5HL7D

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with lefamulin
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
165
structure length
165
Chain Sequence
KEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAVQNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANTDEEAREL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2
total genus 21
structure length 165
sequence length 165
ec nomenclature
pdb deposition date 2016-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00281 Ribosomal_L5 Ribosomal protein L5
D PF00673 Ribosomal_L5_C ribosomal L5P family C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1440.10 Alpha Beta 2-Layer Sandwich 50s Ribosomal Protein L5; Chain: A, 50s Ribosomal Protein L5; Chain: A, 5hl7D00
3D7AA 1VQLD 3C9GA 4IOCD 3G4SD 3CPWD 1QVFD 4WF9D 4WFAD 3OW2D 1Q7YF 2NWUA 1M90F 1VQKD 1VQ8D 5HL7D 1YJWD 1Q86F 1VQ6D 3CXCD 1W2BD 2NRQA 3CMED 3I56D 3PIPD 5GADF 5DM7D 3CCQD 2QA4D 3CCSD 2ZJQD 3CC2D 2PZZA 3CCED 1VQ9D 3I55D 1KQSD 4UY8F 1S72D 1IQ4A 1YJ9D 1M1KF 2ZJRD 1Q81F 4U67D 4WFND 5H1SH 3G71D 1K73F 4IO9D 4IOAD 1MJIA 2WNYA 3DLLD 3CD6D 5GAGF 5MLCG 1YI2D 3CCVD 3CC4D 3J7ZF 5JVGD 3PIOD 3CCUD 1KD1F 1VQ4D 1Q82F 2OGKA 2ZJPD 3CF5D 3CCRD 1VQOD 1NJIF 1K8AF 4WFBD 1KC8F 5DM6D 3CCJD 1YITD 2QEXD 2OTLD 3CMAD 2OTJD 4WCED 1VQ5D 5JVHD 1JJ2D 3CCMD 1YJND 1VQPD 1VQMD 1N8RF 1VQND 3G6ED 5GAEF 3CC7D 1K9MF 1YIJD 3CCLD 1VQ7D 1YHQD 1QVGD 5GAHF
chains in the Genus database with same CATH superfamily
3D7AA 1VQLD 3C9GA 4IOCD 3G4SD 3CPWD 1QVFD 4WF9D 4WFAD 3OW2D 1Q7YF 2NWUA 1M90F 1VQKD 1VQ8D 5HL7D 1YJWD 1Q86F 1VQ6D 3CXCD 1W2BD 2NRQA 3CMED 3I56D 3PIPD 5GADF 5DM7D 3CCQD 2QA4D 3CCSD 2ZJQD 3CC2D 2PZZA 3CCED 1VQ9D 3I55D 1KQSD 4UY8F 1S72D 1IQ4A 1YJ9D 1M1KF 2ZJRD 1Q81F 4U67D 4WFND 5H1SH 3G71D 1K73F 4IO9D 4IOAD 1MJIA 2WNYA 3DLLD 3CD6D 5GAGF 5MLCG 1YI2D 3CCVD 3CC4D 3J7ZF 5JVGD 3PIOD 3CCUD 1KD1F 1VQ4D 1Q82F 2OGKA 2ZJPD 3CF5D 3CCRD 1VQOD 1NJIF 1K8AF 4WFBD 1KC8F 5DM6D 3CCJD 1YITD 2QEXD 2OTLD 3CMAD 2OTJD 4WCED 1VQ5D 5JVHD 1JJ2D 3CCMD 1YJND 1VQPD 1VQMD 1N8RF 1VQND 3G6ED 5GAEF 3CC7D 1K9MF 1YIJD 3CCLD 1VQ7D 1YHQD 1QVGD 5GAHF
chains in the Genus database with same CATH topology
3D7AA 1VQLD 3C9GA 4IOCD 3G4SD 3CPWD 1QVFD 4WF9D 4WFAD 3OW2D 1Q7YF 2NWUA 1M90F 1VQKD 1VQ8D 5HL7D 1YJWD 1Q86F 1VQ6D 3CXCD 1W2BD 2NRQA 3CMED 3I56D 3PIPD 5GADF 5DM7D 3CCQD 2QA4D 3CCSD 2ZJQD 3CC2D 2PZZA 3CCED 1VQ9D 3I55D 1KQSD 4UY8F 1S72D 1IQ4A 1YJ9D 1M1KF 2ZJRD 1Q81F 4U67D 4WFND 5H1SH 3G71D 1K73F 4IO9D 4IOAD 1MJIA 2WNYA 3DLLD 3CD6D 5GAGF 5MLCG 1YI2D 3CCVD 3CC4D 3J7ZF 5JVGD 3PIOD 3CCUD 1KD1F 1VQ4D 1Q82F 2OGKA 2ZJPD 3CF5D 3CCRD 1VQOD 1NJIF 1K8AF 4WFBD 1KC8F 5DM6D 3CCJD 1YITD 2QEXD 2OTLD 3CMAD 2OTJD 4WCED 1VQ5D 5JVHD 1JJ2D 3CCMD 1YJND 1VQPD 1VQMD 1N8RF 1VQND 3G6ED 5GAEF 3CC7D 1K9MF 1YIJD 3CCLD 1VQ7D 1YHQD 1QVGD 5GAHF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D7A A;  1VQL D;  3C9G A;  4IOC D;  3G4S D;  3CPW D;  1QVF D;  4WF9 D;  4WFA D;  3OW2 D;  1Q7Y F;  2NWU A;  1M90 