1AM4 | Genus

Total Genus 48

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	48
sequence length	199
structure length	199
Chain Sequence	PRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 199 atoms

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199 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP. pubmed doi rcsb
molecule keywords	P50-RHOGAP
molecule tags	Complex (gtpase-activating/gtp-binding)
source organism	Homo sapiens
total genus	48
structure length	199
sequence length	199
chains with identical sequence	B, C
ec nomenclature
pdb deposition date	1997-06-22

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00620	RhoGAP	RhoGAP domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.555.10	Mainly Alpha	Orthogonal Bundle	Phosphatidylinositol 3-kinase; Chain A	Rho GTPase activation protein	1am4A00

5C5SA 5HPYA 3IUGA 1TX4A 5C2JA 3WPQA 3MSXB 3EAPA 1GRNB 2EE5A 1F7CA 2NGRB 1RGPA 3BYIA 3FK2A 2XS6A 3W6RA 3WPSA 1AM4A 5IRCA 1PBWA 2QV2A 3QISA 2EE4A 2OVJA 2MBGA 3CXLA 1XA6A 1OW3A 5JCPA 5JD0A 3KUQA 2OSAA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5C5S A;  5HPY A;  3IUG A;  1TX4 A;  5C2J A;  3WPQ A;  3MSX B;  3EAP A;  1GRN B;  2EE5 A;  1F7C A;  2NGR B;  1RGP A;  3BYI A;  3FK2 A;  2XS6 A;  3W6R A;  3WPS A;  1AM4 A;  5IRC A;  1PBW A;  2QV2 A;  3QIS A;  2EE4 A;  2OVJ A;  2MBG A;  3CXL A;  1XA6 A;  1OW3 A;  5JCP A;  5JD0 A;  3KUQ A;  2OSA A; 
#chains in the Genus database with same CATH topology
 5C5S A;  5HPY A;  3IUG A;  1TX4 A;  5C2J A;  3WPQ A;  3MSX B;  3EAP A;  1GRN B;  2EE5 A;  1F7C A;  2NGR B;  1RGP A;  3BYI A;  3FK2 A;  2XS6 A;  3W6R A;  3WPS A;  1AM4 A;  5IRC A;  1PBW A;  2QV2 A;  3QIS A;  2EE4 A;  2OVJ A;  2MBG A;  3CXL A;  1XA6 A;  1OW3 A;  5JCP A;  5JD0 A;  3KUQ A;  2OSA A; 
#chains in the Genus database with same CATH homology
 5C5S A;  5HPY A;  3IUG A;  1TX4 A;  5C2J A;  3WPQ A;  3MSX B;  3EAP A;  1GRN B;  2EE5 A;  1F7C A;  2NGR B;  1RGP A;  3BYI A;  3FK2 A;  2XS6 A;  3W6R A;  3WPS A;  1AM4 A;  5IRC A;  1PBW A;  2QV2 A;  3QIS A;  2EE4 A;  2OVJ A;  2MBG A;  3CXL A;  1XA6 A;  1OW3 A;  5JCP A;  5JD0 A;  3KUQ A;  2OSA A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1AM4A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations