4KJWA

Structure of the clc-ec1 deltanc construct in 100mm fluoride and 20mm bromide
Total Genus 178
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
178
sequence length
444
structure length
444
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein, membrane protein
molecule keywords H(+)/Cl(-) exchange transporter ClcA
publication title Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
pubmed doi rcsb
source organism Escherichia coli
total genus 178
structure length 444
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 4kjwA00
3NMOA 4MQXA 3EJYA 4KK9A 4KK5A 4KJWA 2H2SA 4FG6A 4KKCA 2FEEA 4KKAA 2HT3A 2FECA 1OTUA 3ORGA 4KJPA 1KPLA 3EJZA 4FTPA 2EXYA 1OTTA 3Q17A 2H2PA 2R9HA 2HT2A 4KJQA 4KKLA 2EXWA 2FEDA 2HLFA 4ENEA 5HD8A 3DETA 1OTSA 4KK6A 1KPKA 2HTLA 3ND0A 4KKBA 4KK8A 4LOUA 2HT4A 2EZ0A 2HTKA
chains in the Genus database with same CATH superfamily
3NMOA 4MQXA 3EJYA 4KK9A 4KK5A 4KJWA 2H2SA 4FG6A 4KKCA 2FEEA 4KKAA 2HT3A 2FECA 1OTUA 3ORGA 4KJPA 1KPLA 3EJZA 4FTPA 2EXYA 1OTTA 3Q17A 2H2PA 2R9HA 2HT2A 4KJQA 4KKLA 2EXWA 2FEDA 2HLFA 4ENEA 5HD8A 3DETA 1OTSA 4KK6A 1KPKA 2HTLA 3ND0A 4KKBA 4KK8A 4LOUA 2HT4A 2EZ0A 2HTKA
chains in the Genus database with same CATH topology
3NMOA 4MQXA 3EJYA 4KK9A 4KK5A 4KJWA 2H2SA 4FG6A 4KKCA 2FEEA 4KKAA 2HT3A 2FECA 1OTUA 3ORGA 4KJPA 1KPLA 3EJZA 4FTPA 2EXYA 1OTTA 3Q17A 2H2PA 2R9HA 2HT2A 4KJQA 4KKLA 2EXWA 2FEDA 2HLFA 4ENEA 5HD8A 3DETA 1OTSA 4KK6A 1KPKA 2HTLA 3ND0A 4KKBA 4KK8A 4LOUA 2HT4A 2EZ0A 2HTKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NMO A;  4MQX A;  3EJY A;  4KK9 A;  4KK5 A;  4KJW A;  2H2S A;  4FG6 A;  4KKC A;  2FEE A;  4KKA A;  2HT3 A;  2FEC A;  1OTU A;  3ORG A;  4KJP A;  1KPL A;  3EJZ A;  4FTP A;  2EXY A;  1OTT A;  3Q17 A;  2H2P A;  2R9H A;  2HT2 A;  4KJQ A;  4KKL A;  2EXW A;  2FED A;  2HLF A;  4ENE A;  5HD8 A;  3DET A;  1OTS A;  4KK6 A;  1KPK A;  2HTL A;  3ND0 A;  4KKB A;  4KK8 A;  4LOU A;  2HT4 A;  2EZ0 A;  2HTK A; 
#chains in the Genus database with same CATH topology
 3NMO A;  4MQX A;  3EJY A;  4KK9 A;  4KK5 A;  4KJW A;  2H2S A;  4FG6 A;  4KKC A;  2FEE A;  4KKA A;  2HT3 A;  2FEC A;  1OTU A;  3ORG A;  4KJP A;  1KPL A;  3EJZ A;  4FTP A;  2EXY A;  1OTT A;  3Q17 A;  2H2P A;  2R9H A;  2HT2 A;  4KJQ A;  4KKL A;  2EXW A;  2FED A;  2HLF A;  4ENE A;  5HD8 A;  3DET A;  1OTS A;  4KK6 A;  1KPK A;  2HTL A;  3ND0 A;  4KKB A;  4KK8 A;  4LOU A;  2HT4 A;  2EZ0 A;  2HTK A; 
#chains in the Genus database with same CATH homology
 3NMO A;  4MQX A;  3EJY A;  4KK9 A;  4KK5 A;  4KJW A;  2H2S A;  4FG6 A;  4KKC A;  2FEE A;  4KKA A;  2HT3 A;  2FEC A;  1OTU A;  3ORG A;  4KJP A;  1KPL A;  3EJZ A;  4FTP A;  2EXY A;  1OTT A;  3Q17 A;  2H2P A;  2R9H A;  2HT2 A;  4KJQ A;  4KKL A;  2EXW A;  2FED A;  2HLF A;  4ENE A;  5HD8 A;  3DET A;  1OTS A;  4KK6 A;  1KPK A;  2HTL A;  3ND0 A;  4KKB A;  4KK8 A;  4LOU A;  2HT4 A;  2EZ0 A;  2HTK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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