5KUQ | Genus

Total Genus 54

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	54
sequence length	164
structure length	164
Chain Sequence	VNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Isomerase
source organism	Homo sapiens
publication title	Conformational variation of proteins at room temperature is not dominated by radiation damage. pubmed doi rcsb
molecule keywords	Peptidyl-prolyl cis-trans isomerase A
total genus	54
structure length	164
sequence length	164
ec nomenclature	ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date	2016-07-13

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00160	Pro_isomerase	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.40.100.10	Mainly Beta	Beta Barrel	Cyclophilin	Cyclophilin-like	5kuqA00

2RMAA 1YNDA 1CWFA 1DYWA 2IGVA 4J59A 1ZKFA 2POYA 1MIKA 3CYHA 1CYNA 4FRVA 4YUHA 5KV5A 1CWBA 1NMKA 2X2AA 3R57A 3BKPA 2XGYB 1BCKA 3BT8A 4LQWA 2POEA 2X83B 3R4GA 5DUDA 3RCLA 1QNGA 3RDCA 3OPFA 5CCRA 2MC9A 2GW2A 1CWAA 1MF8C 4YUJA 2CK1A 3BO7A 4DGBA 1M9EA 2WFJA 3JB9d 3UCHA 1OCAA 4J5CX 4XNCA 4HY7A 3RCKX 4DGCA 4J5DX 5KV3A 4O8IA 4J5BA 3K0NA 2ESLA 5KV7A 3T1UA 3K0QA 5KUWA 3OEPA 1CWHA 3K0RA 5KURA 4J5AX 4TOTA 1E8KA 4N1RA 4FRUA 1XYHA 5KUQA 1H0PA 3RCGA 4N1NA 1Z81A 1CWCA 1XQ7A 2X7KA 4R3FA 2RS4A 3RCIX 1XO7A 5KUZA 4N1SA 3ICHA 1AK4A 1W74A 1AWRA 4JCPA 4ZSCA 1AWQA 3R54A 2BIUX 2X2CK 3K0MA 4DGDA 4YUOA 4YUIA 4IPZA 2FU0A 3MMLB 4O8HA 1VAIA 4S1EA 1W8MA 5KUNA 1AWTA 2ALFA 3PMPA 3RDDA 2WLWA 5CBTA 3RDAX 4YUPA 1AWSA 2BITX 2HQ6A 2X2DB 4N1QA 4DGEA 5KULA 2K7NA 5KV1A 5KV6A 1VDNA 5KV2A 4CYHA 4DGAA 1E3BA 5CBWA 2X25B 2C3BA 5F66A 1V9TA 1MZWA 2CFEA 1IHGA 5KUOA 2B71A 2IGWA 2R99A 4N1PA 1CWIA 2PHCB 3MMLA 4R3EA 4S1JA 1CWKA 4YUKA 5CCNA 5CCQA 5JHEA 1M9YA 1CWMA 1A33A 5KUUA 2MVZA 1W8LA 1AWUA 2CMTA 1QNHA 2HAQA 1M9XA 4N1OA 5CCSX 3O7TA 2RMCA 1C5FA 4J58A 4ZSDA 2HQJA 3RDBA 5KV4A 4JJMA 4EYVA 1LOPA 2A2NA 2PLUA 3S6MA 1M9DA 3RCFA 2P0OA 3ODIA 1M9CA 1QOIA 2RMBA 3K0OA 3K2CA 3OREA 1VBTA 2CPLA 5CYHA 1CWLA 1ZMFA 1XWNA 2Z6WA 1VBSA 1X7FA 2WFIA 1A58A 1M63C 2MZUA 3ICIA 5CBVA 4N1MA 1J2AA 5KUSA 5CBUA 1RMHA 2CYHA 3R56A 5KUVA 4YUGA 3VA7A 2OSEA 1W8VA 1ISTA 2OJUA 2ZP2A 4YULA 5LUDA 4YUMA 4E1QA 2N0TA 3CYSA 5A0EA 1CWJA 5KV0A 3RD9X 2NULA 1M9FA 3ODLA 3RFYA 1FGLA 4J5EX 2QERA 3K0PA 1CLHA 3R59A 1CWOA 3QYUA 2HE9A 4YUNA 4I9YA 1IIPA 3EOVA 1AWVA 2MS4A 3R49A 2OK3A 1ZKCA
