1F7CA

Crystal structure of the bh domain from graf, the gtpase regulator associated with focal adhesion kinase
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
191
structure length
182
Chain Sequence
AQLDSIGFSIIKKCIHAVETRGINEQGLYRIVGVNSRVQKLLSILMDPETEICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLHLLMNHLAKVADNHKQNLMTVANLGVVFGPTLLRPTVAAIMDIKFQNIVIEILIENHEKIFNTVPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the BH domain from graf and its implications for Rho GTPase recognition.
pubmed doi rcsb
molecule tags Signaling protein
source organism Gallus gallus
molecule keywords RHOGAP PROTEIN
total genus 64
structure length 182
sequence length 191
ec nomenclature
pdb deposition date 2000-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1f7cA00
5C2JA 2EE5A 5IRCA 1F7CA 3WPQA 5C5SA 2QV2A 3IUGA 1PBWA 1RGPA 2OVJA 1TX4A 3FK2A 1GRNB 1XA6A 2XS6A 2NGRB 3W6RA 3WPSA 3BYIA 5JD0A 2OSAA 5HPYA 3CXLA 3QISA 2EE4A 1OW3A 3EAPA 5JCPA 2MBGA 3MSXB 3KUQA 1AM4A
chains in the Genus database with same CATH superfamily
5C2JA 2EE5A 5IRCA 1F7CA 3WPQA 5C5SA 2QV2A 3IUGA 1PBWA 1RGPA 2OVJA 1TX4A 3FK2A 1GRNB 1XA6A 2XS6A 2NGRB 3W6RA 3WPSA 3BYIA 5JD0A 2OSAA 5HPYA 3CXLA 3QISA 2EE4A 1OW3A 3EAPA 5JCPA 2MBGA 3MSXB 3KUQA 1AM4A
chains in the Genus database with same CATH topology
5C2JA 2EE5A 5IRCA 1F7CA 3WPQA 5C5SA 2QV2A 3IUGA 1PBWA 1RGPA 2OVJA 1TX4A 3FK2A 1GRNB 1XA6A 2XS6A 2NGRB 3W6RA 3WPSA 3BYIA 5JD0A 2OSAA 5HPYA 3CXLA 3QISA 2EE4A 1OW3A 3EAPA 5JCPA 2MBGA 3MSXB 3KUQA 1AM4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C2J A;  2EE5 A;  5IRC A;  1F7C A;  3WPQ A;  5C5S A;  2QV2 A;  3IUG A;  1PBW A;  1RGP A;  2OVJ A;  1TX4 A;  3FK2 A;  1GRN B;  1XA6 A;  2XS6 A;  2NGR B;  3W6R A;  3WPS A;  3BYI A;  5JD0 A;  2OSA A;  5HPY A;  3CXL A;  3QIS A;  2EE4 A;  1OW3 A;  3EAP A;  5JCP A;  2MBG A;  3MSX B;  3KUQ A;  1AM4 A; 
#chains in the Genus database with same CATH topology
 5C2J A;  2EE5 A;  5IRC A;  1F7C A;  3WPQ A;  5C5S A;  2QV2 A;  3IUG A;  1PBW A;  1RGP A;  2OVJ A;  1TX4 A;  3FK2 A;  1GRN B;  1XA6 A;  2XS6 A;  2NGR B;  3W6R A;  3WPS A;  3BYI A;  5JD0 A;  2OSA A;  5HPY A;  3CXL A;  3QIS A;  2EE4 A;  1OW3 A;  3EAP A;  5JCP A;  2MBG A;  3MSX B;  3KUQ A;  1AM4 A; 
#chains in the Genus database with same CATH homology
 5C2J A;  2EE5 A;  5IRC A;  1F7C A;  3WPQ A;  5C5S A;  2QV2 A;  3IUG A;  1PBW A;  1RGP A;  2OVJ A;  1TX4 A;  3FK2 A;  1GRN B;  1XA6 A;  2XS6 A;  2NGR B;  3W6R A;  3WPS A;  3BYI A;  5JD0 A;  2OSA A;  5HPY A;  3CXL A;  3QIS A;  2EE4 A;  1OW3 A;  3EAP A;  5JCP A;  2MBG A;  3MSX B;  3KUQ A;  1AM4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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