1RGPA

Gtpase-activation domain from rhogap
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
199
structure length
189
Chain Sequence
PRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWINPINTFTKFLLDHQGELF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of the GTPase-activating domain from p50rhoGAP.
pubmed doi rcsb
molecule keywords RHOGAP
molecule tags G-protein
source organism Homo sapiens
total genus 61
structure length 189
sequence length 199
ec nomenclature
pdb deposition date 1996-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1rgpA00
1AM4A 2MBGA 1GRNB 2EE5A 3CXLA 3BYIA 5JD0A 3MSXB 2EE4A 5JCPA 2QV2A 3KUQA 5HPYA 1OW3A 5C2JA 1TX4A 3QISA 3W6RA 1XA6A 2OVJA 2NGRB 1F7CA 5C5SA 1PBWA 3FK2A 2OSAA 3WPQA 3WPSA 3EAPA 5IRCA 2XS6A 1RGPA 3IUGA
chains in the Genus database with same CATH superfamily
1AM4A 2MBGA 1GRNB 2EE5A 3CXLA 3BYIA 5JD0A 3MSXB 2EE4A 5JCPA 2QV2A 3KUQA 5HPYA 1OW3A 5C2JA 1TX4A 3QISA 3W6RA 1XA6A 2OVJA 2NGRB 1F7CA 5C5SA 1PBWA 3FK2A 2OSAA 3WPQA 3WPSA 3EAPA 5IRCA 2XS6A 1RGPA 3IUGA
chains in the Genus database with same CATH topology
1AM4A 2MBGA 1GRNB 2EE5A 3CXLA 3BYIA 5JD0A 3MSXB 2EE4A 5JCPA 2QV2A 3KUQA 5HPYA 1OW3A 5C2JA 1TX4A 3QISA 3W6RA 1XA6A 2OVJA 2NGRB 1F7CA 5C5SA 1PBWA 3FK2A 2OSAA 3WPQA 3WPSA 3EAPA 5IRCA 2XS6A 1RGPA 3IUGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AM4 A;  2MBG A;  1GRN B;  2EE5 A;  3CXL A;  3BYI A;  5JD0 A;  3MSX B;  2EE4 A;  5JCP A;  2QV2 A;  3KUQ A;  5HPY A;  1OW3 A;  5C2J A;  1TX4 A;  3QIS A;  3W6R A;  1XA6 A;  2OVJ A;  2NGR B;  1F7C A;  5C5S A;  1PBW A;  3FK2 A;  2OSA A;  3WPQ A;  3WPS A;  3EAP A;  5IRC A;  2XS6 A;  1RGP A;  3IUG A; 
#chains in the Genus database with same CATH topology
 1AM4 A;  2MBG A;  1GRN B;  2EE5 A;  3CXL A;  3BYI A;  5JD0 A;  3MSX B;  2EE4 A;  5JCP A;  2QV2 A;  3KUQ A;  5HPY A;  1OW3 A;  5C2J A;  1TX4 A;  3QIS A;  3W6R A;  1XA6 A;  2OVJ A;  2NGR B;  1F7C A;  5C5S A;  1PBW A;  3FK2 A;  2OSA A;  3WPQ A;  3WPS A;  3EAP A;  5IRC A;  2XS6 A;  1RGP A;  3IUG A; 
#chains in the Genus database with same CATH homology
 1AM4 A;  2MBG A;  1GRN B;  2EE5 A;  3CXL A;  3BYI A;  5JD0 A;  3MSX B;  2EE4 A;  5JCP A;  2QV2 A;  3KUQ A;  5HPY A;  1OW3 A;  5C2J A;  1TX4 A;  3QIS A;  3W6R A;  1XA6 A;  2OVJ A;  2NGR B;  1F7C A;  5C5S A;  1PBW A;  3FK2 A;  2OSA A;  3WPQ A;  3WPS A;  3EAP A;  5IRC A;  2XS6 A;  1RGP A;  3IUG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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