1OTUA

Structure of the escherichia coli clc chloride channel e148q mutant and fab complex
Total Genus 154
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
154
sequence length
444
structure length
444
Chain Sequence
RRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGRQGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Gating the Selectivity Filter in ClC Chloride Channels
pubmed doi rcsb
molecule tags Membrane protein
source organism Escherichia coli
molecule keywords Voltage-gated ClC-type chloride channel eriC
total genus 154
structure length 444
sequence length 444
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00654 Voltage_CLC Voltage gated chloride channel
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3080.10 Mainly Alpha Orthogonal Bundle Clc chloride channel Clc chloride channel 1otuA00
3EJZA 2FEDA 2EZ0A 2FECA 1KPLA 3ORGA 4KKCA 3EJYA 4KJPA 4KK8A 2HT2A 4KJWA 3DETA 4KKLA 2R9HA 2HTKA 1OTSA 4KKAA 4FTPA 4FG6A 4KJQA 2H2SA 4KK5A 2HT3A 2EXWA 1OTUA 2HT4A 4LOUA 4ENEA 4KK6A 3ND0A 4KKBA 4MQXA 2EXYA 5HD8A 2FEEA 1KPKA 2HTLA 1OTTA 3NMOA 3Q17A 4KK9A 2HLFA 2H2PA
chains in the Genus database with same CATH superfamily
3EJZA 2FEDA 2EZ0A 2FECA 1KPLA 3ORGA 4KKCA 3EJYA 4KJPA 4KK8A 2HT2A 4KJWA 3DETA 4KKLA 2R9HA 2HTKA 1OTSA 4KKAA 4FTPA 4FG6A 4KJQA 2H2SA 4KK5A 2HT3A 2EXWA 1OTUA 2HT4A 4LOUA 4ENEA 4KK6A 3ND0A 4KKBA 4MQXA 2EXYA 5HD8A 2FEEA 1KPKA 2HTLA 1OTTA 3NMOA 3Q17A 4KK9A 2HLFA 2H2PA
chains in the Genus database with same CATH topology
3EJZA 2FEDA 2EZ0A 2FECA 1KPLA 3ORGA 4KKCA 3EJYA 4KJPA 4KK8A 2HT2A 4KJWA 3DETA 4KKLA 2R9HA 2HTKA 1OTSA 4KKAA 4FTPA 4FG6A 4KJQA 2H2SA 4KK5A 2HT3A 2EXWA 1OTUA 2HT4A 4LOUA 4ENEA 4KK6A 3ND0A 4KKBA 4MQXA 2EXYA 5HD8A 2FEEA 1KPKA 2HTLA 1OTTA 3NMOA 3Q17A 4KK9A 2HLFA 2H2PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EJZ A;  2FED A;  2EZ0 A;  2FEC A;  1KPL A;  3ORG A;  4KKC A;  3EJY A;  4KJP A;  4KK8 A;  2HT2 A;  4KJW A;  3DET A;  4KKL A;  2R9H A;  2HTK A;  1OTS A;  4KKA A;  4FTP A;  4FG6 A;  4KJQ A;  2H2S A;  4KK5 A;  2HT3 A;  2EXW A;  1OTU A;  2HT4 A;  4LOU A;  4ENE A;  4KK6 A;  3ND0 A;  4KKB A;  4MQX A;  2EXY A;  5HD8 A;  2FEE A;  1KPK A;  2HTL A;  1OTT A;  3NMO A;  3Q17 A;  4KK9 A;  2HLF A;  2H2P A; 
#chains in the Genus database with same CATH topology
 3EJZ A;  2FED A;  2EZ0 A;  2FEC A;  1KPL A;  3ORG A;  4KKC A;  3EJY A;  4KJP A;  4KK8 A;  2HT2 A;  4KJW A;  3DET A;  4KKL A;  2R9H A;  2HTK A;  1OTS A;  4KKA A;  4FTP A;  4FG6 A;  4KJQ A;  2H2S A;  4KK5 A;  2HT3 A;  2EXW A;  1OTU A;  2HT4 A;  4LOU A;  4ENE A;  4KK6 A;  3ND0 A;  4KKB A;  4MQX A;  2EXY A;  5HD8 A;  2FEE A;  1KPK A;  2HTL A;  1OTT A;  3NMO A;  3Q17 A;  4KK9 A;  2HLF A;  2H2P A; 
#chains in the Genus database with same CATH homology
 3EJZ A;  2FED A;  2EZ0 A;  2FEC A;  1KPL A;  3ORG A;  4KKC A;  3EJY A;  4KJP A;  4KK8 A;  2HT2 A;  4KJW A;  3DET A;  4KKL A;  2R9H A;  2HTK A;  1OTS A;  4KKA A;  4FTP A;  4FG6 A;  4KJQ A;  2H2S A;  4KK5 A;  2HT3 A;  2EXW A;  1OTU A;  2HT4 A;  4LOU A;  4ENE A;  4KK6 A;  3ND0 A;  4KKB A;  4MQX A;  2EXY A;  5HD8 A;  2FEE A;  1KPK A;  2HTL A;  1OTT A;  3NMO A;  3Q17 A;  4KK9 A;  2HLF A;  2H2P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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