1AM4A

Complex between cdc42hs.gmppnp and p50 rhogap (h. sapiens)
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
199
structure length
199
Chain Sequence
PRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP.
pubmed doi rcsb
molecule tags Complex (gtpase-activating/gtp-binding)
source organism Homo sapiens
molecule keywords P50-RHOGAP
total genus 48
structure length 199
sequence length 199
chains with identical sequence B, C
ec nomenclature
pdb deposition date 1997-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1am4A00
5IRCA 1XA6A 5C2JA 5JCPA 1F7CA 3KUQA 5HPYA 3IUGA 3W6RA 1GRNB 3MSXB 3BYIA 2XS6A 3CXLA 2OSAA 1PBWA 1OW3A 1AM4A 2OVJA 3EAPA 2MBGA 5C5SA 5JD0A 2QV2A 3WPQA 2EE4A 2EE5A 2NGRB 3WPSA 3QISA 1TX4A 3FK2A 1RGPA
chains in the Genus database with same CATH superfamily
5IRCA 1XA6A 5C2JA 5JCPA 1F7CA 3KUQA 5HPYA 3IUGA 3W6RA 1GRNB 3MSXB 3BYIA 2XS6A 3CXLA 2OSAA 1PBWA 1OW3A 1AM4A 2OVJA 3EAPA 2MBGA 5C5SA 5JD0A 2QV2A 3WPQA 2EE4A 2EE5A 2NGRB 3WPSA 3QISA 1TX4A 3FK2A 1RGPA
chains in the Genus database with same CATH topology
5IRCA 1XA6A 5C2JA 5JCPA 1F7CA 3KUQA 5HPYA 3IUGA 3W6RA 1GRNB 3MSXB 3BYIA 2XS6A 3CXLA 2OSAA 1PBWA 1OW3A 1AM4A 2OVJA 3EAPA 2MBGA 5C5SA 5JD0A 2QV2A 3WPQA 2EE4A 2EE5A 2NGRB 3WPSA 3QISA 1TX4A 3FK2A 1RGPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IRC A;  1XA6 A;  5C2J A;  5JCP A;  1F7C A;  3KUQ A;  5HPY A;  3IUG A;  3W6R A;  1GRN B;  3MSX B;  3BYI A;  2XS6 A;  3CXL A;  2OSA A;  1PBW A;  1OW3 A;  1AM4 A;  2OVJ A;  3EAP A;  2MBG A;  5C5S A;  5JD0 A;  2QV2 A;  3WPQ A;  2EE4 A;  2EE5 A;  2NGR B;  3WPS A;  3QIS A;  1TX4 A;  3FK2 A;  1RGP A; 
#chains in the Genus database with same CATH topology
 5IRC A;  1XA6 A;  5C2J A;  5JCP A;  1F7C A;  3KUQ A;  5HPY A;  3IUG A;  3W6R A;  1GRN B;  3MSX B;  3BYI A;  2XS6 A;  3CXL A;  2OSA A;  1PBW A;  1OW3 A;  1AM4 A;  2OVJ A;  3EAP A;  2MBG A;  5C5S A;  5JD0 A;  2QV2 A;  3WPQ A;  2EE4 A;  2EE5 A;  2NGR B;  3WPS A;  3QIS A;  1TX4 A;  3FK2 A;  1RGP A; 
#chains in the Genus database with same CATH homology
 5IRC A;  1XA6 A;  5C2J A;  5JCP A;  1F7C A;  3KUQ A;  5HPY A;  3IUG A;  3W6R A;  1GRN B;  3MSX B;  3BYI A;  2XS6 A;  3CXL A;  2OSA A;  1PBW A;  1OW3 A;  1AM4 A;  2OVJ A;  3EAP A;  2MBG A;  5C5S A;  5JD0 A;  2QV2 A;  3WPQ A;  2EE4 A;  2EE5 A;  2NGR B;  3WPS A;  3QIS A;  1TX4 A;  3FK2 A;  1RGP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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