1PBWA

Structure of bcr-homology (bh) domain
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
184
structure length
184
Chain Sequence
LPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit.
pubmed doi rcsb
molecule keywords PHOSPHATIDYLINOSITOL 3-KINASE
molecule tags Phosphotransferase
source organism Homo sapiens
total genus 67
structure length 184
sequence length 184
chains with identical sequence B
ec nomenclature
pdb deposition date 1996-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1pbwA00
1TX4A 3QISA 5IRCA 2EE4A 1RGPA 1XA6A 2NGRB 3W6RA 1F7CA 5JCPA 5JD0A 2OSAA 5HPYA 5C5SA 1OW3A 1GRNB 3WPSA 3KUQA 3BYIA 2QV2A 3FK2A 1PBWA 3IUGA 3WPQA 3EAPA 3MSXB 2OVJA 3CXLA 5C2JA 1AM4A 2XS6A 2EE5A 2MBGA
chains in the Genus database with same CATH superfamily
1TX4A 3QISA 5IRCA 2EE4A 1RGPA 1XA6A 2NGRB 3W6RA 1F7CA 5JCPA 5JD0A 2OSAA 5HPYA 5C5SA 1OW3A 1GRNB 3WPSA 3KUQA 3BYIA 2QV2A 3FK2A 1PBWA 3IUGA 3WPQA 3EAPA 3MSXB 2OVJA 3CXLA 5C2JA 1AM4A 2XS6A 2EE5A 2MBGA
chains in the Genus database with same CATH topology
1TX4A 3QISA 5IRCA 2EE4A 1RGPA 1XA6A 2NGRB 3W6RA 1F7CA 5JCPA 5JD0A 2OSAA 5HPYA 5C5SA 1OW3A 1GRNB 3WPSA 3KUQA 3BYIA 2QV2A 3FK2A 1PBWA 3IUGA 3WPQA 3EAPA 3MSXB 2OVJA 3CXLA 5C2JA 1AM4A 2XS6A 2EE5A 2MBGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TX4 A;  3QIS A;  5IRC A;  2EE4 A;  1RGP A;  1XA6 A;  2NGR B;  3W6R A;  1F7C A;  5JCP A;  5JD0 A;  2OSA A;  5HPY A;  5C5S A;  1OW3 A;  1GRN B;  3WPS A;  3KUQ A;  3BYI A;  2QV2 A;  3FK2 A;  1PBW A;  3IUG A;  3WPQ A;  3EAP A;  3MSX B;  2OVJ A;  3CXL A;  5C2J A;  1AM4 A;  2XS6 A;  2EE5 A;  2MBG A; 
#chains in the Genus database with same CATH topology
 1TX4 A;  3QIS A;  5IRC A;  2EE4 A;  1RGP A;  1XA6 A;  2NGR B;  3W6R A;  1F7C A;  5JCP A;  5JD0 A;  2OSA A;  5HPY A;  5C5S A;  1OW3 A;  1GRN B;  3WPS A;  3KUQ A;  3BYI A;  2QV2 A;  3FK2 A;  1PBW A;  3IUG A;  3WPQ A;  3EAP A;  3MSX B;  2OVJ A;  3CXL A;  5C2J A;  1AM4 A;  2XS6 A;  2EE5 A;  2MBG A; 
#chains in the Genus database with same CATH homology
 1TX4 A;  3QIS A;  5IRC A;  2EE4 A;  1RGP A;  1XA6 A;  2NGR B;  3W6R A;  1F7C A;  5JCP A;  5JD0 A;  2OSA A;  5HPY A;  5C5S A;  1OW3 A;  1GRN B;  3WPS A;  3KUQ A;  3BYI A;  2QV2 A;  3FK2 A;  1PBW A;  3IUG A;  3WPQ A;  3EAP A;  3MSX B;  2OVJ A;  3CXL A;  5C2J A;  1AM4 A;  2XS6 A;  2EE5 A;  2MBG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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