4KK6A

Structure of clc-ec1 deltanc construct in 20mm bromide
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
443
structure length
443
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords H(+)/Cl(-) exchange transporter ClcA
publication title Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
pubmed doi rcsb
source organism Escherichia coli
total genus 166
structure length 443
sequence length 443
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 4kk6A00
2EXYA 2FECA 4KJPA 4FG6A 4KKAA 3ORGA 2HT2A 4KJWA 2H2PA 4KK5A 4LOUA 2H2SA 1OTTA 2R9HA 3Q17A 4MQXA 1KPLA 2EZ0A 3NMOA 4FTPA 3EJYA 2HTLA 4ENEA 1KPKA 2HLFA 1OTUA 3ND0A 4KKCA 5HD8A 4KKLA 3EJZA 1OTSA 4KKBA 4KK6A 2HTKA 2FEDA 4KJQA 2HT3A 2EXWA 3DETA 2HT4A 2FEEA 4KK8A 4KK9A
chains in the Genus database with same CATH superfamily
2EXYA 2FECA 4KJPA 4FG6A 4KKAA 3ORGA 2HT2A 4KJWA 2H2PA 4KK5A 4LOUA 2H2SA 1OTTA 2R9HA 3Q17A 4MQXA 1KPLA 2EZ0A 3NMOA 4FTPA 3EJYA 2HTLA 4ENEA 1KPKA 2HLFA 1OTUA 3ND0A 4KKCA 5HD8A 4KKLA 3EJZA 1OTSA 4KKBA 4KK6A 2HTKA 2FEDA 4KJQA 2HT3A 2EXWA 3DETA 2HT4A 2FEEA 4KK8A 4KK9A
chains in the Genus database with same CATH topology
2EXYA 2FECA 4KJPA 4FG6A 4KKAA 3ORGA 2HT2A 4KJWA 2H2PA 4KK5A 4LOUA 2H2SA 1OTTA 2R9HA 3Q17A 4MQXA 1KPLA 2EZ0A 3NMOA 4FTPA 3EJYA 2HTLA 4ENEA 1KPKA 2HLFA 1OTUA 3ND0A 4KKCA 5HD8A 4KKLA 3EJZA 1OTSA 4KKBA 4KK6A 2HTKA 2FEDA 4KJQA 2HT3A 2EXWA 3DETA 2HT4A 2FEEA 4KK8A 4KK9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EXY A;  2FEC A;  4KJP A;  4FG6 A;  4KKA A;  3ORG A;  2HT2 A;  4KJW A;  2H2P A;  4KK5 A;  4LOU A;  2H2S A;  1OTT A;  2R9H A;  3Q17 A;  4MQX A;  1KPL A;  2EZ0 A;  3NMO A;  4FTP A;  3EJY A;  2HTL A;  4ENE A;  1KPK A;  2HLF A;  1OTU A;  3ND0 A;  4KKC A;  5HD8 A;  4KKL A;  3EJZ A;  1OTS A;  4KKB A;  4KK6 A;  2HTK A;  2FED A;  4KJQ A;  2HT3 A;  2EXW A;  3DET A;  2HT4 A;  2FEE A;  4KK8 A;  4KK9 A; 
#chains in the Genus database with same CATH topology
 2EXY A;  2FEC A;  4KJP A;  4FG6 A;  4KKA A;  3ORG A;  2HT2 A;  4KJW A;  2H2P A;  4KK5 A;  4LOU A;  2H2S A;  1OTT A;  2R9H A;  3Q17 A;  4MQX A;  1KPL A;  2EZ0 A;  3NMO A;  4FTP A;  3EJY A;  2HTL A;  4ENE A;  1KPK A;  2HLF A;  1OTU A;  3ND0 A;  4KKC A;  5HD8 A;  4KKL A;  3EJZ A;  1OTS A;  4KKB A;  4KK6 A;  2HTK A;  2FED A;  4KJQ A;  2HT3 A;  2EXW A;  3DET A;  2HT4 A;  2FEE A;  4KK8 A;  4KK9 A; 
#chains in the Genus database with same CATH homology
 2EXY A;  2FEC A;  4KJP A;  4FG6 A;  4KKA A;  3ORG A;  2HT2 A;  4KJW A;  2H2P A;  4KK5 A;  4LOU A;  2H2S A;  1OTT A;  2R9H A;  3Q17 A;  4MQX A;  1KPL A;  2EZ0 A;  3NMO A;  4FTP A;  3EJY A;  2HTL A;  4ENE A;  1KPK A;  2HLF A;  1OTU A;  3ND0 A;  4KKC A;  5HD8 A;  4KKL A;  3EJZ A;  1OTS A;  4KKB A;  4KK6 A;  2HTK A;  2FED A;  4KJQ A;  2HT3 A;  2EXW A;  3DET A;  2HT4 A;  2FEE A;  4KK8 A;  4KK9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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