1O4XB

Ternary complex of the dna binding domains of the oct1 and sox2 transcription factors with a 19mer oligonucleotide from the hoxb1 regulatory element
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
77
structure length
77
Chain Sequence
DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*
total genus 20
structure length 77
sequence length 77
ec nomenclature
pdb deposition date 2003-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00505 HMG_box HMG (high mobility group) box
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.30.10 Mainly Alpha Orthogonal Bundle DNA Binding (I), subunit A High mobility group box domain 1o4xB00
1HSNA 2LEFA 1HSMA 1WXLA 2CRJA 2EQZA 2YQIA 3FGHA 1V63A 1WGFA 3TQ6A 1WZ6A 2YULA 1J46A 2YRQA 4Y60C 1CG7A 4S2QD 1HMEA 2LE4A 3NM9A 1CKTA 4NODA 1J47A 1LWMA 1GT0D 2YUKA 2RTUA 1V64A 1J5NA 1HRZA 2GZKA 2HDZA 1J3DA 2CS1A 4QR9A 2D7LA 1QRVA 4EUWA 1HMFA 1HMAA 4A3NA 3F27D 3TMMA 1E7JA 4NNUA 1AABA 1K99A 1L8ZA 1NHNA 2CTOA 1O4XB 1I11A 2CO9A 1NHMA 1J3XA 3U2BC 1L8YA 2LY4A 2LHJA 1J3CA 1HRYA 2E6OA
chains in the Genus database with same CATH superfamily
1HSNA 2LEFA 1HSMA 1WXLA 2CRJA 2EQZA 2YQIA 3ABRB 3ANYB 1V63A 1WGFA 3AO0B 3FGHA 3TQ6A 1WZ6A 2YULA 4A15A 1J46A 2YRQA 4Y60C 1CG7A 4S2QD 1HMEA 2LE4A 3NM9A 1CKTA 4KQEA 4NODA 1J47A 1LWMA 1GT0D 2YUKA 2RTUA 1V64A 1J5NA 1HRZA 2GZKA 2HDZA 1J3DA 2CS1A 4QR9A 2D7LA 1QRVA 4EUWA 1HMFA 1HMAA 4A3NA 3F27D 3TMMA 1E7JA 3ABOB 4NNUA 1AABA 1K99A 1L8ZA 1NHNA 2CTOA 1O4XB 1I11A 2CO9A 1NHMA 1J3XA 3U2BC 1L8YA 3ABSB 2LY4A 2VSFA 2LHJA 1J3CA 1HRYA 5H8WA 2E6OA
chains in the Genus database with same CATH topology
1HSNA 2LEFA 1HSMA 1WXLA 2CRJA 2EQZA 2YQIA 3FGHA 1V63A 1WGFA 3TQ6A 1WZ6A 2YULA 1J46A 2YRQA 4Y60C 1CG7A 4S2QD 1HMEA 2LE4A 3NM9A 1CKTA 4NODA 1J47A 1LWMA 1GT0D 2YUKA 2RTUA 1V64A 1J5NA 1HRZA 2GZKA 2HDZA 1J3DA 2CS1A 4QR9A 2D7LA 1QRVA 4EUWA 1HMFA 1HMAA 4A3NA 3F27D 3TMMA 1E7JA 4NNUA 1AABA 1K99A 1L8ZA 1NHNA 2CTOA 1O4XB 1I11A 2CO9A 1NHMA 1J3XA 3U2BC 1L8YA 2LY4A 2LHJA 1J3CA 1HRYA 2E6OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HSN A;  2LEF A;  1HSM A;  1WXL A;  2CRJ A;  2EQZ A;  2YQI A;  3FGH A;  1V63 A;  1WGF A;  3TQ6 A;  1WZ6 A;  2YUL A;  1J46 A;  2YRQ A;  4Y60 C;  1CG7 A;  4S2Q D;  1HME A;  2LE4 A;  3NM9 A;  1CKT A;  4NOD A;  1J47 A;  1LWM A;  1GT0 D;  2YUK A;  2RTU A;  1V64 A;  1J5N A;  1HRZ A;  2GZK A;  2HDZ A;  1J3D A;  2CS1 A;  4QR9 A;  2D7L A;  1QRV A;  4EUW A;  1HMF A;  1HMA A;  4A3N A;  3F27 D;  3TMM A;  1E7J A;  4NNU A;  1AAB A;  1K99 A;  1L8Z A;  1NHN A;  2CTO A;  1O4X B;  1I11 A;  2CO9 A;  1NHM A;  1J3X A;  3U2B C;  1L8Y A;  2LY4 A;  2LHJ A;  1J3C A;  1HRY A;  2E6O A; 
#chains in the Genus database with same CATH topology
 1HSN A;  2LEF A;  1HSM A;  1WXL A;  2CRJ A;  2EQZ A;  2YQI A;  3ABR B;  3ANY B;  1V63 A;  1WGF A;  3AO0 B;  3FGH A;  3TQ6 A;  1WZ6 A;  2YUL A;  4A15 A;  1J46 A;  2YRQ A;  4Y60 C;  1CG7 A;  4S2Q D;  1HME A;  2LE4 A;  3NM9 A;  1CKT A;  4KQE A;  4NOD A;  1J47 A;  1LWM A;  1GT0 D;  2YUK A;  2RTU A;  1V64 A;  1J5N A;  1HRZ A;  2GZK A;  2HDZ A;  1J3D A;  2CS1 A;  4QR9 A;  2D7L A;  1QRV A;  4EUW A;  1HMF A;  1HMA A;  4A3N A;  3F27 D;  3TMM A;  1E7J A;  3ABO B;  4NNU A;  1AAB A;  1K99 A;  1L8Z A;  1NHN A;  2CTO A;  1O4X B;  1I11 A;  2CO9 A;  1NHM A;  1J3X A;  3U2B C;  1L8Y A;  3ABS B;  2LY4 A;  2VSF A;  2LHJ A;  1J3C A;  1HRY A;  5H8W A;  2E6O A; 
#chains in the Genus database with same CATH homology
 1HSN A;  2LEF A;  1HSM A;  1WXL A;  2CRJ A;  2EQZ A;  2YQI A;  3FGH A;  1V63 A;  1WGF A;  3TQ6 A;  1WZ6 A;  2YUL A;  1J46 A;  2YRQ A;  4Y60 C;  1CG7 A;  4S2Q D;  1HME A;  2LE4 A;  3NM9 A;  1CKT A;  4NOD A;  1J47 A;  1LWM A;  1GT0 D;  2YUK A;  2RTU A;  1V64 A;  1J5N A;  1HRZ A;  2GZK A;  2HDZ A;  1J3D A;  2CS1 A;  4QR9 A;  2D7L A;  1QRV A;  4EUW A;  1HMF A;  1HMA A;  4A3N A;  3F27 D;  3TMM A;  1E7J A;  4NNU A;  1AAB A;  1K99 A;  1L8Z A;  1NHN A;  2CTO A;  1O4X B;  1I11 A;  2CO9 A;  1NHM A;  1J3X A;  3U2B C;  1L8Y A;  2LY4 A;  2LHJ A;  1J3C A;  1HRY A;  2E6O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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