chains in the Genus database with same CATH superfamily

2RMAA 1YNDA 1CWFA 1DYWA 2IGVA 4J59A 1ZKFA 2POYA 1MIKA 3CYHA 1CYNA 4FRVA 4YUHA 5KV5A 1CWBA 1NMKA 2X2AA 3R57A 3BKPA 2XGYB 1BCKA 3BT8A 4LQWA 2POEA 2X83B 3R4GA 5DUDA 3RCLA 1QNGA 3RDCA 3OPFA 5CCRA 2MC9A 2GW2A 1CWAA 1MF8C 4YUJA 2CK1A 3BO7A 4DGBA 1M9EA 2NNZA 2WFJA 3UCHA 1OCAA 4J5CX 4XNCA 4HY7A 3RCKX 4DGCA 4J5DX 5KV3A 4O8IA 4J5BA 3K0NA 2ESLA 5KV7A 3T1UA 3K0QA 5KUWA 3OEPA 1CWHA 3K0RA 5KURA 4J5AX 4TOTA 1E8KA 4N1RA 4FRUA 1XYHA 5KUQA 1H0PA 3RCGA 4N1NA 1Z81A 1CWCA 1XQ7A 2X7KA 4R3FA 2RS4A 3RCIX 1XO7A 5KUZA 4N1SA 3ICHA 1AK4A 1W74A 1AWRA 4JCPA 4ZSCA 1AWQA 3R54A 2BIUX 2X2CK 3K0MA 4DGDA 4YUOA 4YUIA 4IPZA 2FU0A 3MMLB 4O8HA 1VAIA 4S1EA 1W8MA 5KUNA 1AWTA 2ALFA 3PMPA 3RDDA 2WLWA 5CBTA 3JB9d 3RDAX 4YUPA 1AWSA 2BITX 2HQ6A 2X2DB 4N1QA 4DGEA 5KULA 2K7NA 5KV1A 5KV6A 1VDNA 5KV2A 4CYHA 4DGAA 1E3BA 5CBWA 2X25B 2C3BA 5F66A 1V9TA 1MZWA 2CFEA 1IHGA 5KUOA 2B71A 2IGWA 2R99A 4N1PA 1CWIA 2PHCB 3MMLA 4R3EA 4S1JA 1CWKA 4YUKA 5CCNA 5CCQA 5JHEA 1M9YA 1CWMA 1A33A 5KUUA 2MVZA 1W8LA 1AWUA 3KOPA 2CMTA 1QNHA 2HAQA 1M9XA 4N1OA 5CCSX 3O7TA 2RMCA 1C5FA 4J58A 4ZSDA 2HQJA 3RDBA 5KV4A 4JJMA 4EYVA 1LOPA 2A2NA 2PLUA 3S6MA 1M9DA 3RCFA 2P0OA 3ODIA 1M9CA 1QOIA 2RMBA 3K0OA 3K2CA 3OREA 1VBTA 2CPLA 5CYHA 1CWLA 1ZMFA 1XWNA 2Z6WA 1VBSA 1X7FA 2WFIA 1A58A 1M63C 2MZUA 3ICIA 5CBVA 4N1MA 1J2AA 5KUSA 5CBUA 1RMHA 2CYHA 3R56A 5KUVA 4YUGA 3VA7A 2OSEA 1ZX8A 1W8VA 1ISTA 2OJUA 2ZP2A 4YULA 5LUDA 4YUMA 4E1QA 2N0TA 3CYSA 5A0EA 1CWJA 5KV0A 3RD9X 2NULA 1M9FA 3ODLA 3RFYA 1FGLA 4J5EX 2QERA 3K0PA 1CLHA 3X27A 3R59A 1CWOA 2KA0A 3QYUA 2HE9A 4YUNA 4I9YA 1IIPA 3EOVA 1AWVA 2MS4A 3R49A 2OK3A 1ZKCA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2RMA A;  1YND A;  1CWF A;  1DYW A;  2IGV A;  4J59 A;  1ZKF A;  2POY A;  1MIK A;  3CYH A;  1CYN A;  4FRV A;  4YUH A;  5KV5 A;  1CWB A;  1NMK A;  2X2A A;  3R57 A;  3BKP A;  2XGY B;  1BCK A;  3BT8 A;  4LQW A;  2POE A;  2X83 B;  3R4G A;  5DUD A;  3RCL A;  1QNG A;  3RDC A;  3OPF A;  5CCR A;  2MC9 A;  2GW2 A;  1CWA A;  1MF8 C;  4YUJ A;  2CK1 A;  3BO7 A;  4DGB A;  1M9E A;  2WFJ A;  3JB9 d;  3UCH A;  1OCA A;  4J5C X;  4XNC A;  4HY7 A;  3RCK X;  4DGC A;  4J5D X;  5KV3 A;  4O8I