1RGPA

Gtpase-activation domain from rhogap
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
199
structure length
189
Chain Sequence
PRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWINPINTFTKFLLDHQGELF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of the GTPase-activating domain from p50rhoGAP.
pubmed doi rcsb
molecule tags G-protein
source organism Homo sapiens
molecule keywords RHOGAP
total genus 61
structure length 189
sequence length 199
ec nomenclature
pdb deposition date 1996-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1rgpA00
2XS6A 5C2JA 1PBWA 1F7CA 3QISA 1TX4A 5JCPA 1RGPA 5C5SA 2NGRB 3BYIA 3WPQA 5JD0A 5IRCA 3KUQA 3EAPA 2QV2A 2EE5A 1OW3A 5HPYA 1GRNB 3FK2A 3MSXB 3W6RA 3CXLA 1XA6A 3WPSA 2EE4A 2OSAA 2OVJA 3IUGA 2MBGA 1AM4A
chains in the Genus database with same CATH superfamily
2XS6A 5C2JA 1PBWA 1F7CA 3QISA 1TX4A 5JCPA 1RGPA 5C5SA 2NGRB 3BYIA 3WPQA 5JD0A 5IRCA 3KUQA 3EAPA 2QV2A 2EE5A 1OW3A 5HPYA 1GRNB 3FK2A 3MSXB 3W6RA 3CXLA 1XA6A 3WPSA 2EE4A 2OSAA 2OVJA 3IUGA 2MBGA 1AM4A
chains in the Genus database with same CATH topology
2XS6A 5C2JA 1PBWA 1F7CA 3QISA 1TX4A 5JCPA 1RGPA 5C5SA 2NGRB 3BYIA 3WPQA 5JD0A 5IRCA 3KUQA 3EAPA 2QV2A 2EE5A 1OW3A 5HPYA 1GRNB 3FK2A 3MSXB 3W6RA 3CXLA 1XA6A 3WPSA 2EE4A 2OSAA 2OVJA 3IUGA 2MBGA 1AM4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XS6 A;  5C2J A;  1PBW A;  1F7C A;  3QIS A;  1TX4 A;  5JCP A;  1RGP A;  5C5S A;  2NGR B;  3BYI A;  3WPQ A;  5JD0 A;  5IRC A;  3KUQ A;  3EAP A;  2QV2 A;  2EE5 A;  1OW3 A;  5HPY A;  1GRN B;  3FK2 A;  3MSX B;  3W6R A;  3CXL A;  1XA6 A;  3WPS A;  2EE4 A;  2OSA A;  2OVJ A;  3IUG A;  2MBG A;  1AM4 A; 
#chains in the Genus database with same CATH topology
 2XS6 A;  5C2J A;  1PBW A;  1F7C A;  3QIS A;  1TX4 A;  5JCP A;  1RGP A;  5C5S A;  2NGR B;  3BYI A;  3WPQ A;  5JD0 A;  5IRC A;  3KUQ A;  3EAP A;  2QV2 A;  2EE5 A;  1OW3 A;  5HPY A;  1GRN B;  3FK2 A;  3MSX B;  3W6R A;  3CXL A;  1XA6 A;  3WPS A;  2EE4 A;  2OSA A;  2OVJ A;  3IUG A;  2MBG A;  1AM4 A; 
#chains in the Genus database with same CATH homology
 2XS6 A;  5C2J A;  1PBW A;  1F7C A;  3QIS A;  1TX4 A;  5JCP A;  1RGP A;  5C5S A;  2NGR B;  3BYI A;  3WPQ A;  5JD0 A;  5IRC A;  3KUQ A;  3EAP A;  2QV2 A;  2EE5 A;  1OW3 A;  5HPY A;  1GRN B;  3FK2 A;  3MSX B;  3W6R A;  3CXL A;  1XA6 A;  3WPS A;  2EE4 A;  2OSA A;  2OVJ A;  3IUG A;  2MBG A;  1AM4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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