4IOAD

Crystal structure of compound 4e bound to large ribosomal subunit (50s) from deinococcus radiodurans
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
177
structure length
177
Chain Sequence
QLKTKYNDQVRPALMQQFGYSSVMAVPRIEKIVVNEGLGSSKEDSKAIDKAAKELALITLQKPIITKAKKSISNFKLRQGMPVGIKVTLRGERMYVFLEKLINIGLPRIRDFRGINPNAFDGRGNYNLGIKEQLIFPEITYDMVDKTRGMDITIVTTAKTDEEARALLQSMGLPFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates.
pubmed doi rcsb
molecule tags Ribosome/ribosome inhibitor
molecule keywords 23S ribosomal RNA
total genus 24
structure length 177
sequence length 177
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 4ioaD00
4WFBD 1S72D 1IQ4A 5H1SH 5DM6D 3G6ED 1KD1F 3CCRD 4WFAD 2ZJRD 1VQ6D 4WF9D 1VQ9D 4UY8F 3CC2D 1QVFD 1Q7YF 1VQMD 3CXCD 2OGKA 1YJ9D 5HL7D 3CCUD 1VQ5D 3CPWD 3I55D 1VQKD 5MLCG 1YI2D 1VQLD 1YIJD 3DLLD 5GAEF 1W2BD 1YHQD 1JJ2D 3CF5D 3G71D 1M90F 1VQPD 2ZJPD 2NWUA 2QA4D 3C9GA 1N8RF 3G4SD 2PZZA 3PIOD 3CCVD 1K8AF 1K73F 1KC8F 1VQ4D 1VQ7D 1YITD 1YJND 3CC7D 5JVGD 3I56D 2OTJD 5JVHD 4U67D 1KQSD 2WNYA 5GAHF 1YJWD 1MJIA 1Q86F 1QVGD 5GAGF 1Q81F 4IO9D 3CCMD 3CC4D 2OTLD 4IOCD 3CCED 3CCLD 3OW2D 1K9MF 1VQND 3CMAD 1NJIF 3D7AA 4WFND 4WCED 3PIPD 5GADF 3CCJD 1M1KF 3J7ZF 3CD6D 4IOAD 2ZJQD 1VQ8D 2QEXD 1Q82F 2NRQA 3CCSD 5DM7D 3CCQD 3CMED 1VQOD
chains in the Genus database with same CATH superfamily
4WFBD 1S72D 1IQ4A 5H1SH 5DM6D 3G6ED 1KD1F 3CCRD 4WFAD 2ZJRD 1VQ6D 4WF9D 1VQ9D 4UY8F 3CC2D 1QVFD 1Q7YF 1VQMD 3CXCD 2OGKA 1YJ9D 5HL7D 3CCUD 1VQ5D 3CPWD 3I55D 1VQKD 5MLCG 1YI2D 1VQLD 1YIJD 3DLLD 5GAEF 1W2BD 1YHQD 1JJ2D 3CF5D 3G71D 1M90F 1VQPD 2ZJPD 2NWUA 2QA4D 3C9GA 1N8RF 3G4SD 2PZZA 3PIOD 3CCVD 1K8AF 1K73F 1KC8F 1VQ4D 1VQ7D 1YITD 1YJND 3CC7D 5JVGD 3I56D 2OTJD 5JVHD 4U67D 1KQSD 2WNYA 5GAHF 1YJWD 1MJIA 1Q86F 1QVGD 5GAGF 1Q81F 4IO9D 3CCMD 3CC4D 2OTLD 4IOCD 3CCED 3CCLD 3OW2D 1K9MF 1VQND 3CMAD 1NJIF 3D7AA 4WFND 4WCED 3PIPD 5GADF 3CCJD 1M1KF 3J7ZF 3CD6D 4IOAD 2ZJQD 1VQ8D 2QEXD 1Q82F 2NRQA 3CCSD 5DM7D 3CCQD 3CMED 1VQOD
chains in the Genus database with same CATH topology
4WFBD 1S72D 1IQ4A 5H1SH 5DM6D 3G6ED 1KD1F 3CCRD 4WFAD 2ZJRD 1VQ6D 4WF9D 1VQ9D 4UY8F 3CC2D 1QVFD 1Q7YF 1VQMD 3CXCD 2OGKA 1YJ9D 5HL7D 3CCUD 1VQ5D 3CPWD 3I55D 1VQKD 5MLCG 1YI2D 1VQLD 1YIJD 3DLLD 5GAEF 1W2BD 1YHQD 1JJ2D 3CF5D 3G71D 1M90F 1VQPD 2ZJPD 2NWUA 2QA4D 3C9GA 1N8RF 3G4SD 2PZZA 3PIOD 3CCVD 1K8AF 1K73F 1KC8F 1VQ4D 1VQ7D 1YITD 1YJND 3CC7D 5JVGD 3I56D 2OTJD 5JVHD 4U67D 1KQSD 2WNYA 5GAHF 1YJWD 1MJIA 1Q86F 1QVGD 5GAGF 1Q81F 4IO9D 3CCMD 3CC4D 2OTLD 4IOCD 3CCED 3CCLD 3OW2D 1K9MF 1VQND 3CMAD 1NJIF 3D7AA 4WFND 4WCED 3PIPD 5GADF 3CCJD 1M1KF 3J7ZF 3CD6D 4IOAD 2ZJQD 1VQ8D 2QEXD 1Q82F 2NRQA 3CCSD 5DM7D 3CCQD 3CMED 1VQOD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFB D;  1S72 D;  1IQ4 A;  5H1S H;  5DM6 D;  3G6E D;  1KD1 F;  3CCR D;  4WFA D;  2ZJR D;  1VQ6 D;  4WF9 D;  1VQ9 D;  4UY8 F;  3CC2 D;  1QVF D;  1Q7Y F;  1VQM D;  3CXC