1J47A

3d solution nmr structure of the m9i mutant of the hmg-box domain of the human male sex determining factor sry complexed to dna
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
85
structure length
85
Chain Sequence
MQDRVKRPINAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAMHREKYPNYKYRPRRKAKMLPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for SRY-dependent 46-X,Y sex reversal: modulation of DNA bending by a naturally occurring point mutation.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords 5'-D(*CP*CP*TP*GP*CP*AP*CP*AP*AP*AP*CP*AP*CP*C)-3'
total genus 20
structure length 85
sequence length 85
ec nomenclature
pdb deposition date 2001-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00505 HMG_box HMG (high mobility group) box
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 1j47A00
1L8YA 2CS1A 3TQ6A 2GZKA 2YULA 1WGFA 4QR9A 1WZ6A 4NODA 1LWMA 1HMFA 3F27D 1HRYA 2EQZA 1V63A 4A3NA 4Y60C 1J3DA 1L8ZA 2YRQA 1CG7A 2E6OA 1K99A 4S2QD 1NHMA 1J3CA 1E7JA 2CRJA 4NNUA 1HSMA 2CO9A 1J5NA 3U2BC 3TMMA 1WXLA 2D7LA 2LE4A 1AABA 1J46A 1V64A 1NHNA 3NM9A 1O4XB 2HDZA 1HMEA 2YQIA 2CTOA 2YUKA 4EUWA 2LEFA 2RTUA 2LY4A 2LHJA 1CKTA 1HRZA 1I11A 1HMAA 1QRVA 1GT0D 3FGHA 1HSNA 1J3XA 1J47A
chains in the Genus database with same CATH superfamily
1L8YA 2CS1A 4A15A 3TQ6A 2GZKA 3ANYB 2YULA 1WGFA 4QR9A 1WZ6A 4NODA 1LWMA 1HMFA 3F27D 1HRYA 2EQZA 1V63A 4A3NA 4Y60C 1J3DA 1L8ZA 2YRQA 3ABRB 1CG7A 2E6OA 3ABSB 1K99A 4S2QD 1NHMA 1J3CA 1E7JA 2CRJA 4NNUA 1HSMA 2CO9A 1J5NA 3U2BC 3TMMA 1WXLA 2D7LA 2LE4A 1AABA 1J46A 1V64A 1NHNA 3NM9A 1O4XB 3ABOB 3AO0B 2HDZA 1HMEA 2YQIA 2CTOA 2YUKA 4EUWA 5H8WA 2LEFA 2RTUA 2LY4A 2LHJA 1CKTA 1HRZA 4KQEA 1I11A 1HMAA 2VSFA 1QRVA 1GT0D 3FGHA 1HSNA 1J3XA 1J47A
chains in the Genus database with same CATH topology
1L8YA 2CS1A 3TQ6A 2GZKA 2YULA 1WGFA 4QR9A 1WZ6A 4NODA 1LWMA 1HMFA 3F27D 1HRYA 2EQZA 1V63A 4A3NA 4Y60C 1J3DA 1L8ZA 2YRQA 1CG7A 2E6OA 1K99A 4S2QD 1NHMA 1J3CA 1E7JA 2CRJA 4NNUA 1HSMA 2CO9A 1J5NA 3U2BC 3TMMA 1WXLA 2D7LA 2LE4A 1AABA 1J46A 1V64A 1NHNA 3NM9A 1O4XB 2HDZA 1HMEA 2YQIA 2CTOA 2YUKA 4EUWA 2LEFA 2RTUA 2LY4A 2LHJA 1CKTA 1HRZA 1I11A 1HMAA 1QRVA 1GT0D 3FGHA 1HSNA 1J3XA 1J47A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1L8Y A;  2CS1 A;  3TQ6 A;  2GZK A;  2YUL A;  1WGF A;  4QR9 A;  1WZ6 A;  4NOD A;  1LWM A;  1HMF A;  3F27 D;  1HRY A;  2EQZ A;  1V63 A;  4A3N A;  4Y60 C;  1J3D A;  1L8Z A;  2YRQ A;  1CG7 A;  2E6O A;  1K99 A;  4S2Q D;  1NHM A;  1J3C A;  1E7J A;  2CRJ A;  4NNU A;  1HSM A;  2CO9 A;  1J5N A;  3U2B C;  3TMM A;  1WXL A;  2D7L A;  2LE4 A;  1AAB A;  1J46 A;  1V64 A;  1NHN A;  3NM9 A;  1O4X B;  2HDZ A;  1HME A;  2YQI A;  2CTO A;  2YUK A;  4EUW A;  2LEF A;  2RTU A;  2LY4 A;  2LHJ A;  1CKT A;  1HRZ A;  1I11 A;  1HMA A;  1QRV A;  1GT0 D;  3FGH A;  1HSN A;  1J3X A;  1J47 A; 
#chains in the Genus database with same CATH topology
 1L8Y A;  2CS1 A;  4A15 A;  3TQ6 A;  2GZK A;  3ANY B;  2YUL A;  1WGF A;  4QR9 A;  1WZ6 A;  4NOD A;  1LWM A;  1HMF A;  3F27 D;  1HRY A;  2EQZ A;  1V63 A;  4A3N A;  4Y60 C;  1J3D A;  1L8Z A;  2YRQ A;  3ABR B;  1CG7 A;  2E6O A;  3ABS B;  1K99 A;  4S2Q D;  1NHM A;  1J3C A;  1E7J A;  2CRJ A;  4NNU A;  1HSM A;  2CO9 A;  1J5N A;  3U2B C;  3TMM A;  1WXL A;  2D7L A;  2LE4 A;  1AAB A;  1J46 A;  1V64 A;  1NHN A;  3NM9 A;  1O4X B;  3ABO B;  3AO0 B;  2HDZ A;  1HME A;  2YQI A;  2CTO A;  2YUK A;  4EUW A;  5H8W A;  2LEF A;  2RTU A;  2LY4 A;  2LHJ A;  1CKT A;  1HRZ A;  4KQE A;  1I11 A;  1HMA A;  2VSF A;  1QRV A;  1GT0 D;  3FGH A;  1HSN A;  1J3X A;  1J47 A; 
#chains in the Genus database with same CATH homology
 1L8Y A;  2CS1 A;  3TQ6 A;  2GZK A;  2YUL A;  1WGF A;  4QR9 A;  1WZ6 A;  4NOD A;  1LWM A;  1HMF A;  3F27 D;  1HRY A;  2EQZ A;  1V63 A;  4A3N A;  4Y60 C;  1J3D A;  1L8Z A;  2YRQ A;  1CG7 A;  2E6O A;  1K99 A;  4S2Q D;  1NHM A;  1J3C A;  1E7J A;  2CRJ A;  4NNU A;  1HSM A;  2CO9 A;  1J5N A;  3U2B C;  3TMM A;  1WXL A;  2D7L A;  2LE4 A;  1AAB A;  1J46 A;  1V64 A;  1NHN A;  3NM9 A;  1O4X B;  2HDZ A;  1HME A;  2YQI A;  2CTO A;  2YUK A;  4EUW A;  2LEF A;  2RTU A;  2LY4 A;  2LHJ A;  1CKT A;  1HRZ A;  1I11 A;  1HMA A;  1QRV A;  1GT0 D;  3FGH A;  1HSN A;  1J3X A;  1J47 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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