1HRZA

The 3d structure of the human sry-dna complex solved by multi-dimensional heteronuclear-edited and-filtered nmr
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
73
structure length
73
Chain Sequence
DRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAMHREKYPNYKYR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex.
pubmed doi rcsb
molecule tags Dna binding protein/dna
molecule keywords DNA (5'-D(*GP*CP*AP*CP*AP*AP*AP*C)-3')
total genus 19
structure length 73
sequence length 73
ec nomenclature
pdb deposition date 1995-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00505 HMG_box HMG (high mobility group) box
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 1hrzA00
4NNUA 1GT0D 1CG7A 3TMMA 3NM9A 1J3XA 4S2QD 1J47A 2RTUA 1WGFA 1J5NA 4NODA 2LHJA 1HSMA 1V64A 2CS1A 2HDZA 2YUKA 2EQZA 2YULA 4A3NA 2LY4A 2YRQA 1HRZA 1QRVA 2GZKA 1HSNA 2D7LA 3TQ6A 1L8YA 1HMEA 1J46A 2CO9A 1L8ZA 2E6OA 4Y60C 1AABA 1V63A 3F27D 1J3DA 1WZ6A 2LEFA 3U2BC 1HMAA 1O4XB 1J3CA 1NHMA 1NHNA 1I11A 1HMFA 4EUWA 1HRYA 1WXLA 1E7JA 2CRJA 2LE4A 1CKTA 1LWMA 1K99A 2CTOA 3FGHA 2YQIA 4QR9A
chains in the Genus database with same CATH superfamily
4NNUA 1GT0D 1CG7A 3TMMA 3NM9A 1J3XA 4S2QD 1J47A 2RTUA 1WGFA 2VSFA 1J5NA 4NODA 2LHJA 1HSMA 1V64A 2CS1A 2HDZA 2YUKA 2EQZA 3ABSB 2YULA 3ANYB 4A3NA 2LY4A 2YRQA 1HRZA 1QRVA 2GZKA 1HSNA 2D7LA 3TQ6A 1L8YA 1HMEA 1J46A 2CO9A 1L8ZA 2E6OA 4KQEA 4Y60C 1AABA 1V63A 3F27D 4A15A 1J3DA 1WZ6A 3ABOB 3AO0B 3U2BC 2LEFA 1HMAA 1O4XB 1J3CA 1NHMA 1NHNA 1I11A 5H8WA 1HMFA 4EUWA 1HRYA 1WXLA 1E7JA 2CRJA 2LE4A 3ABRB 1CKTA 1LWMA 1K99A 2CTOA 3FGHA 2YQIA 4QR9A
chains in the Genus database with same CATH topology
4NNUA 1GT0D 1CG7A 3TMMA 3NM9A 1J3XA 4S2QD 1J47A 2RTUA 1WGFA 1J5NA 4NODA 2LHJA 1HSMA 1V64A 2CS1A 2HDZA 2YUKA 2EQZA 2YULA 4A3NA 2LY4A 2YRQA 1HRZA 1QRVA 2GZKA 1HSNA 2D7LA 3TQ6A 1L8YA 1HMEA 1J46A 2CO9A 1L8ZA 2E6OA 4Y60C 1AABA 1V63A 3F27D 1J3DA 1WZ6A 2LEFA 3U2BC 1HMAA 1O4XB 1J3CA 1NHMA 1NHNA 1I11A 1HMFA 4EUWA 1HRYA 1WXLA 1E7JA 2CRJA 2LE4A 1CKTA 1LWMA 1K99A 2CTOA 3FGHA 2YQIA 4QR9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NNU A;  1GT0 D;  1CG7 A;  3TMM A;  3NM9 A;  1J3X A;  4S2Q D;  1J47 A;  2RTU A;  1WGF A;  1J5N A;  4NOD A;  2LHJ A;  1HSM A;  1V64 A;  2CS1 A;  2HDZ A;  2YUK A;  2EQZ A;  2YUL A;  4A3N A;  2LY4 A;  2YRQ A;  1HRZ A;  1QRV A;  2GZK A;  1HSN A;  2D7L A;  3TQ6 A;  1L8Y A;  1HME A;  1J46 A;  2CO9 A;  1L8Z A;  2E6O A;  4Y60 C;  1AAB A;  1V63 A;  3F27 D;  1J3D A;  1WZ6 A;  2LEF A;  3U2B C;  1HMA A;  1O4X B;  1J3C A;  1NHM A;  1NHN A;  1I11 A;  1HMF A;  4EUW A;  1HRY A;  1WXL A;  1E7J A;  2CRJ A;  2LE4 A;  1CKT A;  1LWM A;  1K99 A;  2CTO A;  3FGH A;  2YQI A;  4QR9 A; 
#chains in the Genus database with same CATH topology
 4NNU A;  1GT0 D;  1CG7 A;  3TMM A;  3NM9 A;  1J3X A;  4S2Q D;  1J47 A;  2RTU A;  1WGF A;  2VSF A;  1J5N A;  4NOD A;  2LHJ A;  1HSM A;  1V64 A;  2CS1 A;  2HDZ A;  2YUK A;  2EQZ A;  3ABS B;  2YUL A;  3ANY B;  4A3N A;  2LY4 A;  2YRQ A;  1HRZ A;  1QRV A;  2GZK A;  1HSN A;  2D7L A;  3TQ6 A;  1L8Y A;  1HME A;  1J46 A;  2CO9 A;  1L8Z A;  2E6O A;  4KQE A;  4Y60 C;  1AAB A;  1V63 A;  3F27 D;  4A15 A;  1J3D A;  1WZ6 A;  3ABO B;  3AO0 B;  3U2B C;  2LEF A;  1HMA A;  1O4X B;  1J3C A;  1NHM A;  1NHN A;  1I11 A;  5H8W A;  1HMF A;  4EUW A;  1HRY A;  1WXL A;  1E7J A;  2CRJ A;  2LE4 A;  3ABR B;  1CKT A;  1LWM A;  1K99 A;  2CTO A;  3FGH A;  2YQI A;  4QR9 A; 
#chains in the Genus database with same CATH homology
 4NNU A;  1GT0 D;  1CG7 A;  3TMM A;  3NM9 A;  1J3X A;  4S2Q D;  1J47 A;  2RTU A;  1WGF A;  1J5N A;  4NOD A;  2LHJ A;  1HSM A;  1V64 A;  2CS1 A;  2HDZ A;  2YUK A;  2EQZ A;  2YUL A;  4A3N A;  2LY4 A;  2YRQ A;  1HRZ A;  1QRV A;  2GZK A;  1HSN A;  2D7L A;  3TQ6 A;  1L8Y A;  1HME A;  1J46 A;  2CO9 A;  1L8Z A;  2E6O A;  4Y60 C;  1AAB A;  1V63 A;  3F27 D;  1J3D A;  1WZ6 A;  2LEF A;  3U2B C;  1HMA A;  1O4X B;  1J3C A;  1NHM A;  1NHN A;  1I11 A;  1HMF A;  4EUW A;  1HRY A;  1WXL A;  1E7J A;  2CRJ A;  2LE4 A;  1CKT A;  1LWM A;  1K99 A;  2CTO A;  3FGH A;  2YQI A;  4QR9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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