;  2XB3 A;  4BQ8 C;  3HLZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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