1OTTA

Structure of the escherichia coli clc chloride channel e148a mutant and fab complex
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
sequence length
444
structure length
444
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGRAGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Gating the Selectivity Filter in ClC Chloride Channels
pubmed doi rcsb
molecule keywords Voltage-gated ClC-type chloride channel eriC
molecule tags Membrane protein
source organism Escherichia coli
total genus 169
structure length 444
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 1ottA00
1OTTA 4KJWA 3Q17A 3DETA 1OTUA 4KKBA 4LOUA 2EXWA 2H2SA 1KPLA 3NMOA 4FTPA 2R9HA 2HT2A 4KK6A 2H2PA 4KJPA 5HD8A 2HT4A 3ORGA 2FECA 3ND0A 3EJYA 4KKAA 1KPKA 4KJQA 2HTLA 4KKLA 3EJZA 4KK8A 4KK5A 2EZ0A 4MQXA 4ENEA 2FEDA 1OTSA 2HLFA 4KKCA 2HT3A 4KK9A 2FEEA 2EXYA 2HTKA 4FG6A
chains in the Genus database with same CATH superfamily
1OTTA 4KJWA 3Q17A 3DETA 1OTUA 4KKBA 4LOUA 2EXWA 2H2SA 1KPLA 3NMOA 4FTPA 2R9HA 2HT2A 4KK6A 2H2PA 4KJPA 5HD8A 2HT4A 3ORGA 2FECA 3ND0A 3EJYA 4KKAA 1KPKA 4KJQA 2HTLA 4KKLA 3EJZA 4KK8A 4KK5A 2EZ0A 4MQXA 4ENEA 2FEDA 1OTSA 2HLFA 4KKCA 2HT3A 4KK9A 2FEEA 2EXYA 2HTKA 4FG6A
chains in the Genus database with same CATH topology
1OTTA 4KJWA 3Q17A 3DETA 1OTUA 4KKBA 4LOUA 2EXWA 2H2SA 1KPLA 3NMOA 4FTPA 2R9HA 2HT2A 4KK6A 2H2PA 4KJPA 5HD8A 2HT4A 3ORGA 2FECA 3ND0A 3EJYA 4KKAA 1KPKA 4KJQA 2HTLA 4KKLA 3EJZA 4KK8A 4KK5A 2EZ0A 4MQXA 4ENEA 2FEDA 1OTSA 2HLFA 4KKCA 2HT3A 4KK9A 2FEEA 2EXYA 2HTKA 4FG6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OTT A;  4KJW A;  3Q17 A;  3DET A;  1OTU A;  4KKB A;  4LOU A;  2EXW A;  2H2S A;  1KPL A;  3NMO A;  4FTP A;  2R9H A;  2HT2 A;  4KK6 A;  2H2P A;  4KJP A;  5HD8 A;  2HT4 A;  3ORG A;  2FEC A;  3ND0 A;  3EJY A;  4KKA A;  1KPK A;  4KJQ A;  2HTL A;  4KKL A;  3EJZ A;  4KK8 A;  4KK5 A;  2EZ0 A;  4MQX A;  4ENE A;  2FED A;  1OTS A;  2HLF A;  4KKC A;  2HT3 A;  4KK9 A;  2FEE A;  2EXY A;  2HTK A;  4FG6 A; 
#chains in the Genus database with same CATH topology
 1OTT A;  4KJW A;  3Q17 A;  3DET A;  1OTU A;  4KKB A;  4LOU A;  2EXW A;  2H2S A;  1KPL A;  3NMO A;  4FTP A;  2R9H A;  2HT2 A;  4KK6 A;  2H2P A;  4KJP A;  5HD8 A;  2HT4 A;  3ORG A;  2FEC A;  3ND0 A;  3EJY A;  4KKA A;  1KPK A;  4KJQ A;  2HTL A;  4KKL A;  3EJZ A;  4KK8 A;  4KK5 A;  2EZ0 A;  4MQX A;  4ENE A;  2FED A;  1OTS A;  2HLF A;  4KKC A;  2HT3 A;  4KK9 A;  2FEE A;  2EXY A;  2HTK A;  4FG6 A; 
#chains in the Genus database with same CATH homology
 1OTT A;  4KJW A;  3Q17 A;  3DET A;  1OTU A;  4KKB A;  4LOU A;  2EXW A;  2H2S A;  1KPL A;  3NMO A;  4FTP A;  2R9H A;  2HT2 A;  4KK6 A;  2H2P A;  4KJP A;  5HD8 A;  2HT4 A;  3ORG A;  2FEC A;  3ND0 A;  3EJY A;  4KKA A;  1KPK A;  4KJQ A;  2HTL A;  4KKL A;  3EJZ A;  4KK8 A;  4KK5 A;  2EZ0 A;  4MQX A;  4ENE A;  2FED A;  1OTS A;  2HLF A;  4KKC A;  2HT3 A;  4KK9 A;  2FEE A;  2EXY A;  2HTK A;  4FG6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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