1KPLA

Crystal structure of the clc chloride channel from s. typhimurium
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
430
structure length
430
Chain Sequence
TPLAILFMAAVVGTLTGLVGVAFEKAVSWVQNMRIGALVQVADHAFLLWPLAFILSALLAMVGYFLVRKFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFRMRSAEARHTLLATGAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFRIFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGVVGPVFNSLVLRTQDMFQRFHGGEIKKWVLMGGAIGGLCGILGLIEPAAAGGGFNLIPIAAAGNFSVGLLLFIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFPQYHLEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILARTLAKQDAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
pubmed doi rcsb
molecule keywords putative ClC family, chlorine transport protein
molecule tags Membrane protein
source organism Salmonella typhimurium
total genus 166
structure length 430
sequence length 430
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2001-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 1kplA00
4FTPA 2FECA 4KKBA 2H2SA 4KK6A 2FEDA 3ORGA 4KKAA 4KK9A 4KKLA 4KJQA 2EZ0A 4KJWA 2HLFA 2HT2A 2FEEA 2HT4A 4KKCA 4KK8A 3Q17A 2HTLA 1OTUA 2R9HA 1OTTA 2EXYA 3ND0A 4ENEA 5HD8A 3EJZA 1KPLA 4LOUA 3DETA 1KPKA 3EJYA 4FG6A 2EXWA 2H2PA 2HT3A 4KK5A 1OTSA 3NMOA 4MQXA 4KJPA 2HTKA
chains in the Genus database with same CATH superfamily
4FTPA 2FECA 4KKBA 2H2SA 4KK6A 2FEDA 3ORGA 4KKAA 4KK9A 4KKLA 4KJQA 2EZ0A 4KJWA 2HLFA 2HT2A 2FEEA 2HT4A 4KKCA 4KK8A 3Q17A 2HTLA 1OTUA 2R9HA 1OTTA 2EXYA 3ND0A 4ENEA 5HD8A 3EJZA 1KPLA 4LOUA 3DETA 1KPKA 3EJYA 4FG6A 2EXWA 2H2PA 2HT3A 4KK5A 1OTSA 3NMOA 4MQXA 4KJPA 2HTKA
chains in the Genus database with same CATH topology
4FTPA 2FECA 4KKBA 2H2SA 4KK6A 2FEDA 3ORGA 4KKAA 4KK9A 4KKLA 4KJQA 2EZ0A 4KJWA 2HLFA 2HT2A 2FEEA 2HT4A 4KKCA 4KK8A 3Q17A 2HTLA 1OTUA 2R9HA 1OTTA 2EXYA 3ND0A 4ENEA 5HD8A 3EJZA 1KPLA 4LOUA 3DETA 1KPKA 3EJYA 4FG6A 2EXWA 2H2PA 2HT3A 4KK5A 1OTSA 3NMOA 4MQXA 4KJPA 2HTKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FTP A;  2FEC A;  4KKB A;  2H2S A;  4KK6 A;  2FED A;  3ORG A;  4KKA A;  4KK9 A;  4KKL A;  4KJQ A;  2EZ0 A;  4KJW A;  2HLF A;  2HT2 A;  2FEE A;  2HT4 A;  4KKC A;  4KK8 A;  3Q17 A;  2HTL A;  1OTU A;  2R9H A;  1OTT A;  2EXY A;  3ND0 A;  4ENE A;  5HD8 A;  3EJZ A;  1KPL A;  4LOU A;  3DET A;  1KPK A;  3EJY A;  4FG6 A;  2EXW A;  2H2P A;  2HT3 A;  4KK5 A;  1OTS A;  3NMO A;  4MQX A;  4KJP A;  2HTK A; 
#chains in the Genus database with same CATH topology
 4FTP A;  2FEC A;  4KKB A;  2H2S A;  4KK6 A;  2FED A;  3ORG A;  4KKA A;  4KK9 A;  4KKL A;  4KJQ A;  2EZ0 A;  4KJW A;  2HLF A;  2HT2 A;  2FEE A;  2HT4 A;  4KKC A;  4KK8 A;  3Q17 A;  2HTL A;  1OTU A;  2R9H A;  1OTT A;  2EXY A;  3ND0 A;  4ENE A;  5HD8 A;  3EJZ A;  1KPL A;  4LOU A;  3DET A;  1KPK A;  3EJY A;  4FG6 A;  2EXW A;  2H2P A;  2HT3 A;  4KK5 A;  1OTS A;  3NMO A;  4MQX A;  4KJP A;  2HTK A; 
#chains in the Genus database with same CATH homology
 4FTP A;  2FEC A;  4KKB A;  2H2S A;  4KK6 A;  2FED A;  3ORG A;  4KKA A;  4KK9 A;  4KKL A;  4KJQ A;  2EZ0 A;  4KJW A;  2HLF A;  2HT2 A;  2FEE A;  2HT4 A;  4KKC A;  4KK8 A;  3Q17 A;  2HTL A;  1OTU A;  2R9H A;  1OTT A;  2EXY A;  3ND0 A;  4ENE A;  5HD8 A;  3EJZ A;  1KPL A;  4LOU A;  3DET A;  1KPK A;  3EJY A;  4FG6 A;  2EXW A;  2H2P A;  2HT3 A;  4KK5 A;  1OTS A;  3NMO A;  4MQX A;  4KJP A;  2HTK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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