1GRNB

Crystal structure of the cdc42/cdc42gap/alf3 complex.
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
197
structure length
197
Chain Sequence
LPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
pubmed doi rcsb
molecule tags Gene regulation
source organism Homo sapiens
molecule keywords PROTEIN (GTP BINDING PROTEIN)
total genus 64
structure length 197
sequence length 197
ec nomenclature
pdb deposition date 1998-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1grnB00
2XS6A 5HPYA 2NGRB 3W6RA 5JD0A 1OW3A 5IRCA 2QV2A 3MSXB 3EAPA 1RGPA 2OVJA 1TX4A 5C2JA 5C5SA 5JCPA 1AM4A 2OSAA 1F7CA 2EE4A 3KUQA 3BYIA 3CXLA 2EE5A 3IUGA 1XA6A 3QISA 1GRNB 2MBGA 1PBWA 3FK2A 3WPSA 3WPQA
chains in the Genus database with same CATH superfamily
2XS6A 5HPYA 2NGRB 3W6RA 5JD0A 1OW3A 5IRCA 2QV2A 3MSXB 3EAPA 1RGPA 2OVJA 1TX4A 5C2JA 5C5SA 5JCPA 1AM4A 2OSAA 1F7CA 2EE4A 3KUQA 3BYIA 3CXLA 2EE5A 3IUGA 1XA6A 3QISA 1GRNB 2MBGA 1PBWA 3FK2A 3WPSA 3WPQA
chains in the Genus database with same CATH topology
2XS6A 5HPYA 2NGRB 3W6RA 5JD0A 1OW3A 5IRCA 2QV2A 3MSXB 3EAPA 1RGPA 2OVJA 1TX4A 5C2JA 5C5SA 5JCPA 1AM4A 2OSAA 1F7CA 2EE4A 3KUQA 3BYIA 3CXLA 2EE5A 3IUGA 1XA6A 3QISA 1GRNB 2MBGA 1PBWA 3FK2A 3WPSA 3WPQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XS6 A;  5HPY A;  2NGR B;  3W6R A;  5JD0 A;  1OW3 A;  5IRC A;  2QV2 A;  3MSX B;  3EAP A;  1RGP A;  2OVJ A;  1TX4 A;  5C2J A;  5C5S A;  5JCP A;  1AM4 A;  2OSA A;  1F7C A;  2EE4 A;  3KUQ A;  3BYI A;  3CXL A;  2EE5 A;  3IUG A;  1XA6 A;  3QIS A;  1GRN B;  2MBG A;  1PBW A;  3FK2 A;  3WPS A;  3WPQ A; 
#chains in the Genus database with same CATH topology
 2XS6 A;  5HPY A;  2NGR B;  3W6R A;  5JD0 A;  1OW3 A;  5IRC A;  2QV2 A;  3MSX B;  3EAP A;  1RGP A;  2OVJ A;  1TX4 A;  5C2J A;  5C5S A;  5JCP A;  1AM4 A;  2OSA A;  1F7C A;  2EE4 A;  3KUQ A;  3BYI A;  3CXL A;  2EE5 A;  3IUG A;  1XA6 A;  3QIS A;  1GRN B;  2MBG A;  1PBW A;  3FK2 A;  3WPS A;  3WPQ A; 
#chains in the Genus database with same CATH homology
 2XS6 A;  5HPY A;  2NGR B;  3W6R A;  5JD0 A;  1OW3 A;  5IRC A;  2QV2 A;  3MSX B;  3EAP A;  1RGP A;  2OVJ A;  1TX4 A;  5C2J A;  5C5S A;  5JCP A;  1AM4 A;  2OSA A;  1F7C A;  2EE4 A;  3KUQ A;  3BYI A;  3CXL A;  2EE5 A;  3IUG A;  1XA6 A;  3QIS A;  1GRN B;  2MBG A;  1PBW A;  3FK2 A;  3WPS A;  3WPQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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