1OW3 | Genus

Total Genus 70

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	70
sequence length	196
structure length	196
Chain Sequence	PLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 196 atoms

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196 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer pubmed doi rcsb
molecule keywords	Rho-GTPase-activating protein 1
molecule tags	Gene regulation/signaling protein
source organism	Homo sapiens
total genus	70
structure length	196
sequence length	196
ec nomenclature
pdb deposition date	2003-03-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00620	RhoGAP	RhoGAP domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.555.10	Mainly Alpha	Orthogonal Bundle	Phosphatidylinositol 3-kinase; Chain A	Rho GTPase activation protein	1ow3A00

1XA6A 3WPSA 3QISA 5JCPA 2XS6A 5C2JA 5HPYA 3MSXB 2EE5A 3WPQA 2EE4A 3EAPA 1OW3A 3KUQA 1GRNB 2OSAA 5C5SA 2QV2A 1RGPA 1AM4A 3FK2A 5IRCA 2MBGA 2NGRB 1PBWA 3W6RA 3IUGA 5JD0A 2OVJA 3CXLA 1TX4A 3BYIA 1F7CA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1XA6 A;  3WPS A;  3QIS A;  5JCP A;  2XS6 A;  5C2J A;  5HPY A;  3MSX B;  2EE5 A;  3WPQ A;  2EE4 A;  3EAP A;  1OW3 A;  3KUQ A;  1GRN B;  2OSA A;  5C5S A;  2QV2 A;  1RGP A;  1AM4 A;  3FK2 A;  5IRC A;  2MBG A;  2NGR B;  1PBW A;  3W6R A;  3IUG A;  5JD0 A;  2OVJ A;  3CXL A;  1TX4 A;  3BYI A;  1F7C A; 
#chains in the Genus database with same CATH topology
 1XA6 A;  3WPS A;  3QIS A;  5JCP A;  2XS6 A;  5C2J A;  5HPY A;  3MSX B;  2EE5 A;  3WPQ A;  2EE4 A;  3EAP A;  1OW3 A;  3KUQ A;  1GRN B;  2OSA A;  5C5S A;  2QV2 A;  1RGP A;  1AM4 A;  3FK2 A;  5IRC A;  2MBG A;  2NGR B;  1PBW A;  3W6R A;  3IUG A;  5JD0 A;  2OVJ A;  3CXL A;  1TX4 A;  3BYI A;  1F7C A; 
#chains in the Genus database with same CATH homology
 1XA6 A;  3WPS A;  3QIS A;  5JCP A;  2XS6 A;  5C2J A;  5HPY A;  3MSX B;  2EE5 A;  3WPQ A;  2EE4 A;  3EAP A;  1OW3 A;  3KUQ A;  1GRN B;  2OSA A;  5C5S A;  2QV2 A;  1RGP A;  1AM4 A;  3FK2 A;  5IRC A;  2MBG A;  2NGR B;  1PBW A;  3W6R A;  3IUG A;  5JD0 A;  2OVJ A;  3CXL A;  1TX4 A;  3BYI A;  1F7C A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1OW3A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations