1F7CA

Crystal structure of the bh domain from graf, the gtpase regulator associated with focal adhesion kinase
Total Genus 64
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
191
structure length
182
Chain Sequence
AQLDSIGFSIIKKCIHAVETRGINEQGLYRIVGVNSRVQKLLSILMDPETEICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLHLLMNHLAKVADNHKQNLMTVANLGVVFGPTLLRPTVAAIMDIKFQNIVIEILIENHEKIFNTVPE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the BH domain from graf and its implications for Rho GTPase recognition.
pubmed doi rcsb
molecule keywords RHOGAP PROTEIN
molecule tags Signaling protein
source organism Gallus gallus
total genus 64
structure length 182
sequence length 191
ec nomenclature
pdb deposition date 2000-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1f7cA00
3WPQA 2OVJA 1AM4A 1OW3A 2XS6A 3EAPA 3KUQA 5JD0A 5C5SA 3CXLA 5C2JA 5JCPA 2NGRB 2OSAA 3QISA 3WPSA 3MSXB 1XA6A 2EE5A 1TX4A 1PBWA 3BYIA 3FK2A 5IRCA 2QV2A 1F7CA 1RGPA 3W6RA 2EE4A 1GRNB 2MBGA 5HPYA 3IUGA
chains in the Genus database with same CATH superfamily
3WPQA 2OVJA 1AM4A 1OW3A 2XS6A 3EAPA 3KUQA 5JD0A 5C5SA 3CXLA 5C2JA 5JCPA 2NGRB 2OSAA 3QISA 3WPSA 3MSXB 1XA6A 2EE5A 1TX4A 1PBWA 3BYIA 3FK2A 5IRCA 2QV2A 1F7CA 1RGPA 3W6RA 2EE4A 1GRNB 2MBGA 5HPYA 3IUGA
chains in the Genus database with same CATH topology
3WPQA 2OVJA 1AM4A 1OW3A 2XS6A 3EAPA 3KUQA 5JD0A 5C5SA 3CXLA 5C2JA 5JCPA 2NGRB 2OSAA 3QISA 3WPSA 3MSXB 1XA6A 2EE5A 1TX4A 1PBWA 3BYIA 3FK2A 5IRCA 2QV2A 1F7CA 1RGPA 3W6RA 2EE4A 1GRNB 2MBGA 5HPYA 3IUGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WPQ A;  2OVJ A;  1AM4 A;  1OW3 A;  2XS6 A;  3EAP A;  3KUQ A;  5JD0 A;  5C5S A;  3CXL A;  5C2J A;  5JCP A;  2NGR B;  2OSA A;  3QIS A;  3WPS A;  3MSX B;  1XA6 A;  2EE5 A;  1TX4 A;  1PBW A;  3BYI A;  3FK2 A;  5IRC A;  2QV2 A;  1F7C A;  1RGP A;  3W6R A;  2EE4 A;  1GRN B;  2MBG A;  5HPY A;  3IUG A; 
#chains in the Genus database with same CATH topology
 3WPQ A;  2OVJ A;  1AM4 A;  1OW3 A;  2XS6 A;  3EAP A;  3KUQ A;  5JD0 A;  5C5S A;  3CXL A;  5C2J A;  5JCP A;  2NGR B;  2OSA A;  3QIS A;  3WPS A;  3MSX B;  1XA6 A;  2EE5 A;  1TX4 A;  1PBW A;  3BYI A;  3FK2 A;  5IRC A;  2QV2 A;  1F7C A;  1RGP A;  3W6R A;  2EE4 A;  1GRN B;  2MBG A;  5HPY A;  3IUG A; 
#chains in the Genus database with same CATH homology
 3WPQ A;  2OVJ A;  1AM4 A;  1OW3 A;  2XS6 A;  3EAP A;  3KUQ A;  5JD0 A;  5C5S A;  3CXL A;  5C2J A;  5JCP A;  2NGR B;  2OSA A;  3QIS A;  3WPS A;  3MSX B;  1XA6 A;  2EE5 A;  1TX4 A;  1PBW A;  3BYI A;  3FK2 A;  5IRC A;  2QV2 A;  1F7C A;  1RGP A;  3W6R A;  2EE4 A;  1GRN B;  2MBG A;  5HPY A;  3IUG A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...