A;  4J5B A;  3K0N A;  2ESL A;  5KV7 A;  3T1U A;  3K0Q A;  5KUW A;  3OEP A;  1CWH A;  3K0R A;  5KUR A;  4J5A X;  4TOT A;  1E8K A;  4N1R A;  4FRU A;  1XYH A;  5KUQ A;  1H0P A;  3RCG A;  4N1N A;  1Z81 A;  1CWC A;  1XQ7 A;  2X7K A;  4R3F A;  2RS4 A;  3RCI X;  1XO7 A;  5KUZ A;  4N1S A;  3ICH A;  1AK4 A;  1W74 A;  1AWR A;  4JCP A;  4ZSC A;  1AWQ A;  3R54 A;  2BIU X;  2X2C K;  3K0M A;  4DGD A;  4YUO A;  4YUI A;  4IPZ A;  2FU0 A;  3MML B;  4O8H A;  1VAI A;  4S1E A;  1W8M A;  5KUN A;  1AWT A;  2ALF A;  3PMP A;  3RDD A;  2WLW A;  5CBT A;  3RDA X;  4YUP A;  1AWS A;  2BIT X;  2HQ6 A;  2X2D B;  4N1Q A;  4DGE A;  5KUL A;  2K7N A;  5KV1 A;  5KV6 A;  1VDN A;  5KV2 A;  4CYH A;  4DGA A;  1E3B A;  5CBW A;  2X25 B;  2C3B A;  5F66 A;  1V9T A;  1MZW A;  2CFE A;  1IHG A;  5KUO A;  2B71 A;  2IGW A;  2R99 A;  4N1P A;  1CWI A;  2PHC B;  3MML A;  4R3E A;  4S1J A;  1CWK A;  4YUK A;  5CCN A;  5CCQ A;  5JHE A;  1M9Y A;  1CWM A;  1A33 A;  5KUU A;  2MVZ A;  1W8L A;  1AWU A;  2CMT A;  1QNH A;  2HAQ A;  1M9X A;  4N1O A;  5CCS X;  3O7T A;  2RMC A;  1C5F A;  4J58 A;  4ZSD A;  2HQJ A;  3RDB A;  5KV4 A;  4JJM A;  4EYV A;  1LOP A;  2A2N A;  2PLU A;  3S6M A;  1M9D A;  3RCF A;  2P0O A;  3ODI A;  1M9C A;  1QOI A;  2RMB A;  3K0O A;  3K2C A;  3ORE A;  1VBT A;  2CPL A;  5CYH A;  1CWL A;  1ZMF A;  1XWN A;  2Z6W A;  1VBS A;  1X7F A;  2WFI A;  1A58 A;  1M63 C;  2MZU A;  3ICI A;  5CBV A;  4N1M A;  1J2A A;  5KUS A;  5CBU A;  1RMH A;  2CYH A;  3R56 A;  5KUV A;  4YUG A;  3VA7 A;  2OSE A;  1W8V A;  1IST A;  2OJU A;  2ZP2 A;  4YUL A;  5LUD A;  4YUM A;  4E1Q A;  2N0T A;  3CYS A;  5A0E A;  1CWJ A;  5KV0 A;  3RD9 X;  2NUL A;  1M9F A;  3ODL A;  3RFY A;  1FGL A;  4J5E X;  2QER A;  3K0P A;  1CLH A;  3R59 A;  1CWO A;  3QYU A;  2HE9 A;  4YUN A;  4I9Y A;  1IIP A;  3EOV A;  1AWV A;  2MS4 A;  3R49 A;  2OK3 A;  1ZKC A; 
#chains in the Genus database with same CATH topology
 2RMA A;  1YND A;  1CWF A;  1DYW A;  2IGV A;  4J59 A;  1ZKF A;  2POY A;  1MIK A;  3CYH A;  1CYN A;  4FRV A;  4YUH A;  5KV5 A;  1CWB A;  1NMK A;  2X2A A;  3R57 A;  3BKP A;  2XGY B;  1BCK A;  3BT8 A;  4LQW A;  2POE A;  2X83 B;  3R4G A;  5DUD A;  3RCL A;  1QNG A;  3RDC A;  3OPF A;  5CCR A;  2MC9 A;  2GW2 A;  1CWA A;  1MF8 C;  4YUJ A;  2CK1 A;  3BO7 A;  