1GT0D

Crystal structure of a pou/hmg/dna ternary complex
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
79
structure length
79
Chain Sequence
DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of a POU/Hmg/DNA Ternary Complex Suggests Differential Assembly of Oct4 and Sox2 on Two Enhancers
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords 5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*TP*TP* GP*GP*AP* TP*GP*CP*TP*A
total genus 21
structure length 79
sequence length 79
ec nomenclature
pdb deposition date 2002-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00505 HMG_box HMG (high mobility group) box
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 1gt0D00
2EQZA 1HMEA 2CS1A 2YQIA 1HRZA 3FGHA 1HRYA 1CG7A 1J3DA 2YUKA 2LY4A 1GT0D 1HSMA 2D7LA 1HMAA 1J5NA 4A3NA 4S2QD 1J47A 4NNUA 1J3CA 3F27D 2CO9A 1I11A 1HMFA 2HDZA 2YULA 1E7JA 2YRQA 1V64A 1L8YA 2CTOA 2E6OA 1CKTA 1WZ6A 1LWMA 2GZKA 2RTUA 3NM9A 1L8ZA 1QRVA 3U2BC 2LE4A 1HSNA 1NHMA 2LEFA 1AABA 1K99A 2LHJA 1V63A 1J46A 1WGFA 1O4XB 4Y60C 1WXLA 3TQ6A 4NODA 4QR9A 1J3XA 1NHNA 4EUWA 3TMMA 2CRJA
chains in the Genus database with same CATH superfamily
2EQZA 1HMEA 2CS1A 2YQIA 3ABRB 1HRZA 3FGHA 1HRYA 1CG7A 1J3DA 4A15A 2YUKA 2LY4A 1GT0D 1HSMA 2D7LA 1HMAA 1J5NA 4A3NA 4S2QD 1J47A 4NNUA 1J3CA 3F27D 2CO9A 5H8WA 3ABSB 1I11A 1HMFA 3ABOB 2HDZA 2YULA 3ANYB 2YRQA 1V64A 1L8YA 2CTOA 2E6OA 1E7JA 1CKTA 1WZ6A 1LWMA 2GZKA 2RTUA 3NM9A 1L8ZA 1QRVA 3U2BC 2VSFA 2LE4A 1HSNA 1NHMA 2LEFA 1AABA 1K99A 2LHJA 1V63A 4KQEA 1J46A 1WGFA 3AO0B 1O4XB 4Y60C 1WXLA 3TQ6A 4NODA 4QR9A 1J3XA 1NHNA 4EUWA 3TMMA 2CRJA
chains in the Genus database with same CATH topology
2EQZA 1HMEA 2CS1A 2YQIA 1HRZA 3FGHA 1HRYA 1CG7A 1J3DA 2YUKA 2LY4A 1GT0D 1HSMA 2D7LA 1HMAA 1J5NA 4A3NA 4S2QD 1J47A 4NNUA 1J3CA 3F27D 2CO9A 1I11A 1HMFA 2HDZA 2YULA 1E7JA 2YRQA 1V64A 1L8YA 2CTOA 2E6OA 1CKTA 1WZ6A 1LWMA 2GZKA 2RTUA 3NM9A 1L8ZA 1QRVA 3U2BC 2LE4A 1HSNA 1NHMA 2LEFA 1AABA 1K99A 2LHJA 1V63A 1J46A 1WGFA 1O4XB 4Y60C 1WXLA 3TQ6A 4NODA 4QR9A 1J3XA 1NHNA 4EUWA 3TMMA 2CRJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EQZ A;  1HME A;  2CS1 A;  2YQI A;  1HRZ A;  3FGH A;  1HRY A;  1CG7 A;  1J3D A;  2YUK A;  2LY4 A;  1GT0 D;  1HSM A;  2D7L A;  1HMA A;  1J5N A;  4A3N A;  4S2Q D;  1J47 A;  4NNU A;  1J3C A;  3F27 D;  2CO9 A;  1I11 A;  1HMF A;  2HDZ A;  2YUL A;  1E7J A;  2YRQ A;  1V64 A;  1L8Y A;  2CTO A;  2E6O A;  1CKT A;  1WZ6 A;  1LWM A;  2GZK A;  2RTU A;  3NM9 A;  1L8Z A;  1QRV A;  3U2B C;  2LE4 A;  1HSN A;  1NHM A;  2LEF A;  1AAB A;  1K99 A;  2LHJ A;  1V63 A;  1J46 A;  1WGF A;  1O4X B;  4Y60 C;  1WXL A;  3TQ6 A;  4NOD A;  4QR9 A;  1J3X A;  1NHN A;  4EUW A;  3TMM A;  2CRJ A; 
#chains in the Genus database with same CATH topology
 2EQZ A;  1HME A;  2CS1 A;  2YQI A;  3ABR B;  1HRZ A;  3FGH A;  1HRY A;  1CG7 A;  1J3D A;  4A15 A;  2YUK A;  2LY4 A;  1GT0 D;  1HSM A;  2D7L A;  1HMA A;  1J5N A;  4A3N A;  4S2Q D;  1J47 A;  4NNU A;  1J3C A;  3F27 D;  2CO9 A;  5H8W A;  3ABS B;  1I11 A;  1HMF A;  3ABO B;  2HDZ A;  2YUL A;  3ANY B;  2YRQ A;  1V64 A;  1L8Y A;  2CTO A;  2E6O A;  1E7J A;  1CKT A;  1WZ6 A;  1LWM A;  2GZK A;  2RTU A;  3NM9 A;  1L8Z A;  1QRV A;  3U2B C;  2VSF A;  2LE4 A;  1HSN A;  1NHM A;  2LEF A;  1AAB A;  1K99 A;  2LHJ A;  1V63 A;  4KQE A;  1J46 A;  1WGF A;  3AO0 B;  1O4X B;  4Y60 C;  1WXL A;  3TQ6 A;  4NOD A;  4QR9 A;  1J3X A;  1NHN A;  4EUW A;  3TMM A;  2CRJ A; 
#chains in the Genus database with same CATH homology
 2EQZ A;  1HME A;  2CS1 A;  2YQI A;  1HRZ A;  3FGH A;  1HRY A;  1CG7 A;  1J3D A;  2YUK A;  2LY4 A;  1GT0 D;  1HSM A;  2D7L A;  1HMA A;  1J5N A;  4A3N A;  4S2Q D;  1J47 A;  4NNU A;  1J3C A;  3F27 D;  2CO9 A;  1I11 A;  1HMF A;  2HDZ A;  2YUL A;  1E7J A;  2YRQ A;  1V64 A;  1L8Y A;  2CTO A;  2E6O A;  1CKT A;  1WZ6 A;  1LWM A;  2GZK A;  2RTU A;  3NM9 A;  1L8Z A;  1QRV A;  3U2B C;  2LE4 A;  1HSN A;  1NHM A;  2LEF A;  1AAB A;  1K99 A;  2LHJ A;  1V63 A;  1J46 A;  1WGF A;  1O4X B;  4Y60 C;  1WXL A;  3TQ6 A;  4NOD A;  4QR9 A;  1J3X A;  1NHN A;  4EUW A;  3TMM A;  2CRJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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