1KPLA

Crystal structure of the clc chloride channel from s. typhimurium
Total Genus 166
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
430
structure length
430
Chain Sequence
TPLAILFMAAVVGTLTGLVGVAFEKAVSWVQNMRIGALVQVADHAFLLWPLAFILSALLAMVGYFLVRKFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFRMRSAEARHTLLATGAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFRIFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGVVGPVFNSLVLRTQDMFQRFHGGEIKKWVLMGGAIGGLCGILGLIEPAAAGGGFNLIPIAAAGNFSVGLLLFIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFPQYHLEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILARTLAKQDAEQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
pubmed doi rcsb
molecule tags Membrane protein
source organism Salmonella typhimurium
molecule keywords putative ClC family, chlorine transport protein
total genus 166
structure length 430
sequence length 430
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2001-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 1kplA00
1OTUA 2FECA 5HD8A 4LOUA 2H2SA 3EJYA 4KK6A 4KKBA 2HT3A 4KKCA 4KKAA 4KJQA 1OTTA 4MQXA 4KJPA 1OTSA 2EXWA 4FG6A 1KPKA 2R9HA 2EXYA 2HT4A 4FTPA 4KK9A 2HTLA 2FEDA 4KJWA 1KPLA 2HLFA 3NMOA 3ND0A 4KK8A 4ENEA 3Q17A 2HTKA 3EJZA 2FEEA 2HT2A 2EZ0A 3DETA 2H2PA 4KKLA 3ORGA 4KK5A
chains in the Genus database with same CATH superfamily
1OTUA 2FECA 5HD8A 4LOUA 2H2SA 3EJYA 4KK6A 4KKBA 2HT3A 4KKCA 4KKAA 4KJQA 1OTTA 4MQXA 4KJPA 1OTSA 2EXWA 4FG6A 1KPKA 2R9HA 2EXYA 2HT4A 4FTPA 4KK9A 2HTLA 2FEDA 4KJWA 1KPLA 2HLFA 3NMOA 3ND0A 4KK8A 4ENEA 3Q17A 2HTKA 3EJZA 2FEEA 2HT2A 2EZ0A 3DETA 2H2PA 4KKLA 3ORGA 4KK5A
chains in the Genus database with same CATH topology
1OTUA 2FECA 5HD8A 4LOUA 2H2SA 3EJYA 4KK6A 4KKBA 2HT3A 4KKCA 4KKAA 4KJQA 1OTTA 4MQXA 4KJPA 1OTSA 2EXWA 4FG6A 1KPKA 2R9HA 2EXYA 2HT4A 4FTPA 4KK9A 2HTLA 2FEDA 4KJWA 1KPLA 2HLFA 3NMOA 3ND0A 4KK8A 4ENEA 3Q17A 2HTKA 3EJZA 2FEEA 2HT2A 2EZ0A 3DETA 2H2PA 4KKLA 3ORGA 4KK5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OTU A;  2FEC A;  5HD8 A;  4LOU A;  2H2S A;  3EJY A;  4KK6 A;  4KKB A;  2HT3 A;  4KKC A;  4KKA A;  4KJQ A;  1OTT A;  4MQX A;  4KJP A;  1OTS A;  2EXW A;  4FG6 A;  1KPK A;  2R9H A;  2EXY A;  2HT4 A;  4FTP A;  4KK9 A;  2HTL A;  2FED A;  4KJW A;  1KPL A;  2HLF A;  3NMO A;  3ND0 A;  4KK8 A;  4ENE A;  3Q17 A;  2HTK A;  3EJZ A;  2FEE A;  2HT2 A;  2EZ0 A;  3DET A;  2H2P A;  4KKL A;  3ORG A;  4KK5 A; 
#chains in the Genus database with same CATH topology
 1OTU A;  2FEC A;  5HD8 A;  4LOU A;  2H2S A;  3EJY A;  4KK6 A;  4KKB A;  2HT3 A;  4KKC A;  4KKA A;  4KJQ A;  1OTT A;  4MQX A;  4KJP A;  1OTS A;  2EXW A;  4FG6 A;  1KPK A;  2R9H A;  2EXY A;  2HT4 A;  4FTP A;  4KK9 A;  2HTL A;  2FED A;  4KJW A;  1KPL A;  2HLF A;  3NMO A;  3ND0 A;  4KK8 A;  4ENE A;  3Q17 A;  2HTK A;  3EJZ A;  2FEE A;  2HT2 A;  2EZ0 A;  3DET A;  2H2P A;  4KKL A;  3ORG A;  4KK5 A; 
#chains in the Genus database with same CATH homology
 1OTU A;  2FEC A;  5HD8 A;  4LOU A;  2H2S A;  3EJY A;  4KK6 A;  4KKB A;  2HT3 A;  4KKC A;  4KKA A;  4KJQ A;  1OTT A;  4MQX A;  4KJP A;  1OTS A;  2EXW A;  4FG6 A;  1KPK A;  2R9H A;  2EXY A;  2HT4 A;  4FTP A;  4KK9 A;  2HTL A;  2FED A;  4KJW A;  1KPL A;  2HLF A;  3NMO A;  3ND0 A;  4KK8 A;  4ENE A;  3Q17 A;  2HTK A;  3EJZ A;  2FEE A;  2HT2 A;  2EZ0 A;  3DET A;  2H2P A;  4KKL A;  3ORG A;  4KK5 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...