4DGB A;  1M9E A;  2NNZ A;  2WFJ A;  3UCH A;  1OCA A;  4J5C X;  4XNC A;  4HY7 A;  3RCK X;  4DGC A;  4J5D X;  5KV3 A;  4O8I A;  4J5B A;  3K0N A;  2ESL A;  5KV7 A;  3T1U A;  3K0Q A;  5KUW A;  3OEP A;  1CWH A;  3K0R A;  5KUR A;  4J5A X;  4TOT A;  1E8K A;  4N1R A;  4FRU A;  1XYH A;  5KUQ A;  1H0P A;  3RCG A;  4N1N A;  1Z81 A;  1CWC A;  1XQ7 A;  2X7K A;  4R3F A;  2RS4 A;  3RCI X;  1XO7 A;  5KUZ A;  4N1S A;  3ICH A;  1AK4 A;  1W74 A;  1AWR A;  4JCP A;  4ZSC A;  1AWQ A;  3R54 A;  2BIU X;  2X2C K;  3K0M A;  4DGD A;  4YUO A;  4YUI A;  4IPZ A;  2FU0 A;  3MML B;  4O8H A;  1VAI A;  4S1E A;  1W8M A;  5KUN A;  1AWT A;  2ALF A;  3PMP A;  3RDD A;  2WLW A;  5CBT A;  3JB9 d;  3RDA X;  4YUP A;  1AWS A;  2BIT X;  2HQ6 A;  2X2D B;  4N1Q A;  4DGE A;  5KUL A;  2K7N A;  5KV1 A;  5KV6 A;  1VDN A;  5KV2 A;  4CYH A;  4DGA A;  1E3B A;  5CBW A;  2X25 B;  2C3B A;  5F66 A;  1V9T A;  1MZW A;  2CFE A;  1IHG A;  5KUO A;  2B71 A;  2IGW A;  2R99 A;  4N1P A;  1CWI A;  2PHC B;  3MML A;  4R3E A;  4S1J A;  1CWK A;  4YUK A;  5CCN A;  5CCQ A;  5JHE A;  1M9Y A;  1CWM A;  1A33 A;  5KUU A;  2MVZ A;  1W8L A;  1AWU A;  3KOP A;  2CMT A;  1QNH A;  2HAQ A;  1M9X A;  4N1O A;  5CCS X;  3O7T A;  2RMC A;  1C5F A;  4J58 A;  4ZSD A;  2HQJ A;  3RDB A;  5KV4 A;  4JJM A;  4EYV A;  1LOP A;  2A2N A;  2PLU A;  3S6M A;  1M9D A;  3RCF A;  2P0O A;  3ODI A;  1M9C A;  1QOI A;  2RMB A;  3K0O A;  3K2C A;  3ORE A;  1VBT A;  2CPL A;  5CYH A;  1CWL A;  1ZMF A;  1XWN A;  2Z6W A;  1VBS A;  1X7F A;  2WFI A;  1A58 A;  1M63 C;  2MZU A;  3ICI A;  5CBV A;  4N1M A;  1J2A A;  5KUS A;  5CBU A;  1RMH A;  2CYH A;  3R56 A;  5KUV A;  4YUG A;  3VA7 A;  2OSE A;  1ZX8 A;  1W8V A;  1IST A;  2OJU A;  2ZP2 A;  4YUL A;  5LUD A;  4YUM A;  4E1Q A;  2N0T A;  3CYS A;  5A0E A;  1CWJ A;  5KV0 A;  3RD9 X;  2NUL A;  1M9F A;  3ODL A;  3RFY A;  1FGL A;  4J5E X;  2QER A;  3K0P A;  1CLH A;  3X27 A;  3R59 A;  1CWO A;  2KA0 A;  3QYU A;  2HE9 A;  4YUN A;  4I9Y A;  1IIP A;  3EOV A;  1AWV A;  2MS4 A;  3R49 A;  2OK3 A;  1ZKC A; 
#chains in the Genus database with same CATH homology
