4KKLA

Structure of the e148a mutant of clc-ec1 delta nc construct in 100mm fluoride
Total Genus 177
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
177
sequence length
444
structure length
444
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGRAGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Tranport protein, membrane protein
molecule keywords H(+)/Cl(-) exchange transporter ClcA
publication title Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
pubmed doi rcsb
source organism Escherichia coli
total genus 177
structure length 444
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 4kklA00
3ORGA 2FEEA 2EXWA 1OTUA 3Q17A 4KK9A 4KKLA 2FEDA 5HD8A 3EJZA 2HLFA 3ND0A 4KJWA 2EZ0A 2R9HA 2HTLA 4KKAA 2HT4A 4ENEA 2FECA 3NMOA 3DETA 4KK6A 4KKCA 4KJQA 1KPLA 4LOUA 2HT2A 4MQXA 1OTTA 4KKBA 4FTPA 2EXYA 2H2SA 4KK8A 2H2PA 4KK5A 3EJYA 4FG6A 4KJPA 1KPKA 2HT3A 1OTSA 2HTKA
chains in the Genus database with same CATH superfamily
3ORGA 2FEEA 2EXWA 1OTUA 3Q17A 4KK9A 4KKLA 2FEDA 5HD8A 3EJZA 2HLFA 3ND0A 4KJWA 2EZ0A 2R9HA 2HTLA 4KKAA 2HT4A 4ENEA 2FECA 3NMOA 3DETA 4KK6A 4KKCA 4KJQA 1KPLA 4LOUA 2HT2A 4MQXA 1OTTA 4KKBA 4FTPA 2EXYA 2H2SA 4KK8A 2H2PA 4KK5A 3EJYA 4FG6A 4KJPA 1KPKA 2HT3A 1OTSA 2HTKA
chains in the Genus database with same CATH topology
3ORGA 2FEEA 2EXWA 1OTUA 3Q17A 4KK9A 4KKLA 2FEDA 5HD8A 3EJZA 2HLFA 3ND0A 4KJWA 2EZ0A 2R9HA 2HTLA 4KKAA 2HT4A 4ENEA 2FECA 3NMOA 3DETA 4KK6A 4KKCA 4KJQA 1KPLA 4LOUA 2HT2A 4MQXA 1OTTA 4KKBA 4FTPA 2EXYA 2H2SA 4KK8A 2H2PA 4KK5A 3EJYA 4FG6A 4KJPA 1KPKA 2HT3A 1OTSA 2HTKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ORG A;  2FEE A;  2EXW A;  1OTU A;  3Q17 A;  4KK9 A;  4KKL A;  2FED A;  5HD8 A;  3EJZ A;  2HLF A;  3ND0 A;  4KJW A;  2EZ0 A;  2R9H A;  2HTL A;  4KKA A;  2HT4 A;  4ENE A;  2FEC A;  3NMO A;  3DET A;  4KK6 A;  4KKC A;  4KJQ A;  1KPL A;  4LOU A;  2HT2 A;  4MQX A;  1OTT A;  4KKB A;  4FTP A;  2EXY A;  2H2S A;  4KK8 A;  2H2P A;  4KK5 A;  3EJY A;  4FG6 A;  4KJP A;  1KPK A;  2HT3 A;  1OTS A;  2HTK A; 
#chains in the Genus database with same CATH topology
 3ORG A;  2FEE A;  2EXW A;  1OTU A;  3Q17 A;  4KK9 A;  4KKL A;  2FED A;  5HD8 A;  3EJZ A;  2HLF A;  3ND0 A;  4KJW A;  2EZ0 A;  2R9H A;  2HTL A;  4KKA A;  2HT4 A;  4ENE A;  2FEC A;  3NMO A;  3DET A;  4KK6 A;  4KKC A;  4KJQ A;  1KPL A;  4LOU A;  2HT2 A;  4MQX A;  1OTT A;  4KKB A;  4FTP A;  2EXY A;  2H2S A;  4KK8 A;  2H2P A;  4KK5 A;  3EJY A;  4FG6 A;  4KJP A;  1KPK A;  2HT3 A;  1OTS A;  2HTK A; 
#chains in the Genus database with same CATH homology
 3ORG A;  2FEE A;  2EXW A;  1OTU A;  3Q17 A;  4KK9 A;  4KKL A;  2FED A;  5HD8 A;  3EJZ A;  2HLF A;  3ND0 A;  4KJW A;  2EZ0 A;  2R9H A;  2HTL A;  4KKA A;  2HT4 A;  4ENE A;  2FEC A;  3NMO A;  3DET A;  4KK6 A;  4KKC A;  4KJQ A;  1KPL A;  4LOU A;  2HT2 A;  4MQX A;  1OTT A;  4KKB A;  4FTP A;  2EXY A;  2H2S A;  4KK8 A;  2H2P A;  4KK5 A;  3EJY A;  4FG6 A;  4KJP A;  1KPK A;  2HT3 A;  1OTS A;  2HTK A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...