|
27
|
84
|
4zycA |
Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-mdm2 interaction with a distinct binding mode: hdm2 (mdm2) complexed with cpd5 |
|
29
|
83
|
5afgA |
Structure of the stapled peptide bound to mdm2 |
|
31
|
95
|
4zfiA |
Structure of mdm2 with low molecular weight inhibitor |
|
34
|
94
|
4zgkA |
Structure of mdm2 with low molecular weight inhibitor. |
|
31
|
93
|
4zyfA |
Discovery of nvp-cgm097 - a highly potent and selective mdm2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: hdm2 (mdm2) complexed with nvp-cgm097 |
|
54
|
155
|
4zlcA |
Crystal structure of the roq domain of human roquin-2 |
|
30
|
91
|
4zyiA |
Discovery of nvp-cgm097 - a highly potent and selective mdm2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: hdm2 (mdm2) complexed with cpd2 |
|
52
|
183
|
4ybmA |
Crystal structure of trim24 phd-bromodomain complexed with n-{6-[3-(benzyloxy)phenoxy]-1,3-dimethyl-2-oxo-2,3-dihydro-1h-1,3-benzodiazol-5-yl}-3,4-dimethoxybenzene-1-sulfonamide (7b) |
|
57
|
183
|
4ybsA |
Crystal structure of trim24 phd-bromodomain complexed with n-{1,3-dimethyl-6-[3-(2-methylpropoxy)phenoxy]-2-oxo-2,3-dihydro-1h-1,3-benzodiazol-5-yl}-1,2-dimethyl-1h-imidazole-4-sulfonamide (7g) |
|
50
|
152
|
4ywqA |
Crystal structure of the roq domain of human roquin-1 |
|
18
|
78
|
4tkpB |
Complex of ubc13 with the ring domain of the trim5alpha retroviral restriction factor |
|
54
|
184
|
4yabA |
Crystal structure of trim24 phd-bromodomain complexed with 1-methyl-5-(2-methyl-1 3-thiazol-4-yl)-2 3-dihydro-1h-indol-2-one (1) |
|
25
|
90
|
4ereA |
Crystal structure of mdm2 (17-111) in complex with compound 23 |
|
26
|
92
|
4qocA |
Crystal structure of compound 16 bound to mdm2(17-111), {(3r,5r,6s)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(1s)-1-cyclopropyl-2-(pyrrolidin-1-ylsulfonyl)ethyl]-3-methyl-2-oxopiperidin-3-yl}acetic acid |
|
11
|
85
|
4f52B |
Structure of a glomulin-rbx1-cul1 complex |
|
32
|
109
|
4ec4A |
Xiap-bir3 in complex with a potent divalent smac mimetic |
|
27
|
92
|
4erfA |
Crystal structure of mdm2 (17-111) in complex with compound 29 (am-8553) |
|
18
|
102
|
4eb9A |
Ciap1-bir3 in complex with a divalent smac mimetic |
|
33
|
93
|
4dijA |
The central valine concept provides an entry in a new class of non peptide inhibitors of the p53-mdm2 interaction |
|
10
|
75
|
4ccgX |
Structure of an e2-e3 complex |
|
40
|
152
|
4c86A |
Mouse znrf3 ectodomain crystal form i |
|
37
|
151
|
4c84A |
Zebrafish znrf3 ectodomain crystal form i |
|
40
|
153
|
4cdjA |
Structure of znrf3 ectodomain |
|
43
|
193
|
4c9zA |
Crystal structure of siah1 at 1.95 a resolution |
|
69
|
164
|
4cfgA |
Structure of the trim25 coiled-coil |
|
33
|
153
|
4c8aA |
Mouse znrf3 ectodomain crystal form ii |
|
35
|
153
|
4c99A |
Mouse znrf3 ectodomain in complex with mouse rspo2 fu1-fu2 crystal form i |
|
37
|
153
|
4c9eA |
Mouse znrf3 ectodomain in complex with xenopus rspo2 fu1-fu2 (seleno met) crystal form ii |
|
38
|
161
|
4c9rA |
Xenopus znrf3 ectodomain in complex with xenopus rspo2 fu1-fu2 crystal form i |
|
33
|
152
|
4c8tA |
Xenopus znrf3 ectodomain crystal form i |
|
40
|
152
|
4cdkA |
Structure of znrf3-rspo1 |
|
38
|
151
|
4c8pA |
Mouse znrf3 ectodomain crystal form v, disulfide-bridged s90c variant |
|
39
|
161
|
4c9uA |
Xenopus znrf3 ectodomain in complex with xenopus rspo2 fu1-fu2 crystal form ii |
|
32
|
151
|
4c8fA |
Mouse znrf3 ectodomain crystal form iv |
|
42
|
192
|
4ca1A |
Crystal structure of siah1 at 1.58 a resolution. |
|
37
|
151
|
4c8cA |
Mouse znrf3 ectodomain crystal form iii |
|
36
|
151
|
4c85A |
Zebrafish znrf3 ectodomain crystal form ii |
|
33
|
152
|
4c8uA |
Xenopus znrf3 ectodomain crystal form ii |
|
38
|
153
|
4c9aA |
Mouse znrf3 ectodomain in complex with xenopus rspo2 fu1-fu2 (seleno met) crystal form i |
|
159
|
584
|
4b3nA |
Crystal structure of rhesus trim5alpha pry/spry domain |
|
11
|
57
|
4auqB |
Structure of birc7-ubch5b-ub complex. |
|
30
|
129
|
4ap4A |
Rnf4 - ubch5a - ubiquitin heterotrimeric complex |
|
48
|
136
|
4aycA |
Rnf8 ring domain structure |
|
42
|
127
|
4aycB |
Rnf8 ring domain structure |
|
52
|
194
|
4b8eA |
Pry-spry domain of trim25 |
|
11
|
65
|
3zvyA |
Phd finger of human uhrf1 in complex with unmodified histone h3 n- terminal tail |
|
8
|
89
|
4a0cD |
Structure of the cand1-cul4b-rbx1 complex |
|
123
|
388
|
4a4bA |
Structure of modified phosphotyr371-c-cbl-ubch5b-zap-70 complex |
|
46
|
180
|
3zo0B |
Mouse igg2a in complex with mouse trim21 pryspry |
|
20
|
77
|
4a49A |
Structure of phosphotyr371-c-cbl-ubch5b complex |
