1AM4A

Complex between cdc42hs.gmppnp and p50 rhogap (h. sapiens)
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
199
structure length
199
Chain Sequence
PRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP.
pubmed doi rcsb
molecule keywords P50-RHOGAP
molecule tags Complex (gtpase-activating/gtp-binding)
source organism Homo sapiens
total genus 48
structure length 199
sequence length 199
chains with identical sequence B, C
ec nomenclature
pdb deposition date 1997-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1am4A00
1AM4A 1OW3A 1RGPA 3WPSA 1TX4A 3IUGA 5JD0A 1PBWA 2OVJA 3KUQA 2EE4A 1F7CA 3MSXB 2OSAA 2XS6A 3FK2A 2NGRB 5C2JA 3CXLA 3QISA 5JCPA 1XA6A 2EE5A 3WPQA 1GRNB 2QV2A 3BYIA 5IRCA 5C5SA 5HPYA 3W6RA 2MBGA 3EAPA
chains in the Genus database with same CATH superfamily
1AM4A 1OW3A 1RGPA 3WPSA 1TX4A 3IUGA 5JD0A 1PBWA 2OVJA 3KUQA 2EE4A 1F7CA 3MSXB 2OSAA 2XS6A 3FK2A 2NGRB 5C2JA 3CXLA 3QISA 5JCPA 1XA6A 2EE5A 3WPQA 1GRNB 2QV2A 3BYIA 5IRCA 5C5SA 5HPYA 3W6RA 2MBGA 3EAPA
chains in the Genus database with same CATH topology
1AM4A 1OW3A 1RGPA 3WPSA 1TX4A 3IUGA 5JD0A 1PBWA 2OVJA 3KUQA 2EE4A 1F7CA 3MSXB 2OSAA 2XS6A 3FK2A 2NGRB 5C2JA 3CXLA 3QISA 5JCPA 1XA6A 2EE5A 3WPQA 1GRNB 2QV2A 3BYIA 5IRCA 5C5SA 5HPYA 3W6RA 2MBGA 3EAPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AM4 A;  1OW3 A;  1RGP A;  3WPS A;  1TX4 A;  3IUG A;  5JD0 A;  1PBW A;  2OVJ A;  3KUQ A;  2EE4 A;  1F7C A;  3MSX B;  2OSA A;  2XS6 A;  3FK2 A;  2NGR B;  5C2J A;  3CXL A;  3QIS A;  5JCP A;  1XA6 A;  2EE5 A;  3WPQ A;  1GRN B;  2QV2 A;  3BYI A;  5IRC A;  5C5S A;  5HPY A;  3W6R A;  2MBG A;  3EAP A; 
#chains in the Genus database with same CATH topology
 1AM4 A;  1OW3 A;  1RGP A;  3WPS A;  1TX4 A;  3IUG A;  5JD0 A;  1PBW A;  2OVJ A;  3KUQ A;  2EE4 A;  1F7C A;  3MSX B;  2OSA A;  2XS6 A;  3FK2 A;  2NGR B;  5C2J A;  3CXL A;  3QIS A;  5JCP A;  1XA6 A;  2EE5 A;  3WPQ A;  1GRN B;  2QV2 A;  3BYI A;  5IRC A;  5C5S A;  5HPY A;  3W6R A;  2MBG A;  3EAP A; 
#chains in the Genus database with same CATH homology
 1AM4 A;  1OW3 A;  1RGP A;  3WPS A;  1TX4 A;  3IUG A;  5JD0 A;  1PBW A;  2OVJ A;  3KUQ A;  2EE4 A;  1F7C A;  3MSX B;  2OSA A;  2XS6 A;  3FK2 A;  2NGR B;  5C2J A;  3CXL A;  3QIS A;  5JCP A;  1XA6 A;  2EE5 A;  3WPQ A;  1GRN B;  2QV2 A;  3BYI A;  5IRC A;  5C5S A;  5HPY A;  3W6R A;  2MBG A;  3EAP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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