1KPLA

Crystal structure of the clc chloride channel from s. typhimurium
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
430
structure length
430
Chain Sequence
TPLAILFMAAVVGTLTGLVGVAFEKAVSWVQNMRIGALVQVADHAFLLWPLAFILSALLAMVGYFLVRKFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFRMRSAEARHTLLATGAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFRIFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGVVGPVFNSLVLRTQDMFQRFHGGEIKKWVLMGGAIGGLCGILGLIEPAAAGGGFNLIPIAAAGNFSVGLLLFIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFPQYHLEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILARTLAKQDAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Membrane protein
molecule keywords putative ClC family, chlorine transport protein
publication title X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
pubmed doi rcsb
source organism Salmonella typhimurium
total genus 166
structure length 430
sequence length 430
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2001-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 1kplA00
1OTUA 4KJPA 1KPKA 3ND0A 2EZ0A 4KKAA 4KKLA 4KJQA 2FECA 4KK8A 2R9HA 4KK5A 2EXWA 4FG6A 2HT4A 2HT2A 4KKBA 2HT3A 1OTSA 2FEEA 3NMOA 4MQXA 2FEDA 2H2SA 1OTTA 3DETA 4KK9A 2EXYA 4LOUA 5HD8A 4ENEA 2HTKA 4KKCA 4FTPA 2H2PA 3EJYA 2HTLA 3Q17A 4KK6A 2HLFA 3EJZA 1KPLA 3ORGA 4KJWA
chains in the Genus database with same CATH superfamily
1OTUA 4KJPA 1KPKA 3ND0A 2EZ0A 4KKAA 4KKLA 4KJQA 2FECA 4KK8A 2R9HA 4KK5A 2EXWA 4FG6A 2HT4A 2HT2A 4KKBA 2HT3A 1OTSA 2FEEA 3NMOA 4MQXA 2FEDA 2H2SA 1OTTA 3DETA 4KK9A 2EXYA 4LOUA 5HD8A 4ENEA 2HTKA 4KKCA 4FTPA 2H2PA 3EJYA 2HTLA 3Q17A 4KK6A 2HLFA 3EJZA 1KPLA 3ORGA 4KJWA
chains in the Genus database with same CATH topology
1OTUA 4KJPA 1KPKA 3ND0A 2EZ0A 4KKAA 4KKLA 4KJQA 2FECA 4KK8A 2R9HA 4KK5A 2EXWA 4FG6A 2HT4A 2HT2A 4KKBA 2HT3A 1OTSA 2FEEA 3NMOA 4MQXA 2FEDA 2H2SA 1OTTA 3DETA 4KK9A 2EXYA 4LOUA 5HD8A 4ENEA 2HTKA 4KKCA 4FTPA 2H2PA 3EJYA 2HTLA 3Q17A 4KK6A 2HLFA 3EJZA 1KPLA 3ORGA 4KJWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OTU A;  4KJP A;  1KPK A;  3ND0 A;  2EZ0 A;  4KKA A;  4KKL A;  4KJQ A;  2FEC A;  4KK8 A;  2R9H A;  4KK5 A;  2EXW A;  4FG6 A;  2HT4 A;  2HT2 A;  4KKB A;  2HT3 A;  1OTS A;  2FEE A;  3NMO A;  4MQX A;  2FED A;  2H2S A;  1OTT A;  3DET A;  4KK9 A;  2EXY A;  4LOU A;  5HD8 A;  4ENE A;  2HTK A;  4KKC A;  4FTP A;  2H2P A;  3EJY A;  2HTL A;  3Q17 A;  4KK6 A;  2HLF A;  3EJZ A;  1KPL A;  3ORG A;  4KJW A; 
#chains in the Genus database with same CATH topology
 1OTU A;  4KJP A;  1KPK A;  3ND0 A;  2EZ0 A;  4KKA A;  4KKL A;  4KJQ A;  2FEC A;  4KK8 A;  2R9H A;  4KK5 A;  2EXW A;  4FG6 A;  2HT4 A;  2HT2 A;  4KKB A;  2HT3 A;  1OTS A;  2FEE A;  3NMO A;  4MQX A;  2FED A;  2H2S A;  1OTT A;  3DET A;  4KK9 A;  2EXY A;  4LOU A;  5HD8 A;  4ENE A;  2HTK A;  4KKC A;  4FTP A;  2H2P A;  3EJY A;  2HTL A;  3Q17 A;  4KK6 A;  2HLF A;  3EJZ A;  1KPL A;  3ORG A;  4KJW A; 
#chains in the Genus database with same CATH homology
 1OTU A;  4KJP A;  1KPK A;  3ND0 A;  2EZ0 A;  4KKA A;  4KKL A;  4KJQ A;  2FEC A;  4KK8 A;  2R9H A;  4KK5 A;  2EXW A;  4FG6 A;  2HT4 A;  2HT2 A;  4KKB A;  2HT3 A;  1OTS A;  2FEE A;  3NMO A;  4MQX A;  2FED A;  2H2S A;  1OTT A;  3DET A;  4KK9 A;  2EXY A;  4LOU A;  5HD8 A;  4ENE A;  2HTK A;  4KKC A;  4FTP A;  2H2P A;  3EJY A;  2HTL A;  3Q17 A;  4KK6 A;  2HLF A;  3EJZ A;  1KPL A;  3ORG A;  4KJW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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