1F7CA

Crystal structure of the bh domain from graf, the gtpase regulator associated with focal adhesion kinase
Total Genus 64
204060801001201401600102030405060
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
191
structure length
182
Chain Sequence
AQLDSIGFSIIKKCIHAVETRGINEQGLYRIVGVNSRVQKLLSILMDPETEICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLHLLMNHLAKVADNHKQNLMTVANLGVVFGPTLLRPTVAAIMDIKFQNIVIEILIENHEKIFNTVPE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the BH domain from graf and its implications for Rho GTPase recognition.
pubmed doi rcsb
molecule keywords RHOGAP PROTEIN
molecule tags Signaling protein
source organism Gallus gallus
total genus 64
structure length 182
sequence length 191
ec nomenclature
pdb deposition date 2000-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1f7cA00
3BYIA 5IRCA 1F7CA 3FK2A 1TX4A 3CXLA 3EAPA 2MBGA 5C2JA 1GRNB 1RGPA 2OSAA 3QISA 3MSXB 5JCPA 2OVJA 1XA6A 1PBWA 5JD0A 3WPQA 2EE4A 3KUQA 2QV2A 3IUGA 2XS6A 1AM4A 5C5SA 1OW3A 3WPSA 2NGRB 5HPYA 2EE5A 3W6RA
chains in the Genus database with same CATH superfamily
3BYIA 5IRCA 1F7CA 3FK2A 1TX4A 3CXLA 3EAPA 2MBGA 5C2JA 1GRNB 1RGPA 2OSAA 3QISA 3MSXB 5JCPA 2OVJA 1XA6A 1PBWA 5JD0A 3WPQA 2EE4A 3KUQA 2QV2A 3IUGA 2XS6A 1AM4A 5C5SA 1OW3A 3WPSA 2NGRB 5HPYA 2EE5A 3W6RA
chains in the Genus database with same CATH topology
3BYIA 5IRCA 1F7CA 3FK2A 1TX4A 3CXLA 3EAPA 2MBGA 5C2JA 1GRNB 1RGPA 2OSAA 3QISA 3MSXB 5JCPA 2OVJA 1XA6A 1PBWA 5JD0A 3WPQA 2EE4A 3KUQA 2QV2A 3IUGA 2XS6A 1AM4A 5C5SA 1OW3A 3WPSA 2NGRB 5HPYA 2EE5A 3W6RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BYI A;  5IRC A;  1F7C A;  3FK2 A;  1TX4 A;  3CXL A;  3EAP A;  2MBG A;  5C2J A;  1GRN B;  1RGP A;  2OSA A;  3QIS A;  3MSX B;  5JCP A;  2OVJ A;  1XA6 A;  1PBW A;  5JD0 A;  3WPQ A;  2EE4 A;  3KUQ A;  2QV2 A;  3IUG A;  2XS6 A;  1AM4 A;  5C5S A;  1OW3 A;  3WPS A;  2NGR B;  5HPY A;  2EE5 A;  3W6R A; 
#chains in the Genus database with same CATH topology
 3BYI A;  5IRC A;  1F7C A;  3FK2 A;  1TX4 A;  3CXL A;  3EAP A;  2MBG A;  5C2J A;  1GRN B;  1RGP A;  2OSA A;  3QIS A;  3MSX B;  5JCP A;  2OVJ A;  1XA6 A;  1PBW A;  5JD0 A;  3WPQ A;  2EE4 A;  3KUQ A;  2QV2 A;  3IUG A;  2XS6 A;  1AM4 A;  5C5S A;  1OW3 A;  3WPS A;  2NGR B;  5HPY A;  2EE5 A;  3W6R A; 
#chains in the Genus database with same CATH homology
 3BYI A;  5IRC A;  1F7C A;  3FK2 A;  1TX4 A;  3CXL A;  3EAP A;  2MBG A;  5C2J A;  1GRN B;  1RGP A;  2OSA A;  3QIS A;  3MSX B;  5JCP A;  2OVJ A;  1XA6 A;  1PBW A;  5JD0 A;  3WPQ A;  2EE4 A;  3KUQ A;  2QV2 A;  3IUG A;  2XS6 A;  1AM4 A;  5C5S A;  1OW3 A;  3WPS A;  2NGR B;  5HPY A;  2EE5 A;  3W6R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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