1RGPA

Gtpase-activation domain from rhogap
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
199
structure length
189
Chain Sequence
PRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWINPINTFTKFLLDHQGELF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of the GTPase-activating domain from p50rhoGAP.
pubmed doi rcsb
molecule keywords RHOGAP
molecule tags G-protein
source organism Homo sapiens
total genus 61
structure length 189
sequence length 199
ec nomenclature
pdb deposition date 1996-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1rgpA00
3W6RA 1F7CA 1TX4A 3MSXB 5C5SA 1AM4A 3WPQA 3IUGA 2EE4A 2MBGA 3FK2A 5IRCA 5JCPA 1RGPA 3CXLA 3WPSA 5HPYA 1GRNB 3EAPA 5JD0A 3QISA 2XS6A 1PBWA 2NGRB 2QV2A 1XA6A 3KUQA 2EE5A 3BYIA 2OVJA 2OSAA 1OW3A 5C2JA
chains in the Genus database with same CATH superfamily
3W6RA 1F7CA 1TX4A 3MSXB 5C5SA 1AM4A 3WPQA 3IUGA 2EE4A 2MBGA 3FK2A 5IRCA 5JCPA 1RGPA 3CXLA 3WPSA 5HPYA 1GRNB 3EAPA 5JD0A 3QISA 2XS6A 1PBWA 2NGRB 2QV2A 1XA6A 3KUQA 2EE5A 3BYIA 2OVJA 2OSAA 1OW3A 5C2JA
chains in the Genus database with same CATH topology
3W6RA 1F7CA 1TX4A 3MSXB 5C5SA 1AM4A 3WPQA 3IUGA 2EE4A 2MBGA 3FK2A 5IRCA 5JCPA 1RGPA 3CXLA 3WPSA 5HPYA 1GRNB 3EAPA 5JD0A 3QISA 2XS6A 1PBWA 2NGRB 2QV2A 1XA6A 3KUQA 2EE5A 3BYIA 2OVJA 2OSAA 1OW3A 5C2JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W6R A;  1F7C A;  1TX4 A;  3MSX B;  5C5S A;  1AM4 A;  3WPQ A;  3IUG A;  2EE4 A;  2MBG A;  3FK2 A;  5IRC A;  5JCP A;  1RGP A;  3CXL A;  3WPS A;  5HPY A;  1GRN B;  3EAP A;  5JD0 A;  3QIS A;  2XS6 A;  1PBW A;  2NGR B;  2QV2 A;  1XA6 A;  3KUQ A;  2EE5 A;  3BYI A;  2OVJ A;  2OSA A;  1OW3 A;  5C2J A; 
#chains in the Genus database with same CATH topology
 3W6R A;  1F7C A;  1TX4 A;  3MSX B;  5C5S A;  1AM4 A;  3WPQ A;  3IUG A;  2EE4 A;  2MBG A;  3FK2 A;  5IRC A;  5JCP A;  1RGP A;  3CXL A;  3WPS A;  5HPY A;  1GRN B;  3EAP A;  5JD0 A;  3QIS A;  2XS6 A;  1PBW A;  2NGR B;  2QV2 A;  1XA6 A;  3KUQ A;  2EE5 A;  3BYI A;  2OVJ A;  2OSA A;  1OW3 A;  5C2J A; 
#chains in the Genus database with same CATH homology
 3W6R A;  1F7C A;  1TX4 A;  3MSX B;  5C5S A;  1AM4 A;  3WPQ A;  3IUG A;  2EE4 A;  2MBG A;  3FK2 A;  5IRC A;  5JCP A;  1RGP A;  3CXL A;  3WPS A;  5HPY A;  1GRN B;  3EAP A;  5JD0 A;  3QIS A;  2XS6 A;  1PBW A;  2NGR B;  2QV2 A;  1XA6 A;  3KUQ A;  2EE5 A;  3BYI A;  2OVJ A;  2OSA A;  1OW3 A;  5C2J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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