1RRIA

Dhna complex with 3-(5-amino-7-hydroxy-[1,2,3] triazolo [4,5-d]pyrimidin-2-yl)-benzoic acid
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
121
structure length
121
Chain Sequence
MQDTIFLKGMRFYGYHGALSAENEIGQIFKVDVTLKVDLSEAGRTDNVIDTVHYGEVFEEVKSIMEGKAVNLLEHLAERIANRINSQYNRVMETKVRITKENPPIPGHYDGVGIEIVRENK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
source organism Staphylococcus aureus
publication title Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization.
pubmed doi rcsb
molecule keywords Dihydroneopterin aldolase
total genus 30
structure length 121
sequence length 121
ec nomenclature ec 4.1.2.25: Dihydroneopterin aldolase.
pdb deposition date 2003-12-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02152 FolB Dihydroneopterin aldolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1130.10 Alpha Beta 2-Layer Sandwich GTP Cyclohydrolase I, domain 2 GTP Cyclohydrolase I, domain 2 1rriA00
1N3SA 2O90A 1B9LA 1A8RA 1IS8A 1WM9A 1SQLA 1Z9WA 2DHNA 3UXVA 1WPLA 1RS2A 4IQIA 1NBUC 2NM2A 4FGCA 1WURA 1N3RA 4UQFA 1A9CA 1NBUA 4F8BA 1RSIA 3R2EA 4AEYA 1IS7A 1RRWA 1RRYA 1RSDA 2CG8A 5FARA 3RJ4A 4GHMA 1GTPA 1FB1A 3RZPA 1FBXA 3S19A 1WUQA 1DHNA 1RS4A 3BP1A 1U68A 2NM3A 3V9OA 1RRIA 4DU6A 5F3MA 3O1KA 1N3TA 3UXJA 1NBUB
chains in the Genus database with same CATH superfamily
1N3SA 2O90A 1B9LA 1A8RA 1IS8A 1WM9A 1SQLA 1Z9WA 2DHNA 3UXVA 1WPLA 1RS2A 4IQIA 1NBUC 2NM2A 4FGCA 1WURA 1N3RA 4UQFA 1A9CA 1NBUA 4F8BA 1RSIA 3R2EA 4AEYA 1IS7A 1RRWA 1RRYA 1RSDA 2CG8A 5FARA 3RJ4A 4GHMA 1GTPA 1FB1A 3RZPA 1FBXA 3S19A 1WUQA 1DHNA 1RS4A 3BP1A 1U68A 2NM3A 3V9OA 1RRIA 4DU6A 5F3MA 3O1KA 1N3TA 3UXJA 1NBUB
chains in the Genus database with same CATH topology
1N3SA 2O90A 1B9LA 1A8RA 1IS8A 1WM9A 1SQLA 1Z9WA 2DHNA 3UXVA 1WPLA 1RS2A 4IQIA 1NBUC 2NM2A 4FGCA 1WURA 1N3RA 4UQFA 1A9CA 1NBUA 4F8BA 1RSIA 3R2EA 4AEYA 1IS7A 1RRWA 1RRYA 1RSDA 2CG8A 5FARA 3RJ4A 4GHMA 1GTPA 1FB1A 3RZPA 1FBXA 3S19A 1WUQA 1DHNA 1RS4A 3BP1A 1U68A 2NM3A 3V9OA 1RRIA 4DU6A 5F3MA 3O1KA 1N3TA 3UXJA 1NBUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N3S A;  2O90 A;  1B9L A;  1A8R A;  1IS8 A;  1WM9 A;  1SQL A;  1Z9W A;  2DHN A;  3UXV A;  1WPL A;  1RS2 A;  4IQI A;  1NBU C;  2NM2 A;  4FGC A;  1WUR A;  1N3R A;  4UQF A;  1A9C A;  1NBU A;  4F8B A;  1RSI A;  3R2E A;  4AEY A;  1IS7 A;  1RRW A;  1RRY A;  1RSD A;  2CG8 A;  5FAR A;  3RJ4 A;  4GHM A;  1GTP A;  1FB1 A;  3RZP A;  1FBX A;  3S19 A;  1WUQ A;  1DHN A;  1RS4 A;  3BP1 A;  1U68 A;  2NM3 A;  3V9O A;  1RRI A;  4DU6 A;  5F3M A;  3O1K A;  1N3T A;  3UXJ A;  1NBU B; 
#chains in the Genus database with same CATH topology
 1N3S A;  2O90 A;  1B9L A;  1A8R A;  1IS8 A;  1WM9 A;  1SQL A;  1Z9W A;  2DHN A;  3UXV A;  1WPL A;  1RS2 A;  4IQI A;  1NBU C;  2NM2 A;  4FGC A;  1WUR A;  1N3R A;  4UQF A;  1A9C A;  1NBU A;  4F8B A;  1RSI A;  3R2E A;  4AEY A;  1IS7 A;  1RRW A;  1RRY A;  1RSD A;  2CG8 A;  5FAR A;  3RJ4 A;  4GHM A;  1GTP A;  1FB1 A;  3RZP A;  1FBX A;  3S19 A;  1WUQ A;  1DHN A;  1RS4 A;  3BP1 A;  1U68 A;  2NM3 A;  3V9O A;  1RRI A;  4DU6 A;  5F3M A;  3O1K A;  1N3T A;  3UXJ A;  1NBU B; 
#chains in the Genus database with same CATH homology
 1N3S A;  2O90 A;  1B9L A;  1A8R A;  1IS8 A;  1WM9 A;  1SQL A;  1Z9W A;  2DHN A;  3UXV A;  1WPL A;  1RS2 A;  4IQI A;  1NBU C;  2NM2 A;  4FGC A;  1WUR A;  1N3R A;  4UQF A;  1A9C A;  1NBU A;  4F8B A;  1RSI A;  3R2E A;  4AEY A;  1IS7 A;  1RRW A;  1RRY A;  1RSD A;  2CG8 A;  5FAR A;  3RJ4 A;  4GHM A;  1GTP A;  1FB1 A;  3RZP A;  1FBX A;  3S19 A;  1WUQ A;  1DHN A;  1RS4 A;  3BP1 A;  1U68 A;  2NM3 A;  3V9O A;  1RRI A;  4DU6 A;  5F3M A;  3O1K A;  1N3T A;  3UXJ A;  1NBU B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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