1RGP | Genus

Total Genus 61

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	61
sequence length	199
structure length	189
Chain Sequence	PRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWINPINTFTKFLLDHQGELF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 189 atoms

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189 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	The structure of the GTPase-activating domain from p50rhoGAP. pubmed doi rcsb
molecule keywords	RHOGAP
molecule tags	G-protein
source organism	Homo sapiens
total genus	61
structure length	189
sequence length	199
ec nomenclature
pdb deposition date	1996-12-05

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00620	RhoGAP	RhoGAP domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.555.10	Mainly Alpha	Orthogonal Bundle	Phosphatidylinositol 3-kinase; Chain A	Rho GTPase activation protein	1rgpA00

3BYIA 5IRCA 1F7CA 3FK2A 1TX4A 3CXLA 3EAPA 2MBGA 5C2JA 1GRNB 1RGPA 2OSAA 3QISA 3MSXB 5JCPA 2OVJA 1XA6A 1PBWA 5JD0A 3WPQA 2EE4A 3KUQA 2QV2A 3IUGA 2XS6A 1AM4A 5C5SA 1OW3A 3WPSA 2NGRB 5HPYA 2EE5A 3W6RA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3BYI A;  5IRC A;  1F7C A;  3FK2 A;  1TX4 A;  3CXL A;  3EAP A;  2MBG A;  5C2J A;  1GRN B;  1RGP A;  2OSA A;  3QIS A;  3MSX B;  5JCP A;  2OVJ A;  1XA6 A;  1PBW A;  5JD0 A;  3WPQ A;  2EE4 A;  3KUQ A;  2QV2 A;  3IUG A;  2XS6 A;  1AM4 A;  5C5S A;  1OW3 A;  3WPS A;  2NGR B;  5HPY A;  2EE5 A;  3W6R A; 
#chains in the Genus database with same CATH topology
 3BYI A;  5IRC A;  1F7C A;  3FK2 A;  1TX4 A;  3CXL A;  3EAP A;  2MBG A;  5C2J A;  1GRN B;  1RGP A;  2OSA A;  3QIS A;  3MSX B;  5JCP A;  2OVJ A;  1XA6 A;  1PBW A;  5JD0 A;  3WPQ A;  2EE4 A;  3KUQ A;  2QV2 A;  3IUG A;  2XS6 A;  1AM4 A;  5C5S A;  1OW3 A;  3WPS A;  2NGR B;  5HPY A;  2EE5 A;  3W6R A; 
#chains in the Genus database with same CATH homology
 3BYI A;  5IRC A;  1F7C A;  3FK2 A;  1TX4 A;  3CXL A;  3EAP A;  2MBG A;  5C2J A;  1GRN B;  1RGP A;  2OSA A;  3QIS A;  3MSX B;  5JCP A;  2OVJ A;  1XA6 A;  1PBW A;  5JD0 A;  3WPQ A;  2EE4 A;  3KUQ A;  2QV2 A;  3IUG A;  2XS6 A;  1AM4 A;  5C5S A;  1OW3 A;  3WPS A;  2NGR B;  5HPY A;  2EE5 A;  3W6R A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1RGPA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations