1PBWA

Structure of bcr-homology (bh) domain
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
184
structure length
184
Chain Sequence
LPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit.
pubmed doi rcsb
molecule tags Phosphotransferase
source organism Homo sapiens
molecule keywords PHOSPHATIDYLINOSITOL 3-KINASE
total genus 67
structure length 184
sequence length 184
chains with identical sequence B
ec nomenclature
pdb deposition date 1996-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1pbwA00
5HPYA 1PBWA 3W6RA 3IUGA 3BYIA 1TX4A 2EE5A 2MBGA 5JCPA 1F7CA 2OSAA 1GRNB 3EAPA 2EE4A 1AM4A 2NGRB 3MSXB 1RGPA 3QISA 1OW3A 2XS6A 5IRCA 3FK2A 5C5SA 3WPQA 3KUQA 3WPSA 5JD0A 1XA6A 2QV2A 3CXLA 2OVJA 5C2JA
chains in the Genus database with same CATH superfamily
5HPYA 1PBWA 3W6RA 3IUGA 3BYIA 1TX4A 2EE5A 2MBGA 5JCPA 1F7CA 2OSAA 1GRNB 3EAPA 2EE4A 1AM4A 2NGRB 3MSXB 1RGPA 3QISA 1OW3A 2XS6A 5IRCA 3FK2A 5C5SA 3WPQA 3KUQA 3WPSA 5JD0A 1XA6A 2QV2A 3CXLA 2OVJA 5C2JA
chains in the Genus database with same CATH topology
5HPYA 1PBWA 3W6RA 3IUGA 3BYIA 1TX4A 2EE5A 2MBGA 5JCPA 1F7CA 2OSAA 1GRNB 3EAPA 2EE4A 1AM4A 2NGRB 3MSXB 1RGPA 3QISA 1OW3A 2XS6A 5IRCA 3FK2A 5C5SA 3WPQA 3KUQA 3WPSA 5JD0A 1XA6A 2QV2A 3CXLA 2OVJA 5C2JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HPY A;  1PBW A;  3W6R A;  3IUG A;  3BYI A;  1TX4 A;  2EE5 A;  2MBG A;  5JCP A;  1F7C A;  2OSA A;  1GRN B;  3EAP A;  2EE4 A;  1AM4 A;  2NGR B;  3MSX B;  1RGP A;  3QIS A;  1OW3 A;  2XS6 A;  5IRC A;  3FK2 A;  5C5S A;  3WPQ A;  3KUQ A;  3WPS A;  5JD0 A;  1XA6 A;  2QV2 A;  3CXL A;  2OVJ A;  5C2J A; 
#chains in the Genus database with same CATH topology
 5HPY A;  1PBW A;  3W6R A;  3IUG A;  3BYI A;  1TX4 A;  2EE5 A;  2MBG A;  5JCP A;  1F7C A;  2OSA A;  1GRN B;  3EAP A;  2EE4 A;  1AM4 A;  2NGR B;  3MSX B;  1RGP A;  3QIS A;  1OW3 A;  2XS6 A;  5IRC A;  3FK2 A;  5C5S A;  3WPQ A;  3KUQ A;  3WPS A;  5JD0 A;  1XA6 A;  2QV2 A;  3CXL A;  2OVJ A;  5C2J A; 
#chains in the Genus database with same CATH homology
 5HPY A;  1PBW A;  3W6R A;  3IUG A;  3BYI A;  1TX4 A;  2EE5 A;  2MBG A;  5JCP A;  1F7C A;  2OSA A;  1GRN B;  3EAP A;  2EE4 A;  1AM4 A;  2NGR B;  3MSX B;  1RGP A;  3QIS A;  1OW3 A;  2XS6 A;  5IRC A;  3FK2 A;  5C5S A;  3WPQ A;  3KUQ A;  3WPS A;  5JD0 A;  1XA6 A;  2QV2 A;  3CXL A;  2OVJ A;  5C2J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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