1AT0A

17-kda fragment of hedgehog c-terminal autoprocessing domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
145
structure length
145
Chain Sequence
CFTPESTALLESGVRKPLGELSIGDRVLSMTANGQAVYSEVILFMDRNLEQMQNFVQLHTDGGAVLTVTPAHLVSVWQPESQKLTFVFADRIEEKNQVLVRDVETGELRPQRVVKVGSVRSKGVVAPLTREGTIVVNSVAASCYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins.
pubmed doi rcsb
molecule tags Signaling protein
source organism Drosophila melanogaster
molecule keywords 17-HEDGEHOG
total genus 29
structure length 145
sequence length 145
ec nomenclature
pdb deposition date 1997-08-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.16.10 Mainly Beta Beta Complex Endonuclease - Pi-scei; Chain A, domain 1 Hedgehog/Intein (Hint) domain 1at0A00
3IFJA 5I0AA 4GIGA 1LWTA 2JMZA 2CW7A 4O1RA 1EF0A 4OZ6A 3IGDA 1LWSA 1DFAA 1MI8A 4KL5A 2IN8A 1AM2A 4E2UA 1JVAA 2JNQA 5K08A 2CW8A 1DQ3A 2KEQA 2LCJA 4E2TA 4O1SA 1VDEA 2IN0A 1ZD7A 2L8LA 2LQMA 3NZMA 1ZDEA 1AT0A 2LWYA 1UM2A 2IMZA 4KL6A 1GPPA 2IN9A
chains in the Genus database with same CATH superfamily
3IFJA 5I0AA 4GIGA 1LWTA 2JMZA 2CW7A 4O1RA 1EF0A 4OZ6A 3IGDA 1LWSA 1DFAA 1MI8A 4KL5A 2IN8A 1AM2A 4E2UA 1JVAA 4LX3A 2JNQA 5K08A 2CW8A 1DQ3A 2KEQA 2LCJA 4E2TA 4O1SA 1VDEA 2IN0A 1ZD7A 2L8LA 2LQMA 3NZMA 1ZDEA 1AT0A 2LWYA 1UM2A 2IMZA 4KL6A 4QFQA 1GPPA 2IN9A
chains in the Genus database with same CATH topology
3IFJA 5I0AA 4GIGA 1LWTA 2JMZA 2CW7A 4O1RA 1EF0A 4OZ6A 3IGDA 1LWSA 1DFAA 1MI8A 4KL5A 2IN8A 1AM2A 4E2UA 1JVAA 2JNQA 5K08A 2CW8A 1DQ3A 2KEQA 2LCJA 4E2TA 4O1SA 1VDEA 2IN0A 1ZD7A 2L8LA 2LQMA 3NZMA 1ZDEA 1AT0A 2LWYA 1UM2A 2IMZA 4KL6A 1GPPA 2IN9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IFJ A;  5I0A A;  4GIG A;  1LWT A;  2JMZ A;  2CW7 A;  4O1R A;  1EF0 A;  4OZ6 A;  3IGD A;  1LWS A;  1DFA A;  1MI8 A;  4KL5 A;  2IN8 A;  1AM2 A;  4E2U A;  1JVA A;  2JNQ A;  5K08 A;  2CW8 A;  1DQ3 A;  2KEQ A;  2LCJ A;  4E2T A;  4O1S A;  1VDE A;  2IN0 A;  1ZD7 A;  2L8L A;  2LQM A;  3NZM A;  1ZDE A;  1AT0 A;  2LWY A;  1UM2 A;  2IMZ A;  4KL6 A;  1GPP A;  2IN9 A; 
#chains in the Genus database with same CATH topology
 3IFJ A;  5I0A A;  4GIG A;  1LWT A;  2JMZ A;  2CW7 A;  4O1R A;  1EF0 A;  4OZ6 A;  3IGD A;  1LWS A;  1DFA A;  1MI8 A;  4KL5 A;  2IN8 A;  1AM2 A;  4E2U A;  1JVA A;  4LX3 A;  2JNQ A;  5K08 A;  2CW8 A;  1DQ3 A;  2KEQ A;  2LCJ A;  4E2T A;  4O1S A;  1VDE A;  2IN0 A;  1ZD7 A;  2L8L A;  2LQM A;  3NZM A;  1ZDE A;  1AT0 A;  2LWY A;  1UM2 A;  2IMZ A;  4KL6 A;  4QFQ A;  1GPP A;  2IN9 A; 
#chains in the Genus database with same CATH homology
 3IFJ A;  5I0A A;  4GIG A;  1LWT A;  2JMZ A;  2CW7 A;  4O1R A;  1EF0 A;  4OZ6 A;  3IGD A;  1LWS A;  1DFA A;  1MI8 A;  4KL5 A;  2IN8 A;  1AM2 A;  4E2U A;  1JVA A;  2JNQ A;  5K08 A;  2CW8 A;  1DQ3 A;  2KEQ A;  2LCJ A;  4E2T A;  4O1S A;  1VDE A;  2IN0 A;  1ZD7 A;  2L8L A;  2LQM A;  3NZM A;  1ZDE A;  1AT0 A;  2LWY A;  1UM2 A;  2IMZ A;  4KL6 A;  1GPP A;  2IN9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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