1AM4A

Complex between cdc42hs.gmppnp and p50 rhogap (h. sapiens)
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
199
structure length
199
Chain Sequence
PRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Complex (gtpase-activating/gtp-binding)
molecule keywords P50-RHOGAP
publication title Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP.
pubmed doi rcsb
source organism Homo sapiens
total genus 48
structure length 199
sequence length 199
chains with identical sequence B, C
ec nomenclature
pdb deposition date 1997-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1am4A00
5C5SA 3FK2A 1XA6A 1F7CA 3WPQA 2MBGA 2OVJA 3BYIA 3WPSA 1GRNB 2XS6A 5HPYA 1AM4A 2OSAA 1PBWA 3IUGA 5JD0A 2EE5A 1RGPA 2NGRB 5JCPA 5IRCA 3MSXB 3KUQA 3W6RA 2EE4A 3QISA 1OW3A 3CXLA 5C2JA 2QV2A 3EAPA 1TX4A
chains in the Genus database with same CATH superfamily
5C5SA 3FK2A 1XA6A 1F7CA 3WPQA 2MBGA 2OVJA 3BYIA 3WPSA 1GRNB 2XS6A 5HPYA 1AM4A 2OSAA 1PBWA 3IUGA 5JD0A 2EE5A 1RGPA 2NGRB 5JCPA 5IRCA 3MSXB 3KUQA 3W6RA 2EE4A 3QISA 1OW3A 3CXLA 5C2JA 2QV2A 3EAPA 1TX4A
chains in the Genus database with same CATH topology
5C5SA 3FK2A 1XA6A 1F7CA 3WPQA 2MBGA 2OVJA 3BYIA 3WPSA 1GRNB 2XS6A 5HPYA 1AM4A 2OSAA 1PBWA 3IUGA 5JD0A 2EE5A 1RGPA 2NGRB 5JCPA 5IRCA 3MSXB 3KUQA 3W6RA 2EE4A 3QISA 1OW3A 3CXLA 5C2JA 2QV2A 3EAPA 1TX4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C5S A;  3FK2 A;  1XA6 A;  1F7C A;  3WPQ A;  2MBG A;  2OVJ A;  3BYI A;  3WPS A;  1GRN B;  2XS6 A;  5HPY A;  1AM4 A;  2OSA A;  1PBW A;  3IUG A;  5JD0 A;  2EE5 A;  1RGP A;  2NGR B;  5JCP A;  5IRC A;  3MSX B;  3KUQ A;  3W6R A;  2EE4 A;  3QIS A;  1OW3 A;  3CXL A;  5C2J A;  2QV2 A;  3EAP A;  1TX4 A; 
#chains in the Genus database with same CATH topology
 5C5S A;  3FK2 A;  1XA6 A;  1F7C A;  3WPQ A;  2MBG A;  2OVJ A;  3BYI A;  3WPS A;  1GRN B;  2XS6 A;  5HPY A;  1AM4 A;  2OSA A;  1PBW A;  3IUG A;  5JD0 A;  2EE5 A;  1RGP A;  2NGR B;  5JCP A;  5IRC A;  3MSX B;  3KUQ A;  3W6R A;  2EE4 A;  3QIS A;  1OW3 A;  3CXL A;  5C2J A;  2QV2 A;  3EAP A;  1TX4 A; 
#chains in the Genus database with same CATH homology
 5C5S A;  3FK2 A;  1XA6 A;  1F7C A;  3WPQ A;  2MBG A;  2OVJ A;  3BYI A;  3WPS A;  1GRN B;  2XS6 A;  5HPY A;  1AM4 A;  2OSA A;  1PBW A;  3IUG A;  5JD0 A;  2EE5 A;  1RGP A;  2NGR B;  5JCP A;  5IRC A;  3MSX B;  3KUQ A;  3W6R A;  2EE4 A;  3QIS A;  1OW3 A;  3CXL A;  5C2J A;  2QV2 A;  3EAP A;  1TX4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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