1OTTA

Structure of the escherichia coli clc chloride channel e148a mutant and fab complex
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
sequence length
444
structure length
444
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGRAGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Membrane protein
molecule keywords Voltage-gated ClC-type chloride channel eriC
publication title Gating the Selectivity Filter in ClC Chloride Channels
pubmed doi rcsb
source organism Escherichia coli
total genus 169
structure length 444
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 1ottA00
2FEDA 4KKBA 1OTTA 4KKAA 2HLFA 2H2SA 4KK6A 2FECA 3ORGA 3ND0A 4FG6A 2FEEA 4KKLA 5HD8A 2HT3A 4KK9A 4KJPA 4KJWA 3NMOA 4KK8A 2HT4A 4FTPA 3DETA 4KK5A 4ENEA 2HT2A 2H2PA 4LOUA 4KJQA 2HTKA 2EXYA 3EJZA 2EZ0A 2EXWA 1KPKA 2R9HA 1KPLA 4MQXA 3Q17A 1OTSA 4KKCA 2HTLA 1OTUA 3EJYA
chains in the Genus database with same CATH superfamily
2FEDA 4KKBA 1OTTA 4KKAA 2HLFA 2H2SA 4KK6A 2FECA 3ORGA 3ND0A 4FG6A 2FEEA 4KKLA 5HD8A 2HT3A 4KK9A 4KJPA 4KJWA 3NMOA 4KK8A 2HT4A 4FTPA 3DETA 4KK5A 4ENEA 2HT2A 2H2PA 4LOUA 4KJQA 2HTKA 2EXYA 3EJZA 2EZ0A 2EXWA 1KPKA 2R9HA 1KPLA 4MQXA 3Q17A 1OTSA 4KKCA 2HTLA 1OTUA 3EJYA
chains in the Genus database with same CATH topology
2FEDA 4KKBA 1OTTA 4KKAA 2HLFA 2H2SA 4KK6A 2FECA 3ORGA 3ND0A 4FG6A 2FEEA 4KKLA 5HD8A 2HT3A 4KK9A 4KJPA 4KJWA 3NMOA 4KK8A 2HT4A 4FTPA 3DETA 4KK5A 4ENEA 2HT2A 2H2PA 4LOUA 4KJQA 2HTKA 2EXYA 3EJZA 2EZ0A 2EXWA 1KPKA 2R9HA 1KPLA 4MQXA 3Q17A 1OTSA 4KKCA 2HTLA 1OTUA 3EJYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FED A;  4KKB A;  1OTT A;  4KKA A;  2HLF A;  2H2S A;  4KK6 A;  2FEC A;  3ORG A;  3ND0 A;  4FG6 A;  2FEE A;  4KKL A;  5HD8 A;  2HT3 A;  4KK9 A;  4KJP A;  4KJW A;  3NMO A;  4KK8 A;  2HT4 A;  4FTP A;  3DET A;  4KK5 A;  4ENE A;  2HT2 A;  2H2P A;  4LOU A;  4KJQ A;  2HTK A;  2EXY A;  3EJZ A;  2EZ0 A;  2EXW A;  1KPK A;  2R9H A;  1KPL A;  4MQX A;  3Q17 A;  1OTS A;  4KKC A;  2HTL A;  1OTU A;  3EJY A; 
#chains in the Genus database with same CATH topology
 2FED A;  4KKB A;  1OTT A;  4KKA A;  2HLF A;  2H2S A;  4KK6 A;  2FEC A;  3ORG A;  3ND0 A;  4FG6 A;  2FEE A;  4KKL A;  5HD8 A;  2HT3 A;  4KK9 A;  4KJP A;  4KJW A;  3NMO A;  4KK8 A;  2HT4 A;  4FTP A;  3DET A;  4KK5 A;  4ENE A;  2HT2 A;  2H2P A;  4LOU A;  4KJQ A;  2HTK A;  2EXY A;  3EJZ A;  2EZ0 A;  2EXW A;  1KPK A;  2R9H A;  1KPL A;  4MQX A;  3Q17 A;  1OTS A;  4KKC A;  2HTL A;  1OTU A;  3EJY A; 
#chains in the Genus database with same CATH homology
 2FED A;  4KKB A;  1OTT A;  4KKA A;  2HLF A;  2H2S A;  4KK6 A;  2FEC A;  3ORG A;  3ND0 A;  4FG6 A;  2FEE A;  4KKL A;  5HD8 A;  2HT3 A;  4KK9 A;  4KJP A;  4KJW A;  3NMO A;  4KK8 A;  2HT4 A;  4FTP A;  3DET A;  4KK5 A;  4ENE A;  2HT2 A;  2H2P A;  4LOU A;  4KJQ A;  2HTK A;  2EXY A;  3EJZ A;  2EZ0 A;  2EXW A;  1KPK A;  2R9H A;  1KPL A;  4MQX A;  3Q17 A;  1OTS A;  4KKC A;  2HTL A;  1OTU A;  3EJY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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