D;  2OGK A;  1YJ9 D;  5HL7 D;  3CCU D;  1VQ5 D;  3CPW D;  3I55 D;  1VQK D;  5MLC G;  1YI2 D;  1VQL D;  1YIJ D;  3DLL D;  5GAE F;  1W2B D;  1YHQ D;  1JJ2 D;  3CF5 D;  3G71 D;  1M90 F;  1VQP D;  2ZJP D;  2NWU A;  2QA4 D;  3C9G A;  1N8R F;  3G4S D;  2PZZ A;  3PIO D;  3CCV D;  1K8A F;  1K73 F;  1KC8 F;  1VQ4 D;  1VQ7 D;  1YIT D;  1YJN D;  3CC7 D;  5JVG D;  3I56 D;  2OTJ D;  5JVH D;  4U67 D;  1KQS D;  2WNY A;  5GAH F;  1YJW D;  1MJI A;  1Q86 F;  1QVG D;  5GAG F;  1Q81 F;  4IO9 D;  3CCM D;  3CC4 D;  2OTL D;  4IOC D;  3CCE D;  3CCL D;  3OW2 D;  1K9M F;  1VQN D;  3CMA D;  1NJI F;  3D7A A;  4WFN D;  4WCE D;  3PIP D;  5GAD F;  3CCJ D;  1M1K F;  3J7Z F;  3CD6 D;  4IOA D;  2ZJQ D;  1VQ8 D;  2QEX D;  1Q82 F;  2NRQ A;  3CCS D;  5DM7 D;  3CCQ D;  3CME D;  1VQO D; 
#chains in the Genus database with same CATH topology
 4WFB D;  1S72 D;  1IQ4 A;  5H1S H;  5DM6 D;  3G6E D;  1KD1 F;  3CCR D;  4WFA D;  2ZJR D;  1VQ6 D;  4WF9 D;  1VQ9 D;  4UY8 F;  3CC2 D;  1QVF D;  1Q7Y F;  1VQM D;  3CXC D;  2OGK A;  1YJ9 D;  5HL7 D;  3CCU D;  1VQ5 D;  3CPW D;  3I55 D;  1VQK D;  5MLC G;  1YI2 D;  1VQL D;  1YIJ D;  3DLL D;  5GAE F;  1W2B D;  1YHQ D;  1JJ2 D;  3CF5 D;  3G71 D;  1M90 F;  1VQP D;  2ZJP D;  2NWU A;  2QA4 D;  3C9G A;  1N8R F;  3G4S D;  2PZZ A;  3PIO D;  3CCV D;  1K8A F;  1K73 F;  1KC8 F;  1VQ4 D;  1VQ7 D;  1YIT D;  1YJN D;  3CC7 D;  5JVG D;  3I56 D;  2OTJ D;  5JVH D;  4U67 D;  1KQS D;  2WNY A;  5GAH F;  1YJW D;  1MJI A;  1Q86 F;  1QVG D;  5GAG F;  1Q81 F;  4IO9 D;  3CCM D;  3CC4 D;  2OTL D;  4IOC D;  3CCE D;  3CCL D;  3OW2 D;  1K9M F;  1VQN D;  3CMA D;  1NJI F;  3D7A A;  4WFN D;  4WCE D;  3PIP D;  5GAD F;  3CCJ D;  1M1K F;  3J7Z F;  3CD6 D;  4IOA D;  2ZJQ D;  1VQ8 D;  2QEX D;  1Q82 F;  2NRQ A;  3CCS D;  5DM7 D;  3CCQ D;  3CME D;  1VQO D; 
#chains in the Genus database with same CATH homology
 4WFB D;  1S72 D;  1IQ4 A;  5H1S H;  5DM6 D;  3G6E D;  1KD1 F;  3CCR D;  4WFA D;  2ZJR D;  1VQ6 D;  4WF9 D;  1VQ9 D;  4UY8 F;  3CC2 D;  1QVF D;  1Q7Y F;  1VQM D;  3CXC D;  2OGK A;  1YJ9 D;  5HL7 D;  3CCU D;  1VQ5 D;  3CPW D;  3I55 D;  1VQK D;  5MLC G;  1YI2 D;  1VQL D;  1YIJ D;  3DLL D;  5GAE F;  1W2B D;  1YHQ D;  1JJ2 D;  3CF5 D;  3G71 D;  1M90 F;  1VQP D;  2ZJP D;  2NWU A;  2QA4 D;  3C9G A;  1N8R F;  3G4S D;  2PZZ A;  3PIO D;  3CCV D;  1K8A F;  1K73 F;  1KC8 F;  1VQ4 D;  1VQ7 D;  1YIT D;  1YJN D;  3CC7 D;  5JVG D;  3I56 D;  2OTJ D;  5JVH D;  4U67 D;  1KQS D;  2WNY A;  5GAH F;  1YJW D;  1MJI A;  1Q86 F;  1QVG D;  5GAG F;  1Q81 F;  4IO9 D;  3CCM D;  3CC4 D;  2OTL D;  4IOC D;  3CCE D;  3CCL D;  3OW2 D;  1K9M F;  1VQN D;  3CMA D;  1NJI F;  3D7A A;  4WFN D;  4WCE D;  3PIP D;  5GAD F;  3CCJ D;  1M1K F;  3J7Z F;  3CD6 D;  4IOA D;  2ZJQ D;  1VQ8 D;  2QEX D;  1Q82 F;  2NRQ A;  3CCS D;  5DM7 D;  3CCQ D;  3CME D;  1VQO D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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