F;  1VQK D;  1VQ8 D;  5HL7 D;  1YJW D;  1Q86 F;  1VQ6 D;  3CXC D;  1W2B D;  2NRQ A;  3CME D;  3I56 D;  3PIP D;  5GAD F;  5DM7 D;  3CCQ D;  2QA4 D;  3CCS D;  2ZJQ D;  3CC2 D;  2PZZ A;  3CCE D;  1VQ9 D;  3I55 D;  1KQS D;  4UY8 F;  1S72 D;  1IQ4 A;  1YJ9 D;  1M1K F;  2ZJR D;  1Q81 F;  4U67 D;  4WFN D;  5H1S H;  3G71 D;  1K73 F;  4IO9 D;  4IOA D;  1MJI A;  2WNY A;  3DLL D;  3CD6 D;  5GAG F;  5MLC G;  1YI2 D;  3CCV D;  3CC4 D;  3J7Z F;  5JVG D;  3PIO D;  3CCU D;  1KD1 F;  1VQ4 D;  1Q82 F;  2OGK A;  2ZJP D;  3CF5 D;  3CCR D;  1VQO D;  1NJI F;  1K8A F;  4WFB D;  1KC8 F;  5DM6 D;  3CCJ D;  1YIT D;  2QEX D;  2OTL D;  3CMA D;  2OTJ D;  4WCE D;  1VQ5 D;  5JVH D;  1JJ2 D;  3CCM D;  1YJN D;  1VQP D;  1VQM D;  1N8R F;  1VQN D;  3G6E D;  5GAE F;  3CC7 D;  1K9M F;  1YIJ D;  3CCL D;  1VQ7 D;  1YHQ D;  1QVG D;  5GAH F; 
#chains in the Genus database with same CATH topology
 3D7A A;  1VQL D;  3C9G A;  4IOC D;  3G4S D;  3CPW D;  1QVF D;  4WF9 D;  4WFA D;  3OW2 D;  1Q7Y F;  2NWU A;  1M90 F;  1VQK D;  1VQ8 D;  5HL7 D;  1YJW D;  1Q86 F;  1VQ6 D;  3CXC D;  1W2B D;  2NRQ A;  3CME D;  3I56 D;  3PIP D;  5GAD F;  5DM7 D;  3CCQ D;  2QA4 D;  3CCS D;  2ZJQ D;  3CC2 D;  2PZZ A;  3CCE D;  1VQ9 D;  3I55 D;  1KQS D;  4UY8 F;  1S72 D;  1IQ4 A;  1YJ9 D;  1M1K F;  2ZJR D;  1Q81 F;  4U67 D;  4WFN D;  5H1S H;  3G71 D;  1K73 F;  4IO9 D;  4IOA D;  1MJI A;  2WNY A;  3DLL D;  3CD6 D;  5GAG F;  5MLC G;  1YI2 D;  3CCV D;  3CC4 D;  3J7Z F;  5JVG D;  3PIO D;  3CCU D;  1KD1 F;  1VQ4 D;  1Q82 F;  2OGK A;  2ZJP D;  3CF5 D;  3CCR D;  1VQO D;  1NJI F;  1K8A F;  4WFB D;  1KC8 F;  5DM6 D;  3CCJ D;  1YIT D;  2QEX D;  2OTL D;  3CMA D;  2OTJ D;  4WCE D;  1VQ5 D;  5JVH D;  1JJ2 D;  3CCM D;  1YJN D;  1VQP D;  1VQM D;  1N8R F;  1VQN D;  3G6E D;  5GAE F;  3CC7 D;  1K9M F;  1YIJ D;  3CCL D;  1VQ7 D;  1YHQ D;  1QVG D;  5GAH F; 
#chains in the Genus database with same CATH homology
 3D7A A;  1VQL D;  3C9G A;  4IOC D;  3G4S D;  3CPW D;  1QVF D;  4WF9 D;  4WFA D;  3OW2 D;  1Q7Y F;  2NWU A;  1M90 F;  1VQK D;  1VQ8 D;  5HL7 D;  1YJW D;  1Q86 F;  1VQ6 D;  3CXC D;  1W2B D;  2NRQ A;  3CME D;  3I56 D;  3PIP D;  5GAD F;  5DM7 D;  3CCQ D;  2QA4 D;  3CCS D;  2ZJQ D;  3CC2 D;  2PZZ A;  3CCE D;  1VQ9 D;  3I55 D;  1KQS D;  4UY8 F;  1S72 D;  1IQ4 A;  1YJ9 D;  1M1K F;  2ZJR D;  1Q81 F;  4U67 D;  4WFN D;  5H1S H;  3G71 D;  1K73 F;  4IO9 D;  4IOA D;  1MJI A;  2WNY A;  3DLL D;  3CD6 D;  5GAG F;  5MLC G;  1YI2 D;  3CCV D;  3CC4 D;  3J7Z F;  5JVG D;  3PIO D;  3CCU D;  1KD1 F;  1VQ4 D;  1Q82 F;  2OGK A;  2ZJP D;  3CF5 D;  3CCR D;  1VQO D;  1NJI F;  1K8A F;  4WFB D;  1KC8 F;  5DM6 D;  3CCJ D;  1YIT D;  2QEX D;  2OTL D;  3CMA D;  2OTJ D;  4WCE D;  1VQ5 D;  5JVH D;  1JJ2 D;  3CCM D;  1YJN D;  1VQP D;  1VQM D;  1N8R F;  1VQN D;  3G6E D;  5GAE F;  3CC7 D;  1K9M F;  1YIJ D;  3CCL D;  1VQ7 D;  1YHQ D;  1QVG D;  5GAH F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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