 2RMA A;  1YND A;  1CWF A;  1DYW A;  2IGV A;  4J59 A;  1ZKF A;  2POY A;  1MIK A;  3CYH A;  1CYN A;  4FRV A;  4YUH A;  5KV5 A;  1CWB A;  1NMK A;  2X2A A;  3R57 A;  3BKP A;  2XGY B;  1BCK A;  3BT8 A;  4LQW A;  2POE A;  2X83 B;  3R4G A;  5DUD A;  3RCL A;  1QNG A;  3RDC A;  3OPF A;  5CCR A;  2MC9 A;  2GW2 A;  1CWA A;  1MF8 C;  4YUJ A;  2CK1 A;  3BO7 A;  4DGB A;  1M9E A;  2WFJ A;  3JB9 d;  3UCH A;  1OCA A;  4J5C X;  4XNC A;  4HY7 A;  3RCK X;  4DGC A;  4J5D X;  5KV3 A;  4O8I A;  4J5B A;  3K0N A;  2ESL A;  5KV7 A;  3T1U A;  3K0Q A;  5KUW A;  3OEP A;  1CWH A;  3K0R A;  5KUR A;  4J5A X;  4TOT A;  1E8K A;  4N1R A;  4FRU A;  1XYH A;  5KUQ A;  1H0P A;  3RCG A;  4N1N A;  1Z81 A;  1CWC A;  1XQ7 A;  2X7K A;  4R3F A;  2RS4 A;  3RCI X;  1XO7 A;  5KUZ A;  4N1S A;  3ICH A;  1AK4 A;  1W74 A;  1AWR A;  4JCP A;  4ZSC A;  1AWQ A;  3R54 A;  2BIU X;  2X2C K;  3K0M A;  4DGD A;  4YUO A;  4YUI A;  4IPZ A;  2FU0 A;  3MML B;  4O8H A;  1VAI A;  4S1E A;  1W8M A;  5KUN A;  1AWT A;  2ALF A;  3PMP A;  3RDD A;  2WLW A;  5CBT A;  3RDA X;  4YUP A;  1AWS A;  2BIT X;  2HQ6 A;  2X2D B;  4N1Q A;  4DGE A;  5KUL A;  2K7N A;  5KV1 A;  5KV6 A;  1VDN A;  5KV2 A;  4CYH A;  4DGA A;  1E3B A;  5CBW A;  2X25 B;  2C3B A;  5F66 A;  1V9T A;  1MZW A;  2CFE A;  1IHG A;  5KUO A;  2B71 A;  2IGW A;  2R99 A;  4N1P A;  1CWI A;  2PHC B;  3MML A;  4R3E A;  4S1J A;  1CWK A;  4YUK A;  5CCN A;  5CCQ A;  5JHE A;  1M9Y A;  1CWM A;  1A33 A;  5KUU A;  2MVZ A;  1W8L A;  1AWU A;  2CMT A;  1QNH A;  2HAQ A;  1M9X A;  4N1O A;  5CCS X;  3O7T A;  2RMC A;  1C5F A;  4J58 A;  4ZSD A;  2HQJ A;  3RDB A;  5KV4 A;  4JJM A;  4EYV A;  1LOP A;  2A2N A;  2PLU A;  3S6M A;  1M9D A;  3RCF A;  2P0O A;  3ODI A;  1M9C A;  1QOI A;  2RMB A;  3K0O A;  3K2C A;  3ORE A;  1VBT A;  2CPL A;  5CYH A;  1CWL A;  1ZMF A;  1XWN A;  2Z6W A;  1VBS A;  1X7F A;  2WFI A;  1A58 A;  1M63 C;  2MZU A;  3ICI A;  5CBV A;  4N1M A;  1J2A A;  5KUS A;  5CBU A;  1RMH A;  2CYH A;  3R56 A;  5KUV A;  4YUG A;  3VA7 A;  2OSE A;  1W8V A;  1IST A;  2OJU A;  2ZP2 A;  4YUL A;  5LUD A;  4YUM A;  4E1Q A;  2N0T A;  3CYS A;  5A0E A;  1CWJ A;  5KV0 A;  3RD9 X;  2NUL A;  1M9F A;  3ODL A;  3RFY A;  1FGL A;  4J5E X;  2QER A;  3K0P A;  1CLH A;  3R59 A;  1CWO A;  3QYU A;  2HE9 A;  4YUN A;  4I9Y A;  1IIP A;  3EOV A;  1AWV A;  2MS4 A;  3R49 A;  2OK3 A;  1ZKC A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

5KUQA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations