1GRNB

Crystal structure of the cdc42/cdc42gap/alf3 complex.
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
197
structure length
197
Chain Sequence
LPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
pubmed doi rcsb
molecule keywords PROTEIN (GTP BINDING PROTEIN)
molecule tags Gene regulation
source organism Homo sapiens
total genus 64
structure length 197
sequence length 197
ec nomenclature
pdb deposition date 1998-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1grnB00
2QV2A 1GRNB 2MBGA 3W6RA 1RGPA 5IRCA 2OVJA 3BYIA 2EE4A 3EAPA 3MSXB 3WPSA 2XS6A 3QISA 5C5SA 3IUGA 1XA6A 3KUQA 2EE5A 3FK2A 3CXLA 5C2JA 1F7CA 1AM4A 1TX4A 5JCPA 5JD0A 5HPYA 3WPQA 2OSAA 1PBWA 1OW3A 2NGRB
chains in the Genus database with same CATH superfamily
2QV2A 1GRNB 2MBGA 3W6RA 1RGPA 5IRCA 2OVJA 3BYIA 2EE4A 3EAPA 3MSXB 3WPSA 2XS6A 3QISA 5C5SA 3IUGA 1XA6A 3KUQA 2EE5A 3FK2A 3CXLA 5C2JA 1F7CA 1AM4A 1TX4A 5JCPA 5JD0A 5HPYA 3WPQA 2OSAA 1PBWA 1OW3A 2NGRB
chains in the Genus database with same CATH topology
2QV2A 1GRNB 2MBGA 3W6RA 1RGPA 5IRCA 2OVJA 3BYIA 2EE4A 3EAPA 3MSXB 3WPSA 2XS6A 3QISA 5C5SA 3IUGA 1XA6A 3KUQA 2EE5A 3FK2A 3CXLA 5C2JA 1F7CA 1AM4A 1TX4A 5JCPA 5JD0A 5HPYA 3WPQA 2OSAA 1PBWA 1OW3A 2NGRB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QV2 A;  1GRN B;  2MBG A;  3W6R A;  1RGP A;  5IRC A;  2OVJ A;  3BYI A;  2EE4 A;  3EAP A;  3MSX B;  3WPS A;  2XS6 A;  3QIS A;  5C5S A;  3IUG A;  1XA6 A;  3KUQ A;  2EE5 A;  3FK2 A;  3CXL A;  5C2J A;  1F7C A;  1AM4 A;  1TX4 A;  5JCP A;  5JD0 A;  5HPY A;  3WPQ A;  2OSA A;  1PBW A;  1OW3 A;  2NGR B; 
#chains in the Genus database with same CATH topology
 2QV2 A;  1GRN B;  2MBG A;  3W6R A;  1RGP A;  5IRC A;  2OVJ A;  3BYI A;  2EE4 A;  3EAP A;  3MSX B;  3WPS A;  2XS6 A;  3QIS A;  5C5S A;  3IUG A;  1XA6 A;  3KUQ A;  2EE5 A;  3FK2 A;  3CXL A;  5C2J A;  1F7C A;  1AM4 A;  1TX4 A;  5JCP A;  5JD0 A;  5HPY A;  3WPQ A;  2OSA A;  1PBW A;  1OW3 A;  2NGR B; 
#chains in the Genus database with same CATH homology
 2QV2 A;  1GRN B;  2MBG A;  3W6R A;  1RGP A;  5IRC A;  2OVJ A;  3BYI A;  2EE4 A;  3EAP A;  3MSX B;  3WPS A;  2XS6 A;  3QIS A;  5C5S A;  3IUG A;  1XA6 A;  3KUQ A;  2EE5 A;  3FK2 A;  3CXL A;  5C2J A;  1F7C A;  1AM4 A;  1TX4 A;  5JCP A;  5JD0 A;  5HPY A;  3WPQ A;  2OSA A;  1PBW A;  1OW3 A;  2NGR B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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