1RRWA

Dhna complexed with 9-methylguanine
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
121
structure length
121
Chain Sequence
MQDTIFLKGMRFYGYHGALSAENEIGQIFKVDVTLKVDLSEAGRTDNVIDTVHYGEVFEEVKSIMEGKAVNLLEHLAERIANRINSQYNRVMETKVRITKENPPIPGHYDGVGIEIVRENK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
source organism Staphylococcus aureus
publication title Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization.
pubmed doi rcsb
molecule keywords Dihydroneopterin aldolase
total genus 31
structure length 121
sequence length 121
ec nomenclature ec 4.1.2.25: Dihydroneopterin aldolase.
pdb deposition date 2003-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02152 FolB Dihydroneopterin aldolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1130.10 Alpha Beta 2-Layer Sandwich GTP Cyclohydrolase I, domain 2 GTP Cyclohydrolase I, domain 2 1rrwA00
1N3RA 1N3TA 1NBUA 4AEYA 5FARA 2DHNA 1IS8A 1A9CA 1GTPA 1SQLA 4DU6A 1RSIA 1B9LA 1Z9WA 1RRWA 1RRYA 1WUQA 4FGCA 4UQFA 1DHNA 3UXJA 1A8RA 4F8BA 1FB1A 3BP1A 2NM2A 4IQIA 1NBUC 4GHMA 2O90A 1WURA 1N3SA 3UXVA 3V9OA 5F3MA 1U68A 1WM9A 2CG8A 1RS2A 1WPLA 2NM3A 3S19A 1RSDA 3RZPA 1RS4A 1IS7A 3R2EA 3RJ4A 1NBUB 3O1KA 1FBXA 1RRIA
chains in the Genus database with same CATH superfamily
1N3RA 1N3TA 1NBUA 4AEYA 5FARA 2DHNA 1IS8A 1A9CA 1GTPA 1SQLA 4DU6A 1RSIA 1B9LA 1Z9WA 1RRWA 1RRYA 1WUQA 4FGCA 4UQFA 1DHNA 3UXJA 1A8RA 4F8BA 1FB1A 3BP1A 2NM2A 4IQIA 1NBUC 4GHMA 2O90A 1WURA 1N3SA 3UXVA 3V9OA 5F3MA 1U68A 1WM9A 2CG8A 1RS2A 1WPLA 2NM3A 3S19A 1RSDA 3RZPA 1RS4A 1IS7A 3R2EA 3RJ4A 1NBUB 3O1KA 1FBXA 1RRIA
chains in the Genus database with same CATH topology
1N3RA 1N3TA 1NBUA 4AEYA 5FARA 2DHNA 1IS8A 1A9CA 1GTPA 1SQLA 4DU6A 1RSIA 1B9LA 1Z9WA 1RRWA 1RRYA 1WUQA 4FGCA 4UQFA 1DHNA 3UXJA 1A8RA 4F8BA 1FB1A 3BP1A 2NM2A 4IQIA 1NBUC 4GHMA 2O90A 1WURA 1N3SA 3UXVA 3V9OA 5F3MA 1U68A 1WM9A 2CG8A 1RS2A 1WPLA 2NM3A 3S19A 1RSDA 3RZPA 1RS4A 1IS7A 3R2EA 3RJ4A 1NBUB 3O1KA 1FBXA 1RRIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N3R A;  1N3T A;  1NBU A;  4AEY A;  5FAR A;  2DHN A;  1IS8 A;  1A9C A;  1GTP A;  1SQL A;  4DU6 A;  1RSI A;  1B9L A;  1Z9W A;  1RRW A;  1RRY A;  1WUQ A;  4FGC A;  4UQF A;  1DHN A;  3UXJ A;  1A8R A;  4F8B A;  1FB1 A;  3BP1 A;  2NM2 A;  4IQI A;  1NBU C;  4GHM A;  2O90 A;  1WUR A;  1N3S A;  3UXV A;  3V9O A;  5F3M A;  1U68 A;  1WM9 A;  2CG8 A;  1RS2 A;  1WPL A;  2NM3 A;  3S19 A;  1RSD A;  3RZP A;  1RS4 A;  1IS7 A;  3R2E A;  3RJ4 A;  1NBU B;  3O1K A;  1FBX A;  1RRI A; 
#chains in the Genus database with same CATH topology
 1N3R A;  1N3T A;  1NBU A;  4AEY A;  5FAR A;  2DHN A;  1IS8 A;  1A9C A;  1GTP A;  1SQL A;  4DU6 A;  1RSI A;  1B9L A;  1Z9W A;  1RRW A;  1RRY A;  1WUQ A;  4FGC A;  4UQF A;  1DHN A;  3UXJ A;  1A8R A;  4F8B A;  1FB1 A;  3BP1 A;  2NM2 A;  4IQI A;  1NBU C;  4GHM A;  2O90 A;  1WUR A;  1N3S A;  3UXV A;  3V9O A;  5F3M A;  1U68 A;  1WM9 A;  2CG8 A;  1RS2 A;  1WPL A;  2NM3 A;  3S19 A;  1RSD A;  3RZP A;  1RS4 A;  1IS7 A;  3R2E A;  3RJ4 A;  1NBU B;  3O1K A;  1FBX A;  1RRI A; 
#chains in the Genus database with same CATH homology
 1N3R A;  1N3T A;  1NBU A;  4AEY A;  5FAR A;  2DHN A;  1IS8 A;  1A9C A;  1GTP A;  1SQL A;  4DU6 A;  1RSI A;  1B9L A;  1Z9W A;  1RRW A;  1RRY A;  1WUQ A;  4FGC A;  4UQF A;  1DHN A;  3UXJ A;  1A8R A;  4F8B A;  1FB1 A;  3BP1 A;  2NM2 A;  4IQI A;  1NBU C;  4GHM A;  2O90 A;  1WUR A;  1N3S A;  3UXV A;  3V9O A;  5F3M A;  1U68 A;  1WM9 A;  2CG8 A;  1RS2 A;  1WPL A;  2NM3 A;  3S19 A;  1RSD A;  3RZP A;  1RS4 A;  1IS7 A;  3R2E A;  3RJ4 A;  1NBU B;  3O1K A;  1FBX A;  1RRI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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