1AT0A

17-kda fragment of hedgehog c-terminal autoprocessing domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
145
structure length
145
Chain Sequence
CFTPESTALLESGVRKPLGELSIGDRVLSMTANGQAVYSEVILFMDRNLEQMQNFVQLHTDGGAVLTVTPAHLVSVWQPESQKLTFVFADRIEEKNQVLVRDVETGELRPQRVVKVGSVRSKGVVAPLTREGTIVVNSVAASCYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins.
pubmed doi rcsb
molecule tags Signaling protein
source organism Drosophila melanogaster
molecule keywords 17-HEDGEHOG
total genus 29
structure length 145
sequence length 145
ec nomenclature
pdb deposition date 1997-08-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.16.10 Mainly Beta Beta Complex Endonuclease - Pi-scei; Chain A, domain 1 Hedgehog/Intein (Hint) domain 1at0A00
1EF0A 1ZDEA 5K08A 2LQMA 2LWYA 2CW7A 2CW8A 1GPPA 4O1SA 2LCJA 5I0AA 4KL6A 4KL5A 1ZD7A 4GIGA 1LWSA 1AT0A 4E2TA 2L8LA 2JNQA 1AM2A 2IN9A 2IMZA 2IN8A 2JMZA 4E2UA 3IGDA 3NZMA 4OZ6A 2IN0A 1VDEA 1DFAA 4O1RA 1DQ3A 2KEQA 3IFJA 1MI8A 1JVAA 1LWTA 1UM2A
chains in the Genus database with same CATH superfamily
1EF0A 1ZDEA 5K08A 4QFQA 2LQMA 2LWYA 2CW7A 2CW8A 1GPPA 4O1SA 2LCJA 5I0AA 4KL6A 4KL5A 1ZD7A 4GIGA 4LX3A 1AT0A 4E2TA 1LWSA 2L8LA 2JNQA 1AM2A 2IN9A 2IMZA 2IN8A 2JMZA 4E2UA 3IGDA 3NZMA 4OZ6A 2IN0A 1VDEA 1DFAA 4O1RA 1DQ3A 2KEQA 3IFJA 1MI8A 1JVAA 1LWTA 1UM2A
chains in the Genus database with same CATH topology
1EF0A 1ZDEA 5K08A 2LQMA 2LWYA 2CW7A 2CW8A 1GPPA 4O1SA 2LCJA 5I0AA 4KL6A 4KL5A 1ZD7A 4GIGA 1LWSA 1AT0A 4E2TA 2L8LA 2JNQA 1AM2A 2IN9A 2IMZA 2IN8A 2JMZA 4E2UA 3IGDA 3NZMA 4OZ6A 2IN0A 1VDEA 1DFAA 4O1RA 1DQ3A 2KEQA 3IFJA 1MI8A 1JVAA 1LWTA 1UM2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EF0 A;  1ZDE A;  5K08 A;  2LQM A;  2LWY A;  2CW7 A;  2CW8 A;  1GPP A;  4O1S A;  2LCJ A;  5I0A A;  4KL6 A;  4KL5 A;  1ZD7 A;  4GIG A;  1LWS A;  1AT0 A;  4E2T A;  2L8L A;  2JNQ A;  1AM2 A;  2IN9 A;  2IMZ A;  2IN8 A;  2JMZ A;  4E2U A;  3IGD A;  3NZM A;  4OZ6 A;  2IN0 A;  1VDE A;  1DFA A;  4O1R A;  1DQ3 A;  2KEQ A;  3IFJ A;  1MI8 A;  1JVA A;  1LWT A;  1UM2 A; 
#chains in the Genus database with same CATH topology
 1EF0 A;  1ZDE A;  5K08 A;  4QFQ A;  2LQM A;  2LWY A;  2CW7 A;  2CW8 A;  1GPP A;  4O1S A;  2LCJ A;  5I0A A;  4KL6 A;  4KL5 A;  1ZD7 A;  4GIG A;  4LX3 A;  1AT0 A;  4E2T A;  1LWS A;  2L8L A;  2JNQ A;  1AM2 A;  2IN9 A;  2IMZ A;  2IN8 A;  2JMZ A;  4E2U A;  3IGD A;  3NZM A;  4OZ6 A;  2IN0 A;  1VDE A;  1DFA A;  4O1R A;  1DQ3 A;  2KEQ A;  3IFJ A;  1MI8 A;  1JVA A;  1LWT A;  1UM2 A; 
#chains in the Genus database with same CATH homology
 1EF0 A;  1ZDE A;  5K08 A;  2LQM A;  2LWY A;  2CW7 A;  2CW8 A;  1GPP A;  4O1S A;  2LCJ A;  5I0A A;  4KL6 A;  4KL5 A;  1ZD7 A;  4GIG A;  1LWS A;  1AT0 A;  4E2T A;  2L8L A;  2JNQ A;  1AM2 A;  2IN9 A;  2IMZ A;  2IN8 A;  2JMZ A;  4E2U A;  3IGD A;  3NZM A;  4OZ6 A;  2IN0 A;  1VDE A;  1DFA A;  4O1R A;  1DQ3 A;  2KEQ A;  3IFJ A;  1MI8 A;  1JVA A;  1LWT A;  